Phase 3 Liver Metastases Clinical Trials
16 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–16 of 16 trials
Recruiting
Phase 2Phase 3
Neoadjuvant Serplulimab & Bevacizumab With FOLFOX vs. FOLFOX Alone in RAS/BRAF WT, pMMR/MSS CRC Patients
Colorectal, CancerLiver Metastases
Sun Yat-sen University156 enrolled1 locationNCT06280495
Recruiting
Phase 2Phase 3
Tissue Analysis After Tumor Ablation for Liver Metastases Leading to Immediate Retreatment
Liver Metastases
Memorial Sloan Kettering Cancer Center200 enrolled1 locationNCT04143516
Recruiting
Phase 3
Ultra-high Dose Radiation for Liver Metastasis Using MR-guided TReatment With Stereotactic Ablative Single-fraction
Liver Metastases
University Health Network, Toronto114 enrolled1 locationNCT06362395
Recruiting
Phase 3
Adjuvant FOLFIRI Based-chemotherapy After Resection of CLM Responding to Preoperative FOLFIRI
Colorectal, CancerColorectal Liver Metastases
Assistance Publique - Hôpitaux de Paris254 enrolled1 locationNCT06501482
Recruiting
Phase 3
SBRT + PD-1 Monoclonal Antibody in Unresectable Colorectal Liver Metastases
Colorectal, CancerLiver Metastases
Jun Huang24 enrolled1 locationNCT06794086
Recruiting
Phase 3
Induction Treatment for Initially Unresectable Colorectal Liver Metastases: Combined Hepatic Arterial Infusion Pump Therapy With Systemic Therapy
Liver MetastasesColorectal NeoplasmsFloxuridine+1 more
The Netherlands Cancer Institute306 enrolled1 locationNCT06857773
Recruiting
Phase 3
Conversion Therapy of RAS/BRAF Wild-Type Colorectal Cancer Patients With Initially Unresectable Liver Metastases
Colorectal, CancerLiver Metastases
Fudan University508 enrolled1 locationNCT04687631
Recruiting
Phase 3
PHP in Combination With IPI1/NIVO3 Compared to IPI3/NIVO1 Only in Patients With Uveal Melanoma Liver Metastases
Liver MetastasesUveal Melanoma
Vastra Gotaland Region40 enrolled6 locationsNCT06519266
Recruiting
Phase 3
Improved Recovery by Iron Following Surgery With Blood Loss, the IRIS-trial
Liver CancerSurgeryLiver Metastases+2 more
Jon Unosson338 enrolled1 locationNCT05744219
Recruiting
Phase 2Phase 3
COLDFIRE-III Trial: Efficacy of Irreversible Electroporation and Stereotactic Body Radiotherapy for Perivascular and Peribiliary Colorectal Liver Metastases
Colorectal, CancerLiver MetastasesUnresectable Solid Tumor+1 more
Amsterdam UMC, location VUmc78 enrolled1 locationNCT06185556
Recruiting
Phase 3
Regorafenib Combined With Irinotecan Drug-Eluting Beads for Colorectal Cancer Liver Metastases
RegorafenibColorectal Cancer Liver Metastases
Sun Yat-sen University126 enrolled1 locationNCT05794971
Recruiting
Phase 3
COLLISION RELAPSE Trial
Colorectal, CancerSurgeryLiver Metastases+3 more
Amsterdam UMC, location VUmc360 enrolled1 locationNCT05861505
Recruiting
Phase 3
ctDNA-guided Adjuvant Chemotherapy in Liver Metastasis of Colorectal Cancer
Colorectal, CancerLiver MetastasesCirculating Tumor Cell+1 more
Sixth Affiliated Hospital, Sun Yat-sen University490 enrolled1 locationNCT05815082
Recruiting
Phase 3
Postoperation Maintenance Therapy for Resectable Liver Metastases of Colorectal Cancer Guided by ctDNA
Colorectal, CancerLiver MetastasesCirculating Tumor Cell+1 more
Sixth Affiliated Hospital, Sun Yat-sen University346 enrolled1 locationNCT05797077
Recruiting
Phase 3
BreCLIM-2 - A RCT Investigating Local Treatment for Breast Cancer Liver Metastases
Breast CancerLiver Metastases
Umeå University200 enrolled1 locationNCT04079049
Recruiting
Phase 3
mFOLFOXIRI+Bev vs. mFOLFOX6+Bev for RAS Mutant Unresectable Colorectal Liver-limited Metastases
Colorectal CarcinomaLiver Metastases
Fudan University308 enrolled1 locationNCT04781270