Phase 3 Metastases Clinical Trials
34 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 34 trials
Recruiting
Phase 3
Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases
Brain Metastases
Canadian Cancer Trials Group206 enrolled86 locationsNCT03550391
Recruiting
Phase 3
Evaluation of the Safety and Efficacy of Abenacianine (VGT-309) to Identify Cancer in Subjects Undergoing Surgery for Cancer in the Lung
Lung CancerLung Metastases
Vergent Bioscience, Inc.132 enrolled9 locationsNCT07499674
Recruiting
Phase 3
Post-Op Pain Control for Prophylactic Intramedullary Nailing.
PainBone MetastasesOpioid Use+2 more
St. Louis University60 enrolled1 locationNCT03823534
Recruiting
Phase 2Phase 3
Neoadjuvant Serplulimab & Bevacizumab With FOLFOX vs. FOLFOX Alone in RAS/BRAF WT, pMMR/MSS CRC Patients
Colorectal, CancerLiver Metastases
Sun Yat-sen University156 enrolled1 locationNCT06280495
Recruiting
Phase 3
Bevacizumab Plus FSRT Versus Hippocampus-Avoidant WBRT in Lung Adenocarcinoma With Extensive Brain Metastases
Brain MetastasesLung AdenocarcinomaWhole-Brain Radiotherapy+2 more
Sun Yat-sen University220 enrolled3 locationsNCT07481786
Recruiting
Phase 2Phase 3
Tissue Analysis After Tumor Ablation for Liver Metastases Leading to Immediate Retreatment
Liver Metastases
Memorial Sloan Kettering Cancer Center200 enrolled1 locationNCT04143516
Recruiting
Phase 3
Ultra-high Dose Radiation for Liver Metastasis Using MR-guided TReatment With Stereotactic Ablative Single-fraction
Liver Metastases
University Health Network, Toronto114 enrolled1 locationNCT06362395
Recruiting
Phase 3
Adjuvant FOLFIRI Based-chemotherapy After Resection of CLM Responding to Preoperative FOLFIRI
Colorectal, CancerColorectal Liver Metastases
Assistance Publique - Hôpitaux de Paris254 enrolled1 locationNCT06501482
Recruiting
Phase 3
A Phase III Randomized Trial Comparing Stereotactic Body Radiation Therapy (SBRT) vs Conventional Palliative Radiation Therapy for Painful Bone Metastases
Bone Metastases
M.D. Anderson Cancer Center220 enrolled1 locationNCT06065449
Recruiting
Phase 3
Intraperitoneal Paclitaxel and Systemic Therapy Versus Systemic Therapy Alone in Gastric Cancer Patients With Peritoneal Metastasis
Gastric Cancer Peritoneal Metastases
Magnus Nilsson262 enrolled5 locationsNCT07304271
Recruiting
Phase 3
FSRT Combines With Bevacizumab for Multiple Brain Metastases in Lung Adenocarcinoma
Multiple Brain Metastases in Lung Adenocarcinoma
Sun Yat-Sen University Cancer Center258 enrolled1 locationNCT07058428
Recruiting
Phase 3
Observation or Upfront Cranial RT in Oncogene Mutated NSCLC With Asymptomatic BM: A Phase III RCT
Asymptomatic Brain MetastasesDriver Mutation Positive Non-small Cell Lung Cancer
Tata Memorial Hospital190 enrolled1 locationNCT05236946
Recruiting
Phase 3
Corticodependent or Corticoresistant Brain Radionecrosis After Radiotherapy for Brain Metastases
Brain MetastasesRadionecrosis of Brain
Institut Cancerologie de l'Ouest84 enrolled10 locationsNCT06471465
Recruiting
Phase 3
Comparing SingLe- Vs Multi-Fraction Spine STereotActic Radiosurgery in Spinal Metastases
Spinal Metastases
Stanford University274 enrolled1 locationNCT06173401
Recruiting
Phase 3
SRS/SRT/Hypo-RT Versus HA-WBRT for No More Than 10 Brain Metastases in SCLC
Brain MetastasesStereotactic RadiotherapySmall Cell Lung Cancer+3 more
Cancer Institute and Hospital, Chinese Academy of Medical Sciences340 enrolled1 locationNCT06457906
Recruiting
Phase 3
Efficacy of Hyperthermic Intraperitoneal Chemotherapy
Colorectal, CancerPeritoneal Metastases
Uppsala University213 enrolled5 locationsNCT04861558
Recruiting
Phase 3
SBRT + PD-1 Monoclonal Antibody in Unresectable Colorectal Liver Metastases
Colorectal, CancerLiver Metastases
Jun Huang24 enrolled1 locationNCT06794086
Recruiting
Phase 3
Induction Treatment for Initially Unresectable Colorectal Liver Metastases: Combined Hepatic Arterial Infusion Pump Therapy With Systemic Therapy
Liver MetastasesColorectal NeoplasmsFloxuridine+1 more
The Netherlands Cancer Institute306 enrolled1 locationNCT06857773
Recruiting
Phase 3
Conversion Therapy of RAS/BRAF Wild-Type Colorectal Cancer Patients With Initially Unresectable Liver Metastases
Colorectal, CancerLiver Metastases
Fudan University508 enrolled1 locationNCT04687631
Recruiting
Phase 3
PHP in Combination With IPI1/NIVO3 Compared to IPI3/NIVO1 Only in Patients With Uveal Melanoma Liver Metastases
Liver MetastasesUveal Melanoma
Vastra Gotaland Region40 enrolled6 locationsNCT06519266