Mental Health Clinical Trials

309 recruitingLast updated: June 19, 2026

There are 309 actively recruiting mental health clinical trials across 48 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 4. Top locations include New York, New York, United States, Chicago, Illinois, United States, Stockholm, Sweden. Updated daily from ClinicalTrials.gov.


Mental Health Trials at a Glance

309 actively recruiting trials for mental health are listed on ClinicalTrialsFinder across 6 cities in 48 countries. The largest study group is Not Applicable with 214 trials, with the heaviest enrollment activity in New York, Chicago, and Stockholm. Lead sponsors running mental health studies include Yale University, Karolinska Institutet, and Chinese University of Hong Kong.

Browse mental health trials by phase

Treatments under study

About Mental Health Clinical Trials

Looking for clinical trials for Mental Health? There are currently 190 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Mental Health trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Mental Health clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 309 trials

Recruiting
Not Applicable

Emotional Recovery Post-Stroke

StrokeMental Health Wellness 1
Medical University of South Carolina80 enrolled1 locationNCT06782321
Recruiting
Not Applicable

Improving Alcohol and Substance Use Care Access, Outcome, Equity During the Reproductive Years

Women's healthPregnancySexual Health+7 more
Emory University400 enrolled4 locationsNCT05910580
Recruiting
Not Applicable

Affirmative Psychotherapy for Sexual Minority Women's Mental and Behavioral Health

Mental Health IssueHeavy Drinking
Yale University274 enrolled1 locationNCT05509166
Recruiting
Not Applicable

Health Benefits of Dance Exercise

Metabolic HealthPhysical PerformanceMental Health
University of Thessaly40 enrolled1 locationNCT07615829
Recruiting
Not Applicable

Examining Whether Project Support Works

Child Mental HealthParent-Child RelationsParenting self-efficacy
Medical University of South Carolina100 enrolled1 locationNCT06963554
Recruiting

Overview of the Mental Health of Adolescents in Therapeutci, Educational and Pedagogical Facilities in France

Mental Health Disorder
University Hospital, Rouen200 enrolled2 locationsNCT06489912
Recruiting
Not Applicable

Transition Health and Resilience Through Valued Experiences (THRiVE) Pilot for Newly Separated Veterans

Suicidal IdeationMental HealthAlcohol Misuse+2 more
RTI International40 enrolled1 locationNCT06778278
Recruiting
Not Applicable

Experimental Evidence of the Impact of Parental Income on Child Mental Health and Neuroimmune Function

PsychopathologyAnxiety DisordersMental Disorders+3 more
Northwestern University500 enrolled1 locationNCT07641244
Recruiting
Not Applicable

Implementation Supports to Reduce Burnout in Therapists Delivering Child Trauma EBPs

Mental Health Issue
San Diego State University60 enrolled1 locationNCT04712461
Recruiting

Climate Anxiety in a Young Population at Risk of Suicide

Mental Health IssueAnxietyEnvironmental Exposure+1 more
Centre Hospitalier Esquirol108 enrolled1 locationNCT07305688
Recruiting
Not Applicable

Future Leaders Program: Testing a Youth Leadership, Engagement, and Mindfulness Program

Mental Health Wellness 1Adolescent Behavior Problem
Boston University Charles River Campus504 enrolled3 locationsNCT06736522
Recruiting
Not Applicable

Supporting Treatment Access and Recovery in COD

Mental Health DisorderOpioid-use Disorder
University of Massachusetts, Worcester1,000 enrolled5 locationsNCT05138614
Recruiting
Not Applicable

A Robotic Mental Health Simulation Intervention to Enhance Professional Identity, Interpersonal Communication Competence, and Emotional Intelligence Among Saudi Nursing Students: A Quasi-Experimental Study

Mental Health SimulationProfessional IdentityInterpersonal Communication Competence
Alexandria University80 enrolled1 locationNCT07627646
Recruiting
Not Applicable

The STIME Project: Intersectoral Prevention of Severe Youth Mental Health Difficulties

Mental health difficultiesPreventive Intervention
Center for Clinical Research and Prevention1,200 enrolled1 locationNCT07413887
Recruiting
Not Applicable

CanSOLVE 2.0 Theme 3.1 Mind the Gap - Dialectical Behavioural Therapy (DBT) Skills Training Program Pilot

HemodialysisMental HealthHealth-related Quality of Life+2 more
University of Manitoba35 enrolled1 locationNCT07628309
Recruiting
Not Applicable

Testing Multi-level Scale-Up Strategies: Ugandan School System

Mental Health
NYU Langone Health1,556 enrolled2 locationsNCT07466563
Recruiting
Not Applicable

Youth-for-Youth Mental Wellness Care and Action

Adolescent HealthMental Health LiteracyMental Well-being+2 more
Chinese University of Hong Kong18,000 enrolled2 locationsNCT06955195
Recruiting
Not Applicable

Testing the WeCare Intervention to Address Mental Health and Medication Adherence Challenges Among MSM in South Africa

HIV InfectionsMental Health
Emory University60 enrolled1 locationNCT07226323
Recruiting
Not Applicable

Culturally Adapted Strong Families Programme for Families Living in Gilgit Baltistan, Pakistan

Mental Health
Pakistan Institute of Living and Learning90 enrolled1 locationNCT05933850
Recruiting
Not Applicable

Harlem Strong Mental Health Coalition

Depression, AnxietyStress-related ProblemMental Health Wellness
City University of New York, School of Public Health700 enrolled2 locationsNCT05833555