Methamphetamine Dependence Clinical Trials

10 recruitingLast updated: June 18, 2026

There are 10 actively recruiting methamphetamine dependence clinical trials across 3 countries. Studies span Phase 2, Not Applicable, Phase 3, Early Phase 1. Top locations include Portland, Oregon, United States, Montreal, Quebec, Canada, Dresden, Germany. Updated daily from ClinicalTrials.gov.


Methamphetamine Dependence Trials at a Glance

10 actively recruiting trials for methamphetamine dependence are listed on ClinicalTrialsFinder across 6 cities in 3 countries. The largest study group is Phase 2 with 4 trials, with the heaviest enrollment activity in Portland, Montreal, and Dresden. Lead sponsors running methamphetamine dependence studies include Centre hospitalier de l'Université de Montréal (CHUM), Montana State University, and Evon Medics LLC.

Browse methamphetamine dependence trials by phase

Treatments under study

About Methamphetamine Dependence Clinical Trials

Looking for clinical trials for Methamphetamine Dependence? There are currently 11 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Methamphetamine Dependence trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Methamphetamine Dependence clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 110 of 10 trials

Recruiting
Phase 2

Glutide for Ending Methamphetamine

Methamphetamine Dependence
San Francisco Department of Public Health162 enrolled1 locationNCT07204249
Recruiting
Phase 3

Trial of Naltrexone/Bupropion for the Treatment of Methamphetamine Use Disorder

methamphetamine abuseMethamphetamine Dependence
National Institute on Drug Abuse (NIDA)360 enrolled11 locationsNCT06233799
Recruiting
Phase 2

Feasibility of Long-term, High-dose Stimulant for Methamphetamine Use Disorder

methamphetamine abuseSubstance AbuseMethamphetamine Dependence+2 more
Centre hospitalier de l'Université de Montréal (CHUM)80 enrolled1 locationNCT06788587
Recruiting
Not Applicable

Encouraging Abstinence Behavior in a Drug Epidemic: Optimizing Dynamic Incentives

methamphetamine abuseOpioid UseOpioid-use Disorder+4 more
Wake Forest University Health Sciences600 enrolled2 locationsNCT04927143
Recruiting
Phase 2

Clinical Trial of High Dose Lisdexamfetamine and Contingency Management in MA Users

methamphetamine abuseMethamphetamine DependenceAddiction+1 more
Centre hospitalier de l'Université de Montréal (CHUM)440 enrolled4 locationsNCT05854667
Recruiting

Role of Pavlovian Mechanisms for Control Over Substance Use

AlcoholismSubstance Use DisordersCannabis Use Disorder+4 more
Technische Universität Dresden200 enrolled1 locationNCT06701487
Recruiting
Phase 2

Enhanced Digital-Chemosensory-Based Olfactory Training for Remote Management of Substance Use Disorders

Substance Use DisordersOpioid-use DisorderAlcohol Use Disorder+2 more
Evon Medics LLC300 enrolled3 locationsNCT06434818
Recruiting
Early Phase 1

PRevention Of Methamphetamine Use Among Postpartum Women Trial (PROMPT)

Methamphetamine DependencePostpartum Abstinence
University of Utah40 enrolled1 locationNCT05128071
Recruiting
Not Applicable

rTMS for Craving in Methamphetamine Use Disorder

methamphetamine abuseSubstance Use DisordersTranscranial Magnetic Stimulation+3 more
Oregon Health and Science University50 enrolled1 locationNCT03470480
Recruiting
Phase 3

Creatine for Depressed Male and Female Methamphetamine Users

DepressionAnxietyMethamphetamine Dependence
Montana State University29 enrolled1 locationNCT02568878