Phase 1 Kidney Disease Clinical Trials
38 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 38 trials
Recruiting
Phase 1
Adia Med of Winter Park LLC Chronic Kidney Disease Research Study
Kidney Disease, ChronicChronic Kidney DiseaseKidney Disease+2 more
Adia Med of Winter Park LLC100 enrolled1 locationNCT07572890
Recruiting
Phase 1
A Study of ONO-3310 in Healthy Adult Male Subjects and Chronic Kidney Disease Patients With Type 2 Diabetes Mellitus
Chronic Kidney DiseaseType2 Diabetes Mellitus
Ono Pharmaceutical Co., Ltd.120 enrolled1 locationNCT07619157
Recruiting
Phase 1
Phase 1 Study to Evaluate the Safety and Tolerability of Intravenously Administered PYC-003
Autosomal Dominant Polycystic Kidney Disease (ADPKD
PYC Therapeutics166 enrolled10 locationsNCT06714006
Recruiting
Phase 1Phase 2
Immunological Reset to Enable Access to Hla-compatible Kidney Transplantation in Highly Sensitized Patients (RESET)
Kidney TransplantationKidney Failure, ChronicAlloimmunization+3 more
Hospital Universitari Vall d'Hebron Research Institute10 enrolled1 locationNCT07607197
Recruiting
Phase 1
Evaluation of MTX-439 in Healthy Adults and Adults With Diabetic Kidney Disease
healthy adult participantsDiabetic Kidney Disease
Mediar Therapeutics88 enrolled1 locationNCT07473323
Recruiting
Phase 1Phase 2
Breakthrough - T1DM and Chronic Kidney Disease
Chronic Kidney DiseaseDiabete Type 1
University of Chicago10 enrolled1 locationNCT07592000
Recruiting
Phase 1
Sympatholysis in Chronic Kidney Disease
Chronic Kidney Disease
Emory University110 enrolled1 locationNCT02411773
Recruiting
Phase 1Phase 2
A Study to Investigate IGT-303 in Healthy Volunteers and Participants With Chronic Kidney Disease
Healthy VolunteersChronic Kidney Disease
Ingenia Therapeutics INC94 enrolled5 locationsNCT07231679
Recruiting
Phase 1
Safety, Tolerability and Pharmacokinetics of AZD1613 in Adults With Autosomal Dominant Polycystic Kidney Disease
Autosomal Dominant Polycystic Kidney Disease
AstraZeneca40 enrolled15 locationsNCT07228364
Recruiting
Phase 1
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of OJR520 in Healthy Volunteers and Participants With Chronic Kidney Disease
Chronic Kidney Disease
Novartis Pharmaceuticals112 enrolled2 locationsNCT07235059
Not Yet Recruiting
Phase 1
A Phase 1 Randomized, Double-blind, Dose-Escalating Study to Assess the Safety, Tolerability, and Pharmacokinetics of MTX-439 in Healthy Adults and Adults With Diabetic Kidney Disease
Chronic Kidney DiseaseDiabetic Kidney Disease
Mediar Therapeutics88 enrolled1 locationACTRN12626000533392
Recruiting
Phase 1Phase 2
A Study to Learn How Safe and Tolerable Vonsetamig is in Adult Patients With Chronic Kidney Disease (CKD) Who Need Kidney Transplantation and Are Highly Sensitized to Human Leukocyte Antigen (HLA)
Chronic Kidney Disease(CKD)
Regeneron Pharmaceuticals56 enrolled10 locationsNCT05092347
Recruiting
Phase 1
A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4248 in Healthy Participants and Participants With Chronic Kidney Disease and Type 2 Diabetes and to Assess Home Measurements of Creatinine in a Non Interventional Cohort
Chronic Kidney Disease
AstraZeneca124 enrolled5 locationsNCT07024823
Recruiting
Phase 1Phase 2
Effect of Dapagliflozin on Metabolomics and Cardiac Mechanics in Chronic Kidney Disease
Heart FailureChronic Kidney DiseasesKidney Diseases+1 more
Northwestern University60 enrolled1 locationNCT05719714
Recruiting
Phase 1
A Phase I Clinical Trial to Evaluate CMS-D017 Following Single and Multiple Doses in Healthy Participants
Paroxysmal Nocturnal Hemoglobinuria, PNHComplement-mediated Kidney Disease
Shenzhen Kangzhe Biotechnology Co., Ltd.88 enrolled1 locationNCT07462780
Recruiting
Phase 1
Safety and Efficacy of SC101 Via Perirenal Fat Injection for Resistant Hypertension in Patients With Moderate to Severe Chronic Kidney Disease
Resistant Arterial HypertensionChronic Kidney Disease (Stage 3-4)
The First Affiliated Hospital with Nanjing Medical University3 enrolled1 locationNCT07483372
Recruiting
Phase 1Phase 2
A Study to Investigate the Safety, Tolerability, and Preliminary Efficacy With AION-301 Administered by Intravenous Infusion Compared With Placebo Administered by Intravenous Infusion Investigational Intervention in Participants Aged 35 to 75 Years of Age With Chronic Kidney Disease (CKD)
Chronic Kidney Disease Stage 3
AION Healthspan, Inc.36 enrolled2 locationsNCT06721143
Recruiting
Phase 1
A Study of REGEND003 on Patients With Type 2 Diabetes Mellitus (T2DM) and Chronic Kidney Disease (CKD)
Type 2 Diabetes Mellitus (T2DM) and Chronic Kidney Disease (CKD)
Regend Therapeutics15 enrolled1 locationNCT07275788
Recruiting
Phase 1
A Study of Eloralintide (LY3841136) in Participants With Renal Impairment and in Participants With Normal Renal Function
Kidney DiseaseRenal ImpairmentRenal Insufficiency, Chronic+3 more
Eli Lilly and Company28 enrolled2 locationsNCT07426380
Recruiting
Phase 1
Delayed Immunological Tolerance in Patients With Well-functioning Pre-existing HLA-matched Kidney Transplants
Chronic Kidney DiseasesEnd-stage Kidney DiseaseKidney Transplant Failure and Rejection+1 more
University of California, Los Angeles10 enrolled1 locationNCT05525507