Phase 2 Metastases Clinical Trials
118 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 118 trials
Recruiting
Phase 2
Stereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain Metastases
Breast CancerColorectal, CancerLung Cancer+13 more
Brigham and Women's Hospital134 enrolled2 locationsNCT04899908
Recruiting
Phase 1Phase 2
Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies
Colorectal, CancerColorectal CarcinomaNon-small Cell Lung Cancer+29 more
Institut de Recherches Internationales Servier554 enrolled27 locationsNCT05786924
Recruiting
Phase 1Phase 2
Safety of HRX215 in Patients After Minor and Major Liver Resection
Liver ResectionColorectal Carcinoma Liver Metastases
HepaRegeniX GmbH80 enrolled6 locationsNCT06638502
Recruiting
Phase 2
UCSD Image-Guided Cognitive-Sparing Radiosurgery for Brain Metastases
CancerBrain Metastases, AdultNeurocognitive Function
Jona Hattangadi-Gluth60 enrolled1 locationNCT04343157
Recruiting
Phase 2
A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the Brain
Lung CancerBrain Metastases, AdultBrain Metastases+3 more
Memorial Sloan Kettering Cancer Center62 enrolled7 locationsNCT05419076
Recruiting
Phase 2
Single- vs. Two-Fraction Spine Stereotactic Radiosurgery for the Treatment of Vertebral Metastases
Spine MetastasesSpine Stereotactic Radiosurgery (sSRS)
Case Comprehensive Cancer Center130 enrolled1 locationNCT04218617
Recruiting
Phase 2
Palliative Dose Escalated Radiation for Painful Non-Spine Bone Metastases and Painful Non-Bone Metas
Neoplasm MetastasesMetastases, Neoplasm
Rutgers, The State University of New Jersey124 enrolled7 locationsNCT05419518
Recruiting
Phase 1Phase 2
Hepzato Kit and Opdualag for Metastatic Melanoma and Liver Metastasis
Metastatic MelanomaLiver Metastases
University of Wisconsin, Madison15 enrolled1 locationNCT07281924
Recruiting
Phase 2
INTERACT Stomach-II
Peritoneal Metastases From Gastric Cancer
Erasmus Medical Center55 enrolled3 locationsNCT07133490
Recruiting
Phase 2
Avoiding Radiation Therapy Due to Intracranial Response to Chemotherapy, Targeted Therapy and/or Immuno-ONcology Therapy for Brain Metastases: Pilot Pragmatic Trial
Brain Metastases, AdultBrain Metastases From Non-small Cell Lung Cancer (NSCLC)
University of Vermont Medical Center45 enrolled1 locationNCT06974370
Recruiting
Phase 2
Trial of Relatlimab, Nivolumab, and Ipilimumab in Patients With Asymptomatic and Symptomatic Melanoma Brain Metastases
MelanomaBrain Metastases
Stanford University60 enrolled1 locationNCT06712927
Recruiting
Phase 2
Platform Study of Immunotherapy Combinations in Colorectal Cancer Liver Metastases
Colorectal, CancerLiver MetastasesColorectal Cancer Metastatic
Weill Medical College of Cornell University24 enrolled1 locationNCT06300463
Recruiting
Phase 2
Timely Integration of Palliative Care in Oncology Care for Patients Referred for Palliative Radiotherapy on Bone Metastases: A Randomized Trial
RadiotherapyBone Metastases in Subjects With Advanced Cancer
Roxanne Gal246 enrolled5 locationsNCT06805396
Recruiting
Phase 2
Immune Checkpoint Inhibitors Intrathecal Injection in Patients With Leptomeningeal Metastases in NSCLC
NSCLC Associated With Leptomeningeal Metastases
West China Hospital17 enrolled1 locationNCT06132698
Recruiting
Phase 2
BITS-TO-HCC Study: HAIC+Iparomlimab/Tuvonralimab + Bevacizumab + SBRT for BCLC-C HCC With PVTT and/or Oligometastases
Hepatocellular CarcinomaRadiotherapyImmunotherapy+3 more
Shandong Cancer Hospital and Institute54 enrolled1 locationNCT07062055
Recruiting
Phase 2
A Study of Intensity-Modulated Pleural Radiation Therapy (IMPRINT) in People With Thymic Cancer That Has Spread to the Lining of the Lungs and Chest
Thymic MalignanciesPleural Metastases
Memorial Sloan Kettering Cancer Center36 enrolled7 locationsNCT05354570
Recruiting
Phase 2
The Application of Pressured Intraperitoneal Aerosol Chemotherapy (PIPAC) for Peritoneal Surface Malignancies
Peritoneal Metastases
The University of Hong Kong60 enrolled1 locationNCT06367270
Recruiting
Phase 2
Efficacy and Safety of SPH4336 in Combination With Endocrine Therapy in Breast Cancer Patients With Brain Metastases.
Breast Cancer Brain Metastases
Shanghai Pharmaceuticals Holding Co., Ltd52 enrolled25 locationsNCT05872347
Recruiting
Phase 2
Optimizing Neurocognition With Whole Brain Radiation Therapy (WBRT) Using Upfront Pulsed Reduced Dose-Rate (PRDR) Technique
Brain Metastases
Medical College of Wisconsin53 enrolled2 locationsNCT05045950
Recruiting
Phase 2
LM-302 and S-1 Plus Intraperitoneal Paclitaxel With or Without Cadonilimab for Claudin 18.2-positive Gastric or Gastroesophageal Junction Adenocarcinoma With Peritoneal Metastasis: a Prospective, Exploratory Study
Peritoneal Metastases From Gastric CancerGastric Cancer Stage IVGastric or Esophagogastric Junction Adenocarcinoma
Ruijin Hospital74 enrolled1 locationNCT07556640