Lung Cancer Clinical Trials in Toronto, Ontario

39 recruitingToronto, Ontario, Canada

Showing 120 of 39 trials

Recruiting
Phase 3

A Study of Calderasib (MK-1084) Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004/KANDLELIT-004)

Non-small Cell Lung Cancer
Merck Sharp & Dohme LLC600 enrolled215 locationsNCT06345729
Recruiting
Phase 1

Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers

Non-small Cell Lung CancerPancreatic Ductal AdenocarcinomaHR+/HER2- Ductal and Lobular Breast Cancer
Novartis Pharmaceuticals162 enrolled31 locationsNCT06562192
Recruiting
Phase 1

A Study to Evaluate the Safety, Tolerability, and Efficacy of Escalating Doses of BMS-986463 in Participants With Select Advanced Malignant Tumors.

Non-small Cell Lung Cancer (NSCLC)High-grade Serous Ovarian Carcinoma (HGSOC)Uterine Serous Carcinoma (USC)
Bristol-Myers Squibb240 enrolled17 locationsNCT06476808
Recruiting
Phase 3

Radiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung Cancer

Non-small Cell Lung Cancer
Canadian Cancer Trials Group320 enrolled57 locationsNCT06686771
Recruiting
Phase 1Phase 2

A Study to Evaluate the Safety, Tolerability, and Efficacy of BMS-986523 Alone and in Combination With Anti-Cancer Agents in Participants With Advanced Solid Malignancies

Non-small Cell Lung Cancer (NSCLC)Pancreatic Ductal Adenocarcinoma (PDAC)Advanced Solid Malignancies+1 more
Bristol-Myers Squibb252 enrolled8 locationsNCT07223047
Recruiting
Phase 3

A Study to Assess the Efficacy and Safety of Zipalertinib Versus Placebo for Adjuvant Treatment in Participants With Stage IB-IIIA NSCLC With Uncommon EGFR Mutations, Following Complete Tumor Resection

Lung CancerEGFRNSCLC, Stage IB-IIIA+5 more
Taiho Oncology, Inc.360 enrolled253 locationsNCT07128199
Recruiting
Phase 1

A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors

Urothelial CarcinomaBladder CancerAdvanced/Metastatic Solid Tumors+1 more
Pfizer310 enrolled28 locationsNCT07090499
Recruiting
Phase 2Phase 3

Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7

Advanced Non-Small Cell Lung Cancer
Mirati Therapeutics Inc.806 enrolled764 locationsNCT04613596
Recruiting

The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study

Breast CancerLiver CancerEsophageal Cancer+35 more
UMC Utrecht8,000 enrolled18 locationsNCT04075305
Recruiting
Phase 1

Talazoparib and Thoracic RT for ES-SCLC

Lung Cancer
University Health Network, Toronto24 enrolled1 locationNCT04170946
Recruiting
Phase 3

The Thoracic Peri-Operative Integrative Surgical Care Evaluation Trial - Stage III

Esophageal CancerGastric CancerLung Cancer
Ottawa Hospital Research Institute20 enrolled2 locationsNCT04871412
Recruiting
Phase 1Phase 2

Phase 1/2a Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of WEF-001 as Monotherapy in Advanced KRAS-Mutant Solid Tumours.

Advanced Solid TumorsAdvanced or Metastatic KRAS-mutant Tumor in Pancreatic AdenocarcinomaAdvanced or Metastatic KRAS-mutant Tumor in Colorectal Cancer+2 more
Auricula Biosciences Inc.110 enrolled4 locationsNCT07148128
Recruiting

Liquid Biopsy Evaluation and Repository Development at Princess Margaret

Breast CancerOvarian CancerLung Cancer+15 more
University Health Network, Toronto2,500 enrolled1 locationNCT03702309
Recruiting
Not Applicable

Sustainable Implementation of the EXCEL Exercise Oncology Program Across Canada

Lung CancersCancerColon Cancer+2 more
University of Calgary740 enrolled5 locationsNCT06960291
Recruiting
Phase 2

Investigating the Effects of Atezolizumab in People Whose Tumour DNA or RNA Indicates Possible Sensitivity

Breast CancerSarcomaLung Cancer+6 more
British Columbia Cancer Agency200 enrolled2 locationsNCT04273061
Recruiting
Phase 2

Study of Autologous Tumor Infiltrating Lymphocytes in Patients With Solid Tumors

Non-small Cell Lung CancerMetastatic MelanomaSquamous Cell Carcinoma of the Head and Neck
Iovance Biotherapeutics, Inc.245 enrolled45 locationsNCT03645928
Recruiting
Not Applicable

Non-ablative Oligofractionated Radiation Therapy Before Surgical Transplantation As Radiovaccination

Transplant-Related Lung Cancer
Marc de Perrot30 enrolled1 locationNCT04782752
Recruiting

Genomic Investigation of Unusual Responders

Breast CancerCancerNon-small Cell Lung Cancer
University Health Network, Toronto100 enrolled1 locationNCT03740503
Recruiting

Ontario-wide Cancer TArgeted Nucleic Acid Evaluation

Breast CancerLung Cancer
University Health Network, Toronto10,000 enrolled7 locationsNCT02906943
Recruiting
Not Applicable

The SOAR Study: a Study of Geriatric Assessment and Exercise for Older Adults and Their Support Person

Lung Cancer
Martine Puts60 enrolled2 locationsNCT05509751