Phase 1 Knee Osteoarthritis Clinical Trials

8 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 18 of 8 trials

Recruiting
Phase 1

A Phase Ib Study to Evaluate the Efficacy and Safety of HRS-2129 in Patients With Knee Osteoarthritis

Moderate Pain in Knee OsteoarthritisSevere Pain in Knee Osteoarthritis
Shandong Suncadia Medicine Co., Ltd.200 enrolled1 locationNCT07351968
Recruiting
Phase 1Phase 2

Recombinant Human Growth Hormone (rHGH) for Knee Osteoarthritis (KORR)

Knee Osteoarthritis (Knee OA)
Dr. David Wasserstein34 enrolled1 locationNCT07036003
Recruiting
Phase 1

A Clinical Study to Evaluate the Safety, Tolerability and Efficacy of BBM-A101 in the Treatment of Knee Osteoarthritis.

Knee Osteoarthritis
Belief BioMed (Beijing) Co., Ltd81 enrolled2 locationsNCT07198555
Recruiting
Phase 1

Optimal Anesthetic for Corticosteroid Injections for Knee Osteoarthritis

Knee Osteoarthritis
Foundation for Orthopaedic Research and Education75 enrolled1 locationNCT05906433
Recruiting
Phase 1

Phase I Clinical Trial of UC-MSCs in the Treatment of Knee Osteoarthritis

Knee Osteoarthritis
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology18 enrolled1 locationNCT06463847
Recruiting
Phase 1Phase 2

Allogenic Mesenchymal Stem Cell Intraarticular Injection for Knee Osteoarthritis Therapy

Knee Osteoarthritis
Aarhus University Hospital80 enrolled1 locationNCT05933434
Completed
Phase 1

A Phase 1, Open-label Study to Determine the Safety, Tolerability, and Pharmacokinetics of Multiple Subcutaneous Doses of Pentosan Polysulfate Sodium (PPS) in Healthy Adult Participants

Bone Marrow LesionKnee Osteoarthritis
Paradigm Biopharmaceuticals Pty Ltd24 enrolled1 locationACTRN12620000829910
Active
Phase 1

Effectiveness of Neuromuscle electrical stimulation in rehabilitation of knee osteoarthritis patients

Knee osteoarthritis patients
Aline Mizusaki Imoto123 enrolledACTRN12607000357459