Phase 2 Knee Osteoarthritis Clinical Trials
16 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–16 of 16 trials
Recruiting
Phase 2
Phase II Clinical Trial of UC-MSCs in the Treatment of Knee Osteoarthritis
Knee Osteoarthritis
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology100 enrolled3 locationsNCT07547735
Recruiting
Phase 2
A Trial to Investigate the Safety and Efficacy of Intra-articular 4P004 Injection in Subjects With Knee Synovitis and Osteoarthritis
Knee OsteoarthritisSynovitis of Knee
4Moving Biotech129 enrolled22 locationsNCT07225829
Recruiting
Phase 1Phase 2
Recombinant Human Growth Hormone (rHGH) for Knee Osteoarthritis (KORR)
Knee Osteoarthritis (Knee OA)
Dr. David Wasserstein34 enrolled1 locationNCT07036003
Recruiting
Phase 2
A Study to Assess the Efficacy and Safety of Vutiglabridin in Knee Osteoarthritis Patients
Knee Osteoarthritis (Knee OA)
Glaceum60 enrolled1 locationNCT06845553
Recruiting
Phase 2
Genicular Artery Embolization for Reducing Pain in Medically Refractory Symptomatic Knee Osteoarthritis
Knee OsteoarthritisKnee Osteoarthritis (Knee OA)
University of Chicago50 enrolled1 locationNCT06859164
Recruiting
Phase 2
Initial Pilot Study to Evaluate the Safety and Temporary Symptom Improvement Efficacy of CKD-981
Knee Osteoarthritis
Chong Kun Dang Pharmaceutical100 enrolled1 locationNCT06954766
Recruiting
Phase 2
Enhancing Modulation Effects of Baduanjin Through Neuromodulation for Knee OA
Knee Osteoarthritis
Massachusetts General Hospital140 enrolled1 locationNCT05839535
Recruiting
Phase 1Phase 2
Allogenic Mesenchymal Stem Cell Intraarticular Injection for Knee Osteoarthritis Therapy
Knee Osteoarthritis
Aarhus University Hospital80 enrolled1 locationNCT05933434
Recruiting
Phase 2
Effectiveness of Platelet-rich Plasma Treatment of Knee Osteoarthritis
Knee Osteoarthritis
Universidad Nacional de Entre Rios110 enrolled1 locationNCT05825105
Recruiting
Phase 2
Intra-articular Platelet-Rich Plasma Compared With Viscosupplementation in the Treatment of Knee Osteoarthritis
Knee Osteoarthritis
Endeavor Health100 enrolled1 locationNCT03491761
Recruiting
Phase 2
A Double-Blind, RandoMised, Placebo-Controlled Study to Assess the Efficacy and Safety of oRal deliVery of sodium Pentosan Polysulfate (PPS) compared to placebo in participants with symptomatic kneE osteoarthritis (OA) and dysLipidemia (MaRVeL Study)
Musculoskeletal Knee Osteoarthritis
The University of Sydney92 enrolled1 locationACTRN12621000654853
Recruiting
Phase 2
An Exploratory Phase 2, Randomised, Double-blind, Placebo-controlled Study to Evaluate the Treatment Effect of Pentosan Polysulfate Sodium Compared with Placebo on Synovial Fluid Biomarkers in Participants with Knee Osteoarthritis Pain
Knee Osteoarthritis
Paradigm Biopharmaceuticals Pty Ltd60 enrolled2 locationsACTRN12621000136808
Completed
Phase 2
A phase 2b, randomised double blind placebo controlled multicentre study to evaluate the effects of pentosan polysulfate sodium on treating pain in subjects with osteoarthritis of the knee and subchondral bone marrow lesions
Bone Marrow LesionKnee Osteoarthritis
Paradigm Biopharmaceuticals Pty Ltd126 enrolled6 locationsACTRN12617001311347
Completed
Phase 2
Does amitriptyline reduce pain in knee osteoarthritis?
Painful knee osteoarthritis
Monash University160 enrolled1 locationACTRN12615000301561
Recruiting
Phase 2
A clinical study to assess the efficacy of a green-lipped mussel (GLM) extract in people with knee osteoarthritis.
Knee OsteoarthritisGastrointestinal Symptoms
Aroma New Zealand Limited110 enrolled1 locationACTRN12613000261718
Completed
Phase 2Phase 3
Enhancing the effectiveness of physiotherapy for people with knee osteoarthritis
Knee osteoarthritis
MESH term: Osteoarthritis/Knee
University of Otago75 enrolled1 locationACTRN12612000460808