Phase 2 Lesion Clinical Trials

23 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 23 trials

Recruiting
Phase 2

Phase II Study of Dysplasix™ Intravaginal Suppositories in Patients Patients With High-Risk HPV and Mild Cervical Cytologic Abnormalities

HPV InfectionASC-USUterine Cervical Dysplasia+3 more
Amplexd Therapeutics, Inc.45 enrolled1 locationNCT07572396
Recruiting
Phase 2

A Study to Evaluate the Efficacy and Safety of Frexalimab, Brivekimig, or Rilzabrutinib in Participants Aged 16 to 75 Years With Primary Focal Segmental Glomerulosclerosis or Minimal Change Disease

Focal Segmental GlomerulosclerosisGlomerulonephritis Minimal Lesion
Sanofi84 enrolled69 locationsNCT06500702
Recruiting
Phase 2Phase 3

A Phase 2/3 Study on the Efficacy and Safety of Mangaciclanol for Contrast-Enhanced MRI of CNS or Body in Adult Patients

Known or Highly Suspected Central Nervous System (CNS) LesionKnown or Highly Suspected Body (Excluding CNS) Lesion
GE Healthcare640 enrolled1 locationNCT07472491
Recruiting
Phase 2

Ultra Low Dose Radiation Therapy in Treating Patients With Mycosis Fungoides

Mycosis FungoidesLocalized Skin Lesion
M.D. Anderson Cancer Center50 enrolled1 locationNCT03398161
Recruiting
Phase 2

Photo-Acoustic and Ultrasonographic Mammoscope

Malignant Breast TumoursBenign Breast Lesions
Franciscus Gasthuis & Vlietland (Hospital)180 enrolled1 locationNCT07492589
Recruiting
Phase 2

Clinical Trial Evaluating Secondary HPV Vaccination After Treatment of High-grade Cervical Lesions

Cervical Lesion
Centre Oscar Lambret85 enrolled1 locationNCT06658405
Recruiting
Phase 1Phase 2

Assessing Changes in Multi-parametric MRI in MS Patients Taking Clemastine Fumarate as a Myelin Repair Therapy

Multiple Sclerosis (MS)Multiple Sclerosis, Relapsing-RemittingMultiple Sclerosis, Primary Progressive+4 more
University of California, San Francisco74 enrolled1 locationNCT05359653
Recruiting
Phase 2

Phase II Randomized, Placebo- Controlled Study of Intralesional Nivolumab for High-risk Oral Premalignant Lesions

Premalignant Lesion
M.D. Anderson Cancer Center45 enrolled1 locationNCT06561087
Recruiting
Phase 2

Evaluation of NWRD08 for HPV-16 and/or HPV-18 Related Cervical HSIL

High-grade Squamous Intraepithelial Lesion (HSIL)
Newish Biotech (Wuxi) Co., Ltd.150 enrolled5 locationsNCT07175662
Recruiting
Phase 2

Premedication With N-acetylcysteine and Simethicone to Improve Mucosal Visualization in Elective Upper Endoscopy

EsophagogastroduodenoscopySimethiconeN-Acetylcysteine+7 more
Hospital General de Mexicali132 enrolled2 locationsNCT07245095
Recruiting
Phase 2

Efficacy of Carminal in Helicobacter Pylori Gastritis

H.Pylori InfectionGastritis Associated With Helicobacter PyloriH Pylori Gastritis+2 more
Catalysis SL80 enrolled2 locationsNCT07179237
Recruiting
Phase 2

Neoadjuvant Chemotherapy Plus Cadonilimab for Locally Advanced Cervical Cancer

Locally Advanced Cervical CancerFemale, Age ≥ 18 Years OldNo Previous Systemic Treatment for the Current Disease, Including Surgery, Antitumor Radiochemotherapy/Immunotherapy+6 more
The First Affiliated Hospital of Zhengzhou University29 enrolled1 locationNCT07104149
Recruiting
Phase 2

Artesunate Ointment for the Treatment of Anal HSIL in HIV-negative Participants

Anal High Grade Squamous Intraepithelial LesionAnal HSILAnal HPV Infection+1 more
Frantz Viral Therapeutics, LLC48 enrolled2 locationsNCT06206564
Recruiting
Phase 1Phase 2

Safety and Exploratory Efficacy of Transplantation Therapy Using PSA-NCAM(+) NPC in AIS-A Level of Sub-acute SCI

Spinal Cord Injury, AcuteSpinal Cord Injury at C4 Level With Complete LesionSpinal Cord Injury at C5-C7 Level With Complete Lesion
S.Biomedics Co., Ltd.5 enrolled2 locationsNCT04812431
Recruiting
Phase 2

'SOURCE - LUNG' Stereotactic Ablative Radiation Therapy Of UltRaCEntral LUNG Tumours (SOURCE Lung)

NSCLC/Oligometastatic Cancer (Single Lung Lesion)
Cancer Trials Ireland68 enrolled2 locationsNCT04375904
Recruiting
Phase 2

Topical 10% Povidone-Iodine in Preventing White Spots

White spot lesionsGingival Inflammation and Bleeding
University of Washington80 enrolled1 locationNCT06616207
Not Yet Recruiting
Phase 2

Part A: A Study of ABI-2280 Vaginal Tablet in Participants with Cervical Intraepithelial neoplasia

Cervical Squamous Intraepithelial Lesions
Antiva Bioscience, Inc.9 enrolled2 locationsACTRN12622001065785
Recruiting
Phase 2

Effect of enoxaparin (a low molecular weight heparin) given in a single or split dose, on stroke occurrence after unruptured brain aneurysm treatment utilising coils or stents

Intracranial LesionsIntracranial Aneurysm
Professor Alan Coulthard124 enrolled1 locationACTRN12620001128987
Completed
Phase 2

A phase 2b, randomised double blind placebo controlled multicentre study to evaluate the effects of pentosan polysulfate sodium on treating pain in subjects with osteoarthritis of the knee and subchondral bone marrow lesions

Bone Marrow LesionKnee Osteoarthritis
Paradigm Biopharmaceuticals Pty Ltd126 enrolled6 locationsACTRN12617001311347
Not Yet Recruiting
Phase 2

A study using non-expanded stem cells for the treatment of early osteoarthritis of the knee (focal chondral defects) in comparison to standard conservative management.

Focal chondral lesions of the knee
Cell-Innovations Pty Ltd32 enrolled1 locationACTRN12616001259437