Mental Health Clinical Trials

315 recruitingLast updated: July 17, 2026

There are 315 actively recruiting mental health clinical trials across 50 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 4. Top locations include New York, New York, United States, Chicago, Illinois, United States, Stockholm, Sweden. Updated daily from ClinicalTrials.gov.


Mental Health Trials at a Glance

315 actively recruiting trials for mental health are listed on ClinicalTrialsFinder across 6 cities in 50 countries. The largest study group is Not Applicable with 219 trials, with the heaviest enrollment activity in New York, Chicago, and Stockholm. Lead sponsors running mental health studies include Yale University, Karolinska Institutet, and Chinese University of Hong Kong.

Browse mental health trials by phase

Treatments under study

About Mental Health Clinical Trials

Looking for clinical trials for Mental Health? There are currently 193 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Mental Health trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Mental Health clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 315 trials

Recruiting
Not Applicable

A Toolkit to Improve Mental Health Treatment for Autistic Individuals

AutismMental Health Conditions
Florida International University18 enrolled2 locationsNCT07539519
Recruiting
Not Applicable

Preventing Vulnerable Child Syndrome in the NICU With Cognitive Behavioral Therapy (PreVNT Trial)

Premature InfantDevelopment, ChildParent-Child Relations+1 more
University of Texas Southwestern Medical Center100 enrolled1 locationNCT03906435
Recruiting
Not Applicable

Affirmative Psychotherapy for Sexual Minority Women's Mental and Behavioral Health

Mental Health IssueHeavy Drinking
Yale University274 enrolled1 locationNCT05509166
Recruiting
Not Applicable

Does Social Media Impact Adolescent Mental Health?

Mental Health
Georgetown University500 enrolled1 locationNCT06049888
Recruiting
Not Applicable

Pediatricians Building Resilience Through Early Identification for Toddler Well-Being

Mental Health
Northwestern University432 enrolled1 locationNCT07091240
Recruiting
Not Applicable

Family FINGER: Lifestyle Intervention Among Older Caregivers

Positive Mental Health
Tarja Välimäki100 enrolled1 locationNCT07627386
Recruiting
Not Applicable

Essential Coaching Postpartum: Evaluating a Parent-focused Postpartum Text Message Program in Nova Scotia

Postpartum StressMental HealthPostpartum Anxiety+3 more
IWK Health Centre332 enrolled1 locationNCT06996067
Recruiting
Not Applicable

Health Benefits of Dance Exercise

Metabolic HealthPhysical PerformanceMental Health
University of Thessaly40 enrolled1 locationNCT07615829
Recruiting

Mental Health After Dexmedetomidine for Electrical Storm

Mental Health
Ottawa Heart Institute Research Corporation70 enrolled1 locationNCT07368062
Recruiting
Not Applicable

Virtual Reality Lethal Means Safety Training

Suicide, AttemptedVeteransRural Health+3 more
The University of Texas at Arlington36 enrolled1 locationNCT07219355
Recruiting
Phase 2

Evaluating the Effectiveness of the Common Elements Treatment Approach (CETA) in Peru: Mechanisms of Individual and Intergenerational Change

DepressionMental HealthViolence+5 more
University of Notre Dame600 enrolled1 locationNCT07667738
Recruiting
Not Applicable

eCardiacRehab - a Hybrid Patient-Centered eHealth Programme

Comorbidities and Coexisting ConditionsOlder Adults (65 Years and Older)Mental Health+10 more
Haukeland University Hospital1,000 enrolled1 locationNCT07590635
Recruiting
Not Applicable

K-ORCA: Testing a Decision Support Tool and Group Process for Selecting Interventions

Child abuseDecision MakingDecision Making, Shared+9 more
Chestnut Health Systems80 enrolled1 locationNCT06375551
Recruiting
Not Applicable

Emotional Recovery Post-Stroke

StrokeMental Health Wellness 1
Medical University of South Carolina80 enrolled1 locationNCT06782321
Recruiting
Not Applicable

Hope Groups: Parenting and Mental Health Among Refugees in the Middle East

Mental HealthViolence Against Children
University of Oxford490 enrolled1 locationNCT07506421
Recruiting
Not Applicable

Improving Alcohol and Substance Use Care Access, Outcome, Equity During the Reproductive Years

Women's healthPregnancySexual Health+7 more
Emory University400 enrolled4 locationsNCT05910580
Recruiting
Not Applicable

Projecte Benestar 2026: Virtual Reality Program for Healthcare Workers

Mental Health IssueOccupational StressBurnout, Healthcare Workers
Badalona Serveis Assistencials100 enrolled2 locationsNCT07649733
Recruiting
Not Applicable

Experimental Evidence of the Impact of Parental Income on Child Mental Health and Neuroimmune Function

PsychopathologyAnxiety DisordersMental Disorders+3 more
Northwestern University500 enrolled1 locationNCT07641244
Recruiting

Overview of the Mental Health of Adolescents in Therapeutci, Educational and Pedagogical Facilities in France

Mental Health Disorder
University Hospital, Rouen200 enrolled2 locationsNCT06489912
Recruiting
Not Applicable

Transition Health and Resilience Through Valued Experiences (THRiVE) Pilot for Newly Separated Veterans

Suicidal IdeationMental HealthAlcohol Misuse+2 more
RTI International40 enrolled1 locationNCT06778278