Phase 1 Insulin Resistance Clinical Trials

9 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 19 of 9 trials

Recruiting
Phase 1

Graded Insulin Suppression Test P&F

ObesityInsulin ResistanceHealthy+1 more
Columbia University15 enrolled1 locationNCT06592261
Recruiting
Phase 1

Metabolic Effects of Angiotensin-(1-7)

ObesityInsulin ResistanceHypertension+1 more
Vanderbilt University26 enrolled1 locationNCT02646475
Recruiting
Phase 1

Effect of Insulin Lowering on Lipogenesis

ObesityInsulin ResistanceNon-Alcoholic Fatty Liver Disease+2 more
Columbia University25 enrolled1 locationNCT07403604
Recruiting
Phase 1

Human Models of Selective Insulin Resistance: Alpelisib, Part I

Insulin ResistanceNon-Alcoholic Fatty Liver DiseaseOverweight and Obesity+1 more
Columbia University32 enrolled1 locationNCT06354088
Recruiting
Phase 1

Diazoxide Suppression Test P&F Study

ObesityInsulin ResistanceHyperinsulinemia
Columbia University10 enrolled1 locationNCT06606327
Recruiting
Phase 1

Mitigating the Pro-inflammatory Phenotype of Obesity

ObesityInsulin ResistanceBlood Pressure+3 more
University of Kansas Medical Center60 enrolled1 locationNCT04934228
Recruiting
Phase 1Phase 2

Hyperbaric Oxygen Therapy on Insulin Resistance in Postmenopause

Insulin Resistance Syndrome
Cairo University40 enrolled1 locationNCT06806345
Recruiting
Phase 1

Effect of Fucoidan on glucose control and markers of cardiometabolic health after chronic dosing

Insulin Resistance/sensitivityHypercholesterolaemiaObesity+3 more
University of Tasmania.80 enrolled1 locationACTRN12614000495628
Completed
Phase 1

Fibre, protein and insulin resistance diet study

Insulin resistance in healthy overweight women.Metabolic syndrome in healthy overweight women.Diabetes prevention in healthy overweight women.
Dr Kirsten McAuley72 enrolled1 locationACTRN12607000154404