Phase 1 Malignant Tumors Clinical Trials
21 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 21 trials
Recruiting
Phase 1
A Clinical Trial to Assess COM503 in Participants With Advanced Solid Malignancies
NeoplasmCancer, Malignant Tumors
Compugen Ltd200 enrolled11 locationsNCT06759649
Recruiting
Phase 1
A Phase I Study of SPGL008 in Subjects With Advanced Malignant Tumors
Advanced Malignant Tumors
Shenyang Sunshine Pharmaceutical Co., LTD.96 enrolled1 locationNCT07038005
Recruiting
Phase 1Phase 2
Efficacy and Safety of MSLN CAR-T in Advanced Malignant Tumors
Advanced Solid Malignant Tumors (With Positive Expression of MSLN in Tumor Tissue)
Shenzhen University General Hospital20 enrolled1 locationNCT07399769
Recruiting
Phase 1Phase 2
Evaluation of the Safety, Tolerability and Efficacy of iNeo-Vac-R01, an Individualized mRNA Therapeutic Technology Based on Tumor Neoantigens, for Adjuvant Treatment in Patients With Biliary Malignant Tumors After Radical Resection
Biliary Malignant Tumors
Yifan Wang20 enrolled1 locationNCT07368803
Recruiting
Phase 1Phase 2
First-in-Human Investigation of JMT108 Injection in Participants With Advanced Malignant Tumors
Advanced Malignant Tumors
Shanghai JMT-Bio Inc.436 enrolled1 locationNCT06877650
Recruiting
Phase 1
A Phase 1 Study of SSGJ-709 in Patients With Advanced Malignant Tumors
Advanced Malignant Tumors
Shenyang Sunshine Pharmaceutical Co., LTD.15 enrolled1 locationNCT07016490
Recruiting
Phase 1Phase 2
A Study of LM-350 in Subjects With Advanced Solid Tumours
Malignant Tumors
LaNova Medicines Limited80 enrolled4 locationsNCT07112222
Recruiting
Phase 1Phase 2
Phase I/II Clinical Study of SHR-1501 Combined With Adbelizumab in Patients With Malignant Tumors
Patients With Advanced or Metastatic Malignant Tumors
Shanghai Hengrui Pharmaceutical Co., Ltd.203 enrolled1 locationNCT07073534
Recruiting
Phase 1
A Clinical Trial Evaluating Injection of TQB6411 in Subjects With Advanced Malignant Tumors
Advanced Malignant Tumors
Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.216 enrolled19 locationsNCT07043751
Recruiting
Phase 1
A Clinical Study of SHR-4506 Injection in Patients With Malignant Tumors
Malignant Tumors of Adults
Suzhou Suncadia Biopharmaceuticals Co., Ltd.102 enrolled2 locationsNCT07068932
Recruiting
Phase 1
A Phase I Study of SSGJ-612 in Patients With Advanced Solid Tumors
Advanced Malignant Tumors
Shenyang Sunshine Pharmaceutical Co., LTD.30 enrolled1 locationNCT07032298
Recruiting
Phase 1
Application of KRAS Vaccine in the Treatment of KRAS-mutated Malignancies
Malignant Tumors
Sichuan University20 enrolled1 locationNCT07004244
Recruiting
Phase 1Phase 2
A Phase I/II Clinical Trial of LBL-033 in the Treatment of Advanced Malignant Tumors
Advanced Malignant Tumors
Nanjing Leads Biolabs Co.,Ltd468 enrolled6 locationsNCT05779163
Recruiting
Phase 1Phase 2
Study of LM-299 in Subjects Advanced Malignant Tumors
Malignant Tumors
LaNova Medicines Limited108 enrolled6 locationsNCT06650566
Recruiting
Phase 1
A Phase I Clinical Study of SSS59 Monotherapy in Patients With Advanced Malignant Tumors
Malignant Tumors
Shenyang Sunshine Pharmaceutical Co., LTD.154 enrolled1 locationNCT06944444
Recruiting
Phase 1
A Phase Ia/Ib Open Label，Clinical Study Evaluating the Safety, Tolerability and Preliminary Efficacy of AK127 in Combination With AK104 in Patients With Advanced Malignant Tumors
Advanced Malignant Tumors
Akeso205 enrolled1 locationNCT05868876
Recruiting
Phase 1
A Study of AK129 in Patients With Advanced Malignant Tumors
Advanced Malignant Tumors(Stage IA-IB)
Akeso182 enrolled1 locationNCT05645276
Recruiting
Phase 1Phase 2
A Clinical Trial to Evaluate Effect of IBB0979 in Patients With Advanced Malignant Tumors
Advanced Malignant Tumors
SUNHO（China）BioPharmaceutical CO., Ltd.25 enrolled1 locationNCT05991583
Recruiting
Phase 1Phase 2
A Phase I/II Study of LM-101 Injection in Patients With Advanced Malignant Tumors
Malignant Tumors
LaNova Medicines Limited139 enrolled5 locationsNCT05615974
Recruiting
Phase 1
A Study of NBL-020 Injection in Subjects With Advanced Malignant Tumors.
Advanced Malignant Tumors
NovaRock Biotherapeutics, Ltd200 enrolled1 locationNCT05877924