Phase 2 Liver Clinical Trials
151 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 151 trials
Recruiting
Phase 1Phase 2
Safety of HRX215 in Patients After Minor and Major Liver Resection
Liver ResectionColorectal Carcinoma Liver Metastases
HepaRegeniX GmbH80 enrolled6 locationsNCT06638502
Recruiting
Phase 2
Tirzepatide in MetALD
Alcohol Use DisorderMetabolic Alcohol-associated Liver Disease
National Institute on Alcohol Abuse and Alcoholism (NIAAA)120 enrolled1 locationNCT07046819
Recruiting
Phase 2
A Study to Test Whether BI 3802876 is Tolerated in People With Compensated Liver Cirrhosis Due to Metabolic Dysfunction- Associated Steatohepatitis (MASH)
Liver Cirrhosis
Boehringer Ingelheim29 enrolled27 locationsNCT07325526
Recruiting
Phase 2
Y-90 Treatment Response Using Transarterial Radioembolization
Liver CancerHepatocellular CarcinomaPrimary Liver Cancer+3 more
Thomas Jefferson University30 enrolled1 locationNCT07145801
Recruiting
Phase 2
Early Signals of the Transition From Immune Quiescence to Activation in the Liver Allograft Microenvironment and in the Circulation
Liver Transplant
National Institute of Allergy and Infectious Diseases (NIAID)100 enrolled10 locationsNCT07549503
Recruiting
Phase 1Phase 2
GPC3-Targeted T-Cell Therapy (ECT204) in Adults With Advanced HCC
Hepatocellular CarcinomaMetastatic Liver CancerLiver Cancer, Adult+1 more
Eureka Therapeutics Inc.60 enrolled8 locationsNCT04864054
Recruiting
Phase 2
Translation of Acoustic Angiography: Contrast Enhanced Super Resolution (CESR) Imaging
Breast CancerKidney NeoplasmsLiver Neoplasms
UNC Lineberger Comprehensive Cancer Center40 enrolled1 locationNCT07225114
Recruiting
Phase 2
A Trial to Evaluate Efficacy and Safety of Maridebart Cafraglutide in Adults Living With Elevated Liver Fat and Obesity or Overweight
Overweight or Obesity and Elevated Liver Fat
Amgen180 enrolled22 locationsNCT07441252
Recruiting
Phase 1Phase 2
Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.
Hepatocellular CarcinomaMetastatic Hepatocellular CarcinomaUnresectable Hepatocellular Carcinoma+4 more
Pfizer138 enrolled35 locationsNCT07227012
Recruiting
Phase 2
Liver Cirrhosis Network Rosuvastatin Efficacy and Safety for Cirrhosis in the United States
CirrhosisCirrhosis, LiverCirrhosis Due to Hepatitis B+5 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)256 enrolled13 locationsNCT05832229
Recruiting
Phase 1Phase 2
Hepzato Kit and Opdualag for Metastatic Melanoma and Liver Metastasis
Metastatic MelanomaLiver Metastases
University of Wisconsin, Madison15 enrolled1 locationNCT07281924
Recruiting
Phase 2
Evaluation of the Safety and Efficacy of Treatment w/High Dose Melphalan Given Directly Into the Liver Followed by Treatment w/Approved Cancer Treatment or Approved Cancer Treatment Alone in Patients w/ Metastatic Breast Cancer w/Liver Dominant Disease
Metastatic Breast Cancer in the Liver
Delcath Systems Inc.90 enrolled5 locationsNCT06875128
Recruiting
Phase 2
SMART Diets for MASLD
Metabolic Dysfunction-Associated Steatotic Liver Disease
Michigan State University102 enrolled1 locationNCT07459504
Recruiting
Phase 2Phase 3
Trop2-targeted immunoPET Imaging of Solid Tumors
Liver CancerOvarian CancerCervical Cancer+11 more
RenJi Hospital400 enrolled1 locationNCT06851663
Recruiting
Phase 2
Digoxin In NASH (CODIN)
MASLDMASH - Metabolic Dysfunction-Associated SteatohepatitisFatty Liver Disease+5 more
Yale University144 enrolled2 locationsNCT06588699
Recruiting
Phase 2
Short Stitch Versus Traditional Suture for the Prevention of Incisional Hernia After Open Hepatectomy
Metastatic Malignant Neoplasm in the LiverLiver and Intrahepatic Bile Duct NeoplasmPrimary Malignant Liver Neoplasm
M.D. Anderson Cancer Center140 enrolled1 locationNCT04982653
Recruiting
Phase 2
Expanding Liver Transplant Immunosuppression Minimization Via Everolimus
Liver Transplant
National Institute of Allergy and Infectious Diseases (NIAID)340 enrolled8 locationsNCT06280950
Recruiting
Phase 2
Study of AZD2389 Safety, Tolerability, and Pharmacodynamics in Adults With Steatotic Liver Disease and Advanced Fibrosis
Hepatic CirrhosisLiver Fibrosis
AstraZeneca104 enrolled19 locationsNCT07610837
Recruiting
Phase 1Phase 2
A Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatment Combinations in Patients With Advanced Liver Cancers (Morpheus-Liver)
Advanced Liver Cancers
Hoffmann-La Roche518 enrolled33 locationsNCT04524871
Recruiting
Phase 2
Cemiplimab and Transarterial Radioembolization With Y-90 SIR-S Spheres for the Treatment of Liver Directed Metastatic Breast Cancer
Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast CarcinomaMetastatic Carcinoma in the Liver
City of Hope Medical Center11 enrolled1 locationNCT06860815