Phase 2 Kidney Injury Clinical Trials

30 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 30 trials

Recruiting
Phase 2

LSALT Peptide for Prevention or Attenuation of Acute Kidney Injury (AKI) in Patients Undergoing On-Pump Cardiac Surgery

Acute Kidney InjuryCardiac Surgery
Arch Biopartners Inc.240 enrolled9 locationsNCT05879432
Recruiting
Phase 1Phase 2

Labile Iron Removal by Adding the Iron Chelator MEX-CD1 to Dialysate in Sepsis-Associated Acute Kidney Injury

SepsisAcute Kidney Injury
Centre Hospitalier Universitaire de Nīmes14 enrolled2 locationsNCT07236463
Recruiting
Phase 2

Improving Preterm Kidney Outcomes With Caffeine

Kidney InjuryPre-Term
University of Wisconsin, Madison114 enrolled1 locationNCT07262060
Recruiting
Phase 2

Intravesical Aminophylline for Urgent Ureteral Stenting in Acute Calculous Anuria

Acute Kidney InjuryUreteral CalculiAcute Calculous Anuria+1 more
Beni-Suef University72 enrolled1 locationNCT07617948
Recruiting
Phase 2

Study of the Relaxin Agonist R2R01 in Patients at High Risk for Cardiac Surgery Associated- Acute Kidney Injury

Acute Kidney Injury
River 2 Renal Corp.430 enrolled1 locationNCT07625553
Recruiting
Phase 2

Modified Autologous Leukocyte Cells for the Treatment of Acute Kidney Injury After Cardiac Surgery

Acute Kidney Injury
M2RLAB SL98 enrolled1 locationNCT07052513
Recruiting
Phase 2

Hypertonic Saline Solution to Prevent Acute Kidney Injury After Heart Transplantation

Acute Kidney InjuryHeart Transplantation
Fernando Bacal74 enrolled1 locationNCT05909150
Recruiting
Phase 2

A Study to Investigate the Efficacy, Safety, and Tolerability of AZD4144in Participants With Sepsis-associated Acute Kidney Injury.

SepsisAcute Kidney Injury
AstraZeneca124 enrolled71 locationsNCT07215702
Recruiting
Phase 1Phase 2

Theophylline Prophylaxis During Hypothermia to Limit Neonatal Nephron Damage

Acute Kidney InjuryHIE
Medical College of Wisconsin30 enrolled1 locationNCT05853601
Recruiting
Phase 2

Sodium-Glucose Cotransporter-2 Inhibitor for Patients With Acute Cardiorenal Syndrome

Heart FailureAcute Kidney Injury
Yale University130 enrolled2 locationsNCT07273838
Recruiting
Phase 1Phase 2

Allogeneic HB-adMSCs vs Placebo for the Treatment of Acute Kidney Injury

Acute Kidney Injury
Hope Biosciences LLC70 enrolled3 locationsNCT06654193
Recruiting
Phase 2

Study of APX-115 in Contrast Induced Acute Kidney Injury in Subjects Undergoing PCI

Contrast-Induced Acute Kidney Injury
Aptabio Therapeutics, Inc.280 enrolled14 locationsNCT05758896
Recruiting
Phase 2

Inorganic Nitrate (NaNO3) Prevention of Contrast-Associated Acute Kidney Injury

Kidney Injury, Acute
University of Michigan100 enrolled1 locationNCT07016074
Recruiting
Phase 2Phase 3

Comparison of Early Proton Pump Inhibitor Initiation Versus Usual Care on Acute Kidney Injury in Hemorrhagic Shock Patients

Acute Kidney Injury
The University of Texas Health Science Center, Houston100 enrolled1 locationNCT06531642
Recruiting
Phase 2

The Efficacy and Safety of Sodium-glucose Cotransporter 2 Inhibitors in Patients With Acute Kidney Disease

Acute Kidney Injury
National Taiwan University Hospital264 enrolled1 locationNCT06528405
Recruiting
Phase 2Phase 3

Remote Ischemic Preconditioning for Renal and Cardiac Protection in Congestive Heart Failure (RICH) Trial

Heart FailureAcute Kidney InjuryPercutaneous Coronary Intervention+2 more
VA Office of Research and Development240 enrolled3 locationsNCT04982419
Recruiting
Phase 2

Prevention of Nephrotoxin-Induced Acute Kidney Injury Using Cilastatin

Acute Kidney Injury
Matthew James698 enrolled2 locationsNCT06886464
Recruiting
Phase 2

A Double-blind Non Inferiority Clinical Trial to Compare the Nephroprotection of Cilastatn Versus Thiosulfate in Patients Undergoing Debulking Surgery With Intraoperative Hyperthermic Intraperitoneal Chemotherapy With Cisplatin.

Acute Kidney InjuryDebulking Surgery for Ovarian Cancer
Hospital General Universitario Gregorio Marañon90 enrolled1 locationNCT07229040
Recruiting
Phase 2

Effects of Variation of Sodium Dialysate in ICU

renal replacement therapyAcute Kidney Injury
University Hospital, Montpellier158 enrolled1 locationNCT03329313
Recruiting
Phase 2

A Study to Evaluate the Efficacy and Safety of BX-001N in Preventing Cardiac Surgery-Associated Acute Kidney Injury (CSA-AKI) and Major Adverse Kidney Events (MAKE)

Cardiac Surgery associated Acute kidney injuryIschemia Reperfusion Injury
Bilix Co.,Ltd.40 enrolled5 locationsNCT07164833