MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease Clinical Trials

17 recruitingLast updated: June 18, 2026

There are 17 actively recruiting masld - metabolic dysfunction-associated steatotic liver disease clinical trials across 7 countries. Studies span Not Applicable, Phase 2. Top locations include San Francisco, California, United States, La Jolla, California, United States, Birmingham, Alabama, United States. Updated daily from ClinicalTrials.gov.


MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease Trials at a Glance

17 actively recruiting trials for masld - metabolic dysfunction-associated steatotic liver disease are listed on ClinicalTrialsFinder across 6 cities in 7 countries. The largest study group is Not Applicable with 7 trials, with the heaviest enrollment activity in San Francisco, La Jolla, and Birmingham. Lead sponsors running masld - metabolic dysfunction-associated steatotic liver disease studies include University of California, San Diego, University of California, San Francisco, and ContextVision AB.

Browse masld - metabolic dysfunction-associated steatotic liver disease trials by phase

Treatments under study

About MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease Clinical Trials

Looking for clinical trials for MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease? There are currently 17 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 117 of 17 trials

Recruiting
Not Applicable

UNMASK: UNveiling the Pathobiology of Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD) for the Discovery of Novel Therapeutics and biomarKers

MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease
Fundación Pública Andaluza para la gestión de la Investigación en Sevilla450 enrolled3 locationsNCT07652151
Recruiting
Not Applicable

EVOO and Metabolic Liver Health in MASLD

OverweightMASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease
Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis60 enrolled1 locationNCT07412444
Recruiting
Phase 2

A Study to Evaluate the Use of Resmetirom in Participants With MASLD and HIV

HIV (Human Immunodeficiency Virus)MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease
Naga P. Chalasani120 enrolled10 locationsNCT07143968
Recruiting
Phase 2

Investigation of the Efficacy of a Probiotic Mixture in Moderate Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A Mechanistic Trial

MASLD - Metabolic Dysfunction-Associated Steatotic Liver DiseaseFatty Liver Disease, NonalcoholicOverweight (BMI > 25)
AB Biotics, SA60 enrolled1 locationNCT07193927
Recruiting
Not Applicable

Effects of Normobaric Hypoxic Training in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

MASLD - Metabolic Dysfunction-Associated Steatotic Liver DiseaseNormobaric Hypoxia
University of Trieste20 enrolled1 locationNCT07073326
Recruiting

Accurate Point of Care Liver Disease Diagnostics (Phase 2)

MASLDNAFLD (Nonalcoholic Fatty Liver Disease)NAFLD+1 more
University of California, San Diego26 enrolled1 locationNCT07518784
Recruiting

Expanded Studies on the SCAPIS Stockholm Reexamination Cohort

Heart FailureCoronary Artery DiseaseOral Microbiota+9 more
Danderyd Hospital1,400 enrolled1 locationNCT07476703
Recruiting

Spleen Stiffness Measurement for the Detection of Advanced Fibrosis

MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease
Fondazione Policlinico Universitario Agostino Gemelli IRCCS500 enrolled1 locationNCT07440511
Recruiting

Quantitative Ultrasound to Assess Steatotic Liver Disease in Children

MASLDMASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease
University of California, San Diego120 enrolled1 locationNCT06706856
Recruiting
Not Applicable

Corazones Unidos Study

CVD - Cardiovascular DiseaseMASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease
University of Arizona45 enrolled1 locationNCT07298213
Recruiting
Not Applicable

Development of a Quantifiable Ultrasound Biomarker for Hepatic Steatosis

NAFLD - Non-Alcoholic Fatty Liver DiseaseMASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease
ContextVision AB110 enrolled1 locationNCT07270601
Recruiting
Phase 2

Effect of Ketone Esters on Liver Fat Content and Metabolic Function

ObesityOverweight (BMI > 25)MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease
Washington University School of Medicine40 enrolled1 locationNCT07097506
Recruiting
Not Applicable

Food Insecurity and MASLD: A Fruit and Vegetable Intervention Study

MASLD - Metabolic Dysfunction-Associated Steatotic Liver DiseaseFood Insecurity Among Children
University of California, San Francisco48 enrolled1 locationNCT07091539
Recruiting

Pediatric Metabolic Dysfunction-associated Steatotic Liver Disease and Food Insecurity

Food InsecurityMASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease
University of California, San Francisco160 enrolled1 locationNCT07090083
Recruiting
Not Applicable

The Impact of Pectin Supplementation on Systematic Inflammation Pathway, Gut Microbiome, and Metabolic Health in Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

MASLDNAFLD (Nonalcoholic Fatty Liver Disease)Metabolic Dysfunction-Associated Steatotic Liver Disease+5 more
University of Nottingham45 enrolled3 locationsNCT07093346
Recruiting

Development of a Non-invasive Screening Tool to Predict Metabolic Dysfunction-associated Steatotic Liver Disease

HealthyMASLDObesity and Obesity-related Medical Conditions+2 more
Richmond Research Institute2,000 enrolled1 locationNCT04873258
Recruiting

Cardiac Dysfunction in Patients with Fatty Liver Disease

Cardiac DiseaseNAFLDFatty Liver+1 more
Post Graduate Institute of Medical Education and Research, Chandigarh150 enrolled1 locationNCT06386094