Phase 1 Malignant Tumors Clinical Trials
22 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 22 trials
Recruiting
Phase 1
A Study of BMS-986488 as Monotherapy and Combination Therapy in Participants With Advanced Malignant Tumors
Advanced Malignant Tumors
Bristol-Myers Squibb437 enrolled8 locationsNCT06764771
Recruiting
Phase 1
A Clinical Study of SHR-4506 Injection in Patients With Malignant Tumors
Malignant Tumors of Adults
Suzhou Suncadia Biopharmaceuticals Co., Ltd.102 enrolled2 locationsNCT07068932
Recruiting
Phase 1
A Clinical Trial to Assess COM503 in Participants With Advanced Solid Malignancies
NeoplasmCancer, Malignant Tumors
Compugen Ltd200 enrolled11 locationsNCT06759649
Recruiting
Phase 1
A Phase I Study of SPGL008 in Subjects With Advanced Malignant Tumors
Advanced Malignant Tumors
Shenyang Sunshine Pharmaceutical Co., LTD.96 enrolled1 locationNCT07038005
Recruiting
Phase 1Phase 2
Efficacy and Safety of MSLN CAR-T in Advanced Malignant Tumors
Advanced Solid Malignant Tumors (With Positive Expression of MSLN in Tumor Tissue)
Shenzhen University General Hospital20 enrolled1 locationNCT07399769
Recruiting
Phase 1Phase 2
Evaluation of the Safety, Tolerability and Efficacy of iNeo-Vac-R01, an Individualized mRNA Therapeutic Technology Based on Tumor Neoantigens, for Adjuvant Treatment in Patients With Biliary Malignant Tumors After Radical Resection
Biliary Malignant Tumors
Yifan Wang20 enrolled1 locationNCT07368803
Recruiting
Phase 1Phase 2
First-in-Human Investigation of JMT108 Injection in Participants With Advanced Malignant Tumors
Advanced Malignant Tumors
Shanghai JMT-Bio Inc.436 enrolled1 locationNCT06877650
Recruiting
Phase 1
A Phase 1 Study of SSGJ-709 in Patients With Advanced Malignant Tumors
Advanced Malignant Tumors
Shenyang Sunshine Pharmaceutical Co., LTD.15 enrolled1 locationNCT07016490
Recruiting
Phase 1Phase 2
A Study of LM-350 in Subjects With Advanced Solid Tumours
Malignant Tumors
LaNova Medicines Limited80 enrolled4 locationsNCT07112222
Recruiting
Phase 1Phase 2
Phase I/II Clinical Study of SHR-1501 Combined With Adbelizumab in Patients With Malignant Tumors
Patients With Advanced or Metastatic Malignant Tumors
Shanghai Hengrui Pharmaceutical Co., Ltd.203 enrolled1 locationNCT07073534
Recruiting
Phase 1
A Clinical Trial Evaluating Injection of TQB6411 in Subjects With Advanced Malignant Tumors
Advanced Malignant Tumors
Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.216 enrolled19 locationsNCT07043751
Recruiting
Phase 1
A Phase I Study of SSGJ-612 in Patients With Advanced Solid Tumors
Advanced Malignant Tumors
Shenyang Sunshine Pharmaceutical Co., LTD.30 enrolled1 locationNCT07032298
Recruiting
Phase 1
Application of KRAS Vaccine in the Treatment of KRAS-mutated Malignancies
Malignant Tumors
Sichuan University20 enrolled1 locationNCT07004244
Recruiting
Phase 1Phase 2
A Phase I/II Clinical Trial of LBL-033 in the Treatment of Advanced Malignant Tumors
Advanced Malignant Tumors
Nanjing Leads Biolabs Co.,Ltd468 enrolled6 locationsNCT05779163
Recruiting
Phase 1Phase 2
Study of LM-299 in Subjects Advanced Malignant Tumors
Malignant Tumors
LaNova Medicines Limited108 enrolled6 locationsNCT06650566
Recruiting
Phase 1
A Phase I Clinical Study of SSS59 Monotherapy in Patients With Advanced Malignant Tumors
Malignant Tumors
Shenyang Sunshine Pharmaceutical Co., LTD.154 enrolled1 locationNCT06944444
Recruiting
Phase 1
A Study of AK129 in Patients With Advanced Malignant Tumors
Advanced Malignant Tumors(Stage IA-IB)
Akeso182 enrolled1 locationNCT05645276
Recruiting
Phase 1
A Phase Ia/Ib Open Label，Clinical Study Evaluating the Safety, Tolerability and Preliminary Efficacy of AK127 in Combination With AK104 in Patients With Advanced Malignant Tumors
Advanced Malignant Tumors
Akeso205 enrolled1 locationNCT05868876
Recruiting
Phase 1Phase 2
A Clinical Trial to Evaluate Effect of IBB0979 in Patients With Advanced Malignant Tumors
Advanced Malignant Tumors
SUNHO（China）BioPharmaceutical CO., Ltd.25 enrolled1 locationNCT05991583
Recruiting
Phase 1Phase 2
A Phase I/II Study of LM-101 Injection in Patients With Advanced Malignant Tumors
Malignant Tumors
LaNova Medicines Limited139 enrolled5 locationsNCT05615974