Phase 3 Metastases Clinical Trials
24 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 24 trials
Recruiting
Phase 3
Post-Op Pain Control for Prophylactic Intramedullary Nailing.
PainBone MetastasesOpioid Use+2 more
St. Louis University60 enrolled1 locationNCT03823534
Recruiting
Phase 3
Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases
Brain Metastases
Canadian Cancer Trials Group206 enrolled86 locationsNCT03550391
Recruiting
Phase 3
Bevacizumab Plus FSRT Versus Hippocampus-Avoidant WBRT in Lung Adenocarcinoma With Extensive Brain Metastases
Brain MetastasesLung AdenocarcinomaWhole-Brain Radiotherapy+2 more
Sun Yat-sen University220 enrolled3 locationsNCT07481786
Recruiting
Phase 3
Evaluation of the Safety and Efficacy of Abenacianine (VGT-309) to Identify Cancer in Subjects Undergoing Surgery for Cancer in the Lung
Lung CancerLung Metastases
Vergent Bioscience, Inc.132 enrolled6 locationsNCT07499674
Recruiting
Phase 2Phase 3
Tissue Analysis After Tumor Ablation for Liver Metastases Leading to Immediate Retreatment
Liver Metastases
Memorial Sloan Kettering Cancer Center200 enrolled1 locationNCT04143516
Recruiting
Phase 3
Ultra-high Dose Radiation for Liver Metastasis Using MR-guided TReatment With Stereotactic Ablative Single-fraction
Liver Metastases
University Health Network, Toronto114 enrolled1 locationNCT06362395
Recruiting
Phase 3
A Phase III Randomized Trial Comparing Stereotactic Body Radiation Therapy (SBRT) vs Conventional Palliative Radiation Therapy for Painful Bone Metastases
Bone Metastases
M.D. Anderson Cancer Center220 enrolled1 locationNCT06065449
Recruiting
Phase 3
Intraperitoneal Paclitaxel and Systemic Therapy Versus Systemic Therapy Alone in Gastric Cancer Patients With Peritoneal Metastasis
Gastric Cancer Peritoneal Metastases
Magnus Nilsson262 enrolled5 locationsNCT07304271
Recruiting
Phase 3
FSRT Combines With Bevacizumab for Multiple Brain Metastases in Lung Adenocarcinoma
Multiple Brain Metastases in Lung Adenocarcinoma
Sun Yat-Sen University Cancer Center258 enrolled1 locationNCT07058428
Recruiting
Phase 3
Observation or Upfront Cranial RT in Oncogene Mutated NSCLC With Asymptomatic BM: A Phase III RCT
Asymptomatic Brain MetastasesDriver Mutation Positive Non-small Cell Lung Cancer
Tata Memorial Hospital190 enrolled1 locationNCT05236946
Recruiting
Phase 3
Corticodependent or Corticoresistant Brain Radionecrosis After Radiotherapy for Brain Metastases
Brain MetastasesRadionecrosis of Brain
Institut Cancerologie de l'Ouest84 enrolled10 locationsNCT06471465
Recruiting
Phase 3
Comparing SingLe- Vs Multi-Fraction Spine STereotActic Radiosurgery in Spinal Metastases
Spinal Metastases
Stanford University274 enrolled1 locationNCT06173401
Recruiting
Phase 3
Induction Treatment for Initially Unresectable Colorectal Liver Metastases: Combined Hepatic Arterial Infusion Pump Therapy With Systemic Therapy
Liver MetastasesColorectal NeoplasmsFloxuridine+1 more
The Netherlands Cancer Institute306 enrolled1 locationNCT06857773
Recruiting
Phase 3
PHP in Combination With IPI1/NIVO3 Compared to IPI3/NIVO1 Only in Patients With Uveal Melanoma Liver Metastases
Liver MetastasesUveal Melanoma
Vastra Gotaland Region40 enrolled6 locationsNCT06519266
Recruiting
Phase 3
Improved Recovery by Iron Following Surgery With Blood Loss, the IRIS-trial
Liver CancerSurgeryLiver Metastases+2 more
Jon Unosson338 enrolled1 locationNCT05744219
Not Yet Recruiting
Phase 2Phase 3
PREDICTORG: A Multicentre Personalised Medicine Approach in the Treatment of Colorectal Peritoneal Metastases
Colorectal Peritoneal Metastases
Peter MacCallum Cancer Centre235 enrolled7 locationsACTRN12624001230549
Recruiting
Phase 3
Short Versus Long-term Androgen Deprivation Therapy With Salvage Radiotherapy in Prostate Cancer. URONCOR 0624
Prostate CancerAndrogen Deprivation TherapyBiochemical Recurrence+2 more
Instituto de Investigación en Oncología Radioterápica - Fundación Española de Oncología Radioterápic534 enrolled17 locationsNCT05781217
Recruiting
Phase 3
Regorafenib Combined With Irinotecan Drug-Eluting Beads for Colorectal Cancer Liver Metastases
RegorafenibColorectal Cancer Liver Metastases
Sun Yat-sen University126 enrolled1 locationNCT05794971
Recruiting
Phase 3
Early or Delayed Intervention of Brain Radiotherapy Combined With Almonertinib in EGFR Mutated NSCLC With Brain Metastases
Brain MetastasesRadiotherapyEGFR Activating Mutation
Sun Yat-sen University232 enrolled1 locationNCT05768490
Recruiting
Phase 3
Fractionated Stereotactic Radiotherapy vs. Single Session Radiosurgery in Patients With Larger Brain Metastases
Cerebral Metastases of Solid Cancers
University of Erlangen-Nürnberg Medical School382 enrolled13 locationsNCT03697343