Kidney Disease Clinical Trials

28 recruiting

Kidney Disease Trials at a Glance

467 actively recruiting trials for kidney disease are listed on ClinicalTrialsFinder across 6 cities in 78 countries. The largest study group is Not Applicable with 135 trials, with the heaviest enrollment activity in Dallas, Chicago, and Beijing. Lead sponsors running kidney disease studies include AstraZeneca, University of Colorado, Denver, and Brigham and Women's Hospital.

Browse kidney disease trials by phase

Treatments under study

About Kidney Disease Clinical Trials

Looking for clinical trials for Kidney Disease? There are currently 28 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Kidney Disease trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Kidney Disease clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 467 trials

Recruiting
Phase 2

Safety and Tolerability of Difelikefalin in Adolescents on Haemodialysis With Moderate-to-Severe Pruritus

Chronic Kidney DiseasesPruritus
Vifor Fresenius Medical Care Renal Pharma18 enrolled14 locationsNCT06593392
Recruiting
Phase 3

A Study of Mezagitamab in Adults With Primary IgA Nephropathy Kidney Condition

Kidney Disease
Takeda347 enrolled153 locationsNCT06963827
Recruiting
Phase 3

A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure

Chronic Kidney Disease and Hypertension
AstraZeneca5,000 enrolled759 locationsNCT06742723
Recruiting

The German ADPKD Tolvaptan Treatment Registry

ADPKD (Autosomal Dominant Polycystic Kidney Disease)
University of Cologne2,000 enrolled12 locationsNCT02497521
Recruiting
Not Applicable

CommunityRx-Kidney Health

Chronic Kidney Disease (Stages 1-4)
University of North Carolina, Chapel Hill634 enrolled1 locationNCT07237295
Recruiting
Not Applicable

Effects of Replacing High Protein Foods in People With Chronic Kidney Disease

Chronic Kidney Disease Stage 3
Indiana University15 enrolled1 locationNCT07105670
Recruiting
Phase 3

EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)

Kidney Disease, Chronic
Boehringer Ingelheim11,000 enrolled452 locationsNCT06531824
Recruiting

Immune System Related Kidney Disease

Kidney DiseaseNephrotic Syndrome
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)2,000 enrolled1 locationNCT00001979
Recruiting

Mixed Methods Study of Health-Related Social Needs in African American Adults With Chronic Kidney Disease and Type 2 Diabetes Mellitus

Chronic Kidney DiseasesDiabetes Mellitus, Type 2Diabetic Nephropathy Type 2 - Uncontrolled
Medical College of Wisconsin330 enrolled1 locationNCT05692388
Recruiting
Phase 2

PODOMOUNT-Basket, a Study to Test Whether BI 764198 Helps Adults and Adolescents With Different Types of Kidney Disease

Proteinuric Kidney Diseases
Boehringer Ingelheim132 enrolled147 locationsNCT07355296
Recruiting
Phase 2

NAVIGATE Kidney: A Multi-level Intervention to Reduce Kidney Health Disparities

Chronic Kidney DiseasesKidney Diseases
University of Colorado, Denver448 enrolled2 locationsNCT06810622
Recruiting
Phase 2

Study to Assess the Effects of Angiopoietin-like Protein 3 (ANGPTL3) Inhibition in Adult Participants With Diabetic Kidney Disease

Diabetic Kidney Disease (DKD)
Regeneron Pharmaceuticals270 enrolled47 locationsNCT07271186
Recruiting
Phase 3

A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)

Chronic Kidney Disease
Boehringer Ingelheim120 enrolled102 locationsNCT07107945
Recruiting

OPTIMISE-CKD Study_Dapagliflozin Effectiveness in CKD

Chronic Kidney Disease
AstraZeneca14,308 enrolled1 locationNCT07450820
Recruiting
Phase 2

Testosterone Treatment in Men With Chronic Kidney Disease

Hypogonadism, MaleKidney Disease, Chronic
St. Louis University20 enrolled1 locationNCT05249634
Recruiting
Phase 3

Bleeding Reduction in Acute and Chronic Kidney Patients Having Surgery (BRACKETS) Pilot Trial

SurgeryChronic Kidney DiseasesAcute Kidney Injury+1 more
Hamilton Health Sciences Corporation100 enrolled3 locationsNCT06337838
Recruiting
Not Applicable

Effect of Apiban Therapy on AVF Maturation in ESRD Patients

Direct Oral Anticoagulants (DOACs)Arterio-venous Fistula, Maturation, Chronic Kidney DiseaseEndstage Renal Disease
Combined military hospital lahore190 enrolled1 locationNCT07559942
Recruiting
Not Applicable

A Smart Phone Application to Improve Adoption of the 2024 Kidney Disease Improving Global Outcomes (KDIGO) Chronic Kidney Disease (CKD) Guidelines

Chronic Kidney DiseaseProteinuriaBlood Pressure Control+2 more
St. James's Hospital, Ireland80 enrolled2 locationsNCT07561957
Recruiting

Early PKD Observational Cohort Study

Polycystic Kidney Disease
University of Kansas Medical Center250 enrolled3 locationsNCT02936791
Recruiting

Rutgers University Study of the Genetics of Kidney Disease

Kidney Disease, ChronicKidney DiseasesKidney Disease+3 more
Rutgers, The State University of New Jersey50,000 enrolled1 locationNCT07217535