Phase 2 Kidney Disease Clinical Trials
63 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 63 trials
Recruiting
Phase 2
Safety and Tolerability of Difelikefalin in Adolescents on Haemodialysis With Moderate-to-Severe Pruritus
Chronic Kidney DiseasesPruritus
Vifor Fresenius Medical Care Renal Pharma18 enrolled14 locationsNCT06593392
Recruiting
Phase 2
PODOMOUNT-Basket, a Study to Test Whether BI 764198 Helps Adults and Adolescents With Different Types of Kidney Disease
Proteinuric Kidney Diseases
Boehringer Ingelheim132 enrolled147 locationsNCT07355296
Recruiting
Phase 2
NAVIGATE Kidney: A Multi-level Intervention to Reduce Kidney Health Disparities
Chronic Kidney DiseasesKidney Diseases
University of Colorado, Denver448 enrolled2 locationsNCT06810622
Recruiting
Phase 2
Study to Assess the Effects of Angiopoietin-like Protein 3 (ANGPTL3) Inhibition in Adult Participants With Diabetic Kidney Disease
Diabetic Kidney Disease (DKD)
Regeneron Pharmaceuticals270 enrolled47 locationsNCT07271186
Recruiting
Phase 2
Testosterone Treatment in Men With Chronic Kidney Disease
Hypogonadism, MaleKidney Disease, Chronic
St. Louis University20 enrolled1 locationNCT05249634
Recruiting
Phase 2
Phase 2 Study of ADX-038 in Complement-Mediated Kidney Disease
IgA Nephropathy (IgAN)IgANC3G+2 more
ADARx Pharmaceuticals, Inc.45 enrolled25 locationsNCT06989359
Recruiting
Phase 2Phase 3
Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease
Proteinuric Kidney Disease
Vertex Pharmaceuticals Incorporated466 enrolled318 locationsNCT05312879
Recruiting
Phase 2
A Phase 2 Study of MZE829 in Adults With APOL1 Kidney Disease
Proteinuric Kidney Disease
Maze Therapeutics56 enrolled81 locationsNCT06830629
Recruiting
Phase 2
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Chronic Kidney Disease
Chronic Kidney Disease
Boehringer Ingelheim416 enrolled156 locationsNCT06926660
Recruiting
Phase 2
A Study to Investigate the Effects of Zibotentan/Dapagliflozin Combination Compared to Dapagliflozin Alone in Adult Participants With Chronic Kidney Disease and High Proteinuria
Chronic Kidney Disease With High Proteinuria
AstraZeneca224 enrolled15 locationsNCT06942910
Recruiting
Phase 2
Ferric Citrate and Chronic Kidney Disease in Children
Chronic Kidney Diseases
University of California, Los Angeles160 enrolled20 locationsNCT04741646
Recruiting
Phase 2
NAD Augmentation in Diabetes Kidney Disease
Type2diabetesDiabetic Kidney Disease
Brigham and Women's Hospital156 enrolled1 locationNCT05759468
Recruiting
Phase 1Phase 2
Effect of Dapagliflozin on Metabolomics and Cardiac Mechanics in Chronic Kidney Disease
Heart FailureChronic Kidney DiseasesKidney Diseases+1 more
Northwestern University60 enrolled1 locationNCT05719714
Recruiting
Phase 2
A Phase IIb Study to Evaluate the Effect of Dapagliflozin in Combination With Baxdrostat Compared With Baxdrostat on Albuminuria in Participants With Chronic Kidney Disease and High Blood Pressure.
Chronic Kidney Disease and Hypertension
AstraZeneca218 enrolled71 locationsNCT07222917
Recruiting
Phase 2
Inaxaplin in Participants With Proteinuric APOL1 Mediated Kidney Disease With or Without Comorbidities
Proteinuric Kidney Disease
Vertex Pharmaceuticals Incorporated45 enrolled35 locationsNCT06794996
Recruiting
Phase 2
The Evaluation of the Drug R3R01 for the Excretion of Protein in the Urine in Patients With Diabetic Kidney Disease.
Diabetic Kidney Disease
River 3 Renal Corp.60 enrolled1 locationNCT06600412
Recruiting
Phase 1Phase 2
A Study to Investigate the Safety, Tolerability, and Preliminary Efficacy With AION-301 Administered by Intravenous Infusion Compared With Placebo Administered by Intravenous Infusion Investigational Intervention in Participants Aged 35 to 75 Years of Age With Chronic Kidney Disease (CKD)
Chronic Kidney Disease Stage 3
AION Healthspan, Inc.36 enrolled2 locationsNCT06721143
Recruiting
Phase 2
Safety and Efficacy of Mesenchymal Stromal Cells (Amimestrocel ) in Diabetic Kidney Disease
Diabetic Kidney Disease (DKD)
Chinese PLA General Hospital120 enrolled6 locationsNCT06969807
Recruiting
Phase 2
Effect of Canagliflozin on Ultrafiltration & Fibrosis in Patients on Peritoneal Dialysis
CKD (Chronic Kidney Disease) Stage 5DESRD
McGill University Health Centre/Research Institute of the McGill University Health Centre30 enrolled1 locationNCT06913647
Recruiting
Phase 2
A Research Study Comparing How Well Different Doses of the Medicine NNC0519-0130 Can Reduce Kidney Damage in People Living With Chronic Kidney Disease
Chronic Kidney Disease
Novo Nordisk A/S465 enrolled147 locationsNCT06717698