Metastases Clinical Trials

5 recruiting

Metastases Trials at a Glance

297 actively recruiting trials for metastases are listed on ClinicalTrialsFinder across 6 cities in 45 countries. The largest study group is Phase 2 with 98 trials, with the heaviest enrollment activity in Houston, New York, and Toronto. Lead sponsors running metastases studies include M.D. Anderson Cancer Center, Fudan University, and Memorial Sloan Kettering Cancer Center.

Browse metastases trials by phase

Treatments under study

About Metastases Clinical Trials

Looking for clinical trials for Metastases? There are currently 5 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Metastases trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Metastases clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 297 trials

Recruiting

Evaluation of Cell Changes in Blood and Tissue in Cancers of the Lung, Esophagus and Lung Lining

Thoracic CancersLung Cancer NOSMalignant Pleural Mesotheliomas NOS+2 more
National Cancer Institute (NCI)1,559 enrolled1 locationNCT00242723
Recruiting
Phase 2

The Application of Pressured Intraperitoneal Aerosol Chemotherapy (PIPAC) for Peritoneal Surface Malignancies

Peritoneal Metastases
The University of Hong Kong60 enrolled1 locationNCT06367270
Recruiting
Phase 1

In Vivo Lung Perfusion (IVLP) for Colorectal Cancer Metastatic to Lung

Colorectal Cancer MetastaticLung Metastases
University Health Network, Toronto10 enrolled1 locationNCT05611034
Recruiting
Not Applicable

Incremental Value of Magnetic Resonance Imaging in Selection of Pancreatic Cancer Patients for Surgery

Pancreatic CancerLiver MetastasesPancreatic Neoplasm
University of Aarhus200 enrolled3 locationsNCT05428358
Recruiting
Phase 2

Optimizing Neurocognition With Whole Brain Radiation Therapy (WBRT) Using Upfront Pulsed Reduced Dose-Rate (PRDR) Technique

Brain Metastases
Medical College of Wisconsin53 enrolled2 locationsNCT05045950
Recruiting
Phase 2

LM-302 and S-1 Plus Intraperitoneal Paclitaxel With or Without Cadonilimab for Claudin 18.2-positive Gastric or Gastroesophageal Junction Adenocarcinoma With Peritoneal Metastasis: a Prospective, Exploratory Study

Peritoneal Metastases From Gastric CancerGastric Cancer Stage IVGastric or Esophagogastric Junction Adenocarcinoma
Ruijin Hospital74 enrolled1 locationNCT07556640
Recruiting
Not Applicable

Preoperative vs Postoperative Hypofractionated Radiosurgery for Patients With Large Brain Metastases

Brain Metastases, Adult
Istituto Clinico Humanitas146 enrolled9 locationsNCT05545007
Recruiting
Not Applicable

Motor Eloquent Navigated Transcranial Magnetic Stimulation for Radiosurgery Planning

Metastases to Brain
Insel Gruppe AG, University Hospital Bern30 enrolled1 locationNCT07415668
Recruiting
Phase 1Phase 2

Selinexor With ICE Chemotherapy in Secondary Central Nervous System Involving B-cell Non-Hodgkin Lymphoma

CNS MetastasesB-cell Lymphoma RecurrentB-cell Lymphoma Refractory
Samsung Medical Center37 enrolled2 locationsNCT06552559
Recruiting

Registry for Bone Metastases

Bone Metastases
Memorial Sloan Kettering Cancer Center500 enrolled7 locationsNCT07391410
Recruiting
Phase 1

Assess Use of 18F-Fluciclovine for Patients With Large Brain Metastases Treated With Staged Stereotactic Radiosurgery

Brain Metastases, AdultBrain MetastasesBrain Cancer
Baptist Health South Florida20 enrolled1 locationNCT04689048
Recruiting
Phase 2

Inflammation in Primary and Secondary Malignancies of the Central Nervous System Using [C-11]-CS1P1

Brain MetastasesCentral Nervous System Cancer
Washington University School of Medicine104 enrolled1 locationNCT07462507
Recruiting
Phase 3

Post-Op Pain Control for Prophylactic Intramedullary Nailing.

PainBone MetastasesOpioid Use+2 more
St. Louis University60 enrolled1 locationNCT03823534
Recruiting
Phase 1Phase 2

Safety of HRX215 in Patients After Minor and Major Liver Resection

Liver ResectionColorectal Carcinoma Liver Metastases
HepaRegeniX GmbH80 enrolled4 locationsNCT06638502
Recruiting
Phase 2

AK104 Plus Radiotherapy Combined With Standard Therapy Versus Standard Therapy as First-Line Treatment for pMMR/MSS CRLM (APSOC)

Colorectal Cancer Liver Metastases (CRLM)
Fudan University73 enrolled1 locationNCT07544784
Recruiting
Phase 2

NTS-WBRT in Brain Metastases

Brain Metastases
Massachusetts General Hospital41 enrolled1 locationNCT05013892
Recruiting
Phase 2

EXCLAIM: Exploring Combined Local and Systemic Approaches In Brain Metastasis: a Multi-cohort Randomized Phase II Study Evaluating Initial Response to Systemic Therapy and Subsequent Integration of Stereotactic Radiosurgery in Patients With Low-risk Brain Metastases and Central Nervous System-active

Brain Metastases
M.D. Anderson Cancer Center316 enrolled1 locationNCT06649058
Recruiting
Phase 2

Phase II Study of Pembrolizumab in Combination With Lenvatinib in Patients With TNBC, NSCLC, and Other Tumor Types and Brain Metastases

Brain MetastasesTumor
M.D. Anderson Cancer Center104 enrolled1 locationNCT05064280
Recruiting
Phase 3

Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases

Brain Metastases
Canadian Cancer Trials Group206 enrolled86 locationsNCT03550391
Recruiting
Not Applicable

Pilot Randomized Study for Treatment Volume De-Escalation for Spinal Metastases With Stereotactic Body Radiation Therapy

Metastases to Bone
IRCCS Sacro Cuore Don Calabria di Negrar100 enrolled1 locationNCT07538024