Phase 2 Kidney Disease Clinical Trials
72 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 72 trials
Recruiting
Phase 2
Phase 2 Study of ADX-038 in Complement-Mediated Kidney Disease
IgA Nephropathy (IgAN)IgANC3G+2 more
ADARx Pharmaceuticals, Inc.45 enrolled29 locationsNCT06989359
Recruiting
Phase 2
Phase 2a Study of VX-407 in Participants With ADPKD Who Have a Subset of PKD1 Gene Variants (AGLOW)
Autosomal Dominant Polycystic Kidney Disease (ADPKD
Vertex Pharmaceuticals Incorporated24 enrolled43 locationsNCT07161037
Recruiting
Phase 2
Safety and Tolerability of Difelikefalin in Adolescents on Haemodialysis With Moderate-to-Severe Pruritus
Chronic Kidney DiseasesPruritus
Vifor Fresenius Medical Care Renal Pharma18 enrolled16 locationsNCT06593392
Recruiting
Phase 2
A Study to Evaluate Safety, Tolerability and Efficacy of AP306 at Fixed Doses in Dialysis Participants With Hyperphosphatemia
End Stage Renal Disease on DialysisHyperphosphatemiaChronic Kidney Disease Requiring Chronic Dialysis
R1 Therapeutics168 enrolled26 locationsNCT06712654
Recruiting
Phase 2
PODOMOUNT-Basket, a Study to Test Whether BI 764198 Helps Adults and Adolescents With Different Types of Kidney Disease
Proteinuric Kidney Diseases
Boehringer Ingelheim132 enrolled156 locationsNCT07355296
Recruiting
Phase 2
Safety of RotigotiNe in Patients With Autosomal Dominant Polycystic Kidney Disease
Kidney Diseases
University Hospital, Rouen120 enrolled4 locationsNCT06291116
Recruiting
Phase 1Phase 2
Immunological Reset to Enable Access to Hla-compatible Kidney Transplantation in Highly Sensitized Patients (RESET)
Kidney TransplantationKidney Failure, ChronicAlloimmunization+3 more
Hospital Universitari Vall d'Hebron Research Institute10 enrolled1 locationNCT07607197
Recruiting
Phase 2Phase 3
Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease
Proteinuric Kidney Disease
Vertex Pharmaceuticals Incorporated466 enrolled318 locationsNCT05312879
Recruiting
Phase 2
Equol and Vascular Function in Women With Chronic Kidney Disease
Cerebrovascular functionBlood PressureCognitive Functions+2 more
University of Colorado, Denver74 enrolled1 locationNCT07194590
Recruiting
Phase 2
A Study of the Safety and Activity of Sparsentan for the Treatment of Patients With Immunoglobulin A Nephropathy
Kidney DiseasesImmune System DiseasesAutoimmune Diseases+3 more
University of Leicester24 enrolled6 locationsNCT04663204
Recruiting
Phase 2
Trial of Semaglutide for Diabetic Kidney Disease in Type 1 Diabetes
Type 1 DiabetesDiabetic Kidney Disease
University of Washington60 enrolled4 locationsNCT05822609
Recruiting
Phase 2
ANCHOR Study: A Study to Assess the Safety and Efficacy of ABBV-CLS-628 in Adult Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Autosomal Dominant Polycystic Kidney Disease
Calico Life Sciences LLC240 enrolled75 locationsNCT06902558
Recruiting
Phase 2
Study to Assess the Effects of Angiopoietin-like Protein 3 (ANGPTL3) Inhibition in Adult Participants With Diabetic Kidney Disease
Diabetic Kidney Disease (DKD)
Regeneron Pharmaceuticals270 enrolled51 locationsNCT07271186
Recruiting
Phase 2
A Phase IIb Study to Evaluate the Effect of Dapagliflozin in Combination With Baxdrostat Compared With Baxdrostat on Albuminuria in Participants With Chronic Kidney Disease and High Blood Pressure.
Chronic Kidney Disease and Hypertension
AstraZeneca218 enrolled71 locationsNCT07222917
Recruiting
Phase 1Phase 2
A Study to Investigate IGT-303 in Healthy Volunteers and Participants With Chronic Kidney Disease
Healthy VolunteersChronic Kidney Disease
Ingenia Therapeutics INC94 enrolled5 locationsNCT07231679
Recruiting
Phase 1Phase 2
Breakthrough - T1DM and Chronic Kidney Disease
Chronic Kidney DiseaseDiabete Type 1
University of Chicago10 enrolled1 locationNCT07592000
Recruiting
Phase 2
Sodium Bicarbonate and Mitochondrial Energetics in Persons With CKD
Insulin ResistanceChronic Kidney DiseasesFatigue+4 more
University of California, Davis80 enrolled2 locationsNCT04984226
Recruiting
Phase 2
NAVIGATE Kidney: A Multi-level Intervention to Reduce Kidney Health Disparities
Chronic Kidney DiseasesKidney Diseases
University of Colorado, Denver448 enrolled2 locationsNCT06810622
Recruiting
Phase 2
Testosterone Treatment in Men With Chronic Kidney Disease
Hypogonadism, MaleKidney Disease, Chronic
St. Louis University20 enrolled1 locationNCT05249634
Recruiting
Phase 1Phase 2
A Study to Learn How Safe and Tolerable Vonsetamig is in Adult Patients With Chronic Kidney Disease (CKD) Who Need Kidney Transplantation and Are Highly Sensitized to Human Leukocyte Antigen (HLA)
Chronic Kidney Disease(CKD)
Regeneron Pharmaceuticals56 enrolled10 locationsNCT05092347