Phase 4 MS Clinical Trials

34 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 34 trials

Recruiting
Phase 4

Comparison of Ocular Lubricants in People With Symptoms of Dry Eye

Dry Eye Symptoms
University of Waterloo100 enrolled1 locationNCT07451184
Recruiting
Phase 4

Safety and Immunogenicity of the Live Attenuated Tetravalent Butantan-Dengue Vaccine in Autoimmune Rheumatic Diseases

Psoriatic Arthritis (PsA)Rheumatoid Arthritis (RA)Systemic Lupus Erythematosus (SLE)+9 more
University of Sao Paulo General Hospital477 enrolled2 locationsNCT07087912
Recruiting
Phase 4

The Psychiatric and Cognitive Phenotypes in Velocardiofacial Syndrome

Williams SyndromeFragile X SyndromeVelocardiofacial Syndrome
The Chaim Sheba Medical Center400 enrolled1 locationNCT00768820
Recruiting
Phase 4

Ublituximab (Briumvi) for Early Forms of Relapsing Multiple Sclerosis

Multiple SclerosisMultiple Sclerosis (MS) - Relapsing-remitting
Northwestern University40 enrolled1 locationNCT07225361
Recruiting
Phase 4

Erector Spinae Block for Thoracic Surgery

Thoracic CancerPulmonary CancerThoracic Neoplasms+2 more
George Washington University70 enrolled1 locationNCT05521789
Recruiting
Phase 4

Fractional CO2 Laser-assisted Delivery of Hyaluronic Acid, Ascorbic Acid and Sodium DNA For Enhancing Facial Skin Quality in Individuals Over the Age of 30

Photo-aged SkinSkin Quality ImprovementDrug Delivery Systems
Instituto de Oftalmología Fundación Conde de Valenciana30 enrolled1 locationNCT07376148
Recruiting
Phase 4

Prospective Multicenter Real-world Study of Surufatinib in Patients With Advanced Neuroendocrine Neoplasms

Neuroendocrine TumorsNeuroendocrine Neoplasms
Shanghai Zhongshan Hospital350 enrolled4 locationsNCT07272512
Recruiting
Phase 4

Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients

ConfusionCognitive DysfunctionMolecular Mechanisms of Pharmacological Action+14 more
Sunnybrook Health Sciences Centre2,400 enrolled8 locationsNCT04289142
Recruiting
Phase 4

DPYD Pharmacogenomics and Fluoropyrimidine (FP) Dose-Adjustment

Breast NeoplasmsColorectal NeoplasmsHead and Neck Neoplasms+1 more
Rutgers, The State University of New Jersey100 enrolled12 locationsNCT07158164
Recruiting
Phase 4

Fenofibrate Role in the Prophylaxis From Peripheral Neuropathy Induced by Bortezomib, Lenalidomide and Dexamethasone (VRd) Protocol in the Treatment of Patients With Multiple Myeloma (MM)

Peripheral NeuropathyMultiple Myeloma, Neoplasms
Tanta University44 enrolled2 locationsNCT07025005
Recruiting
Phase 4

HighCycle Study: Acetazolamide, High Altitude and Plasma Volume

WomenHigh Altitude EffectsHigh Altitude Hypoxia+2 more
Centre d'Expertise sur l'Altitude EXALT270 enrolled1 locationNCT07118462
Recruiting
Phase 4

Imaging Biomarkers of FOG Response to DBS

Deep Brain StimulationFreezing of Gait Symptoms in Parkinson's Disease
Medical University of South Carolina54 enrolled1 locationNCT06951906
Recruiting
Phase 4

Dose Individualization of Antineoplastic Drugs and Anti-Infective Drug in Children With Hematoplastic Disease

Hematological Neoplasms
Wei Zhao1,500 enrolled2 locationsNCT03844360
Recruiting
Phase 4

Sacubitril/Valsartan in PriMAry preventIoN of the Cardiotoxicity of Systematic breaST canceR trEAtMent (MAINSTREAM)

Breast CancerHeart FailureBreast Diseases+10 more
Silesian Centre for Heart Diseases600 enrolled4 locationsNCT05465031
Recruiting
Phase 4

18F-Fluciclovine PET/CT Impact on Predicting Clinical Outcome of 177Lu-PSMA-617 Therapy in Patients With Prostate Cancer

NeoplasmsMetastatic Prostate CancerNeoplasms by Site+8 more
VA Greater Los Angeles Healthcare System15 enrolled1 locationNCT06706921
Recruiting
Phase 4

Acute and Long-Term Antidepressant Treatment Success in Adolescents With Anxiety (AtLAS-A)

AnxietyDepressive Symptoms
University of Cincinnati60 enrolled1 locationNCT04245436
Recruiting
Phase 4

TES RCT Fleet Enema vs Oral Mechanical Bowel Prep

SurgeryColorectal Neoplasms
Nova Scotia Health Authority66 enrolled1 locationNCT05148494
Completed
Phase 4

Effect of probenecid or ibuprofen on flucloxacillin exposure in healthy adults

Other infections require flucloxacillin for treatmentMethicillin-susceptible Staphylococcus aureus (MSSA) infection
University of Melbourne20 enrolled1 locationACTRN12623001155684
Recruiting
Phase 4

Comprehensive Analysis of Spatial, Temporal and Molecular Patterns of Ribociclib Efficacy and Resistance in Advanced Breast Cancer Patients

Breast CancerBreast Cancer FemaleBreast Neoplasms+2 more
Institut fuer Frauengesundheit1,000 enrolled52 locationsNCT05452213
Recruiting
Phase 4

The Efficacy and Safety of Silodosin Singly or Combined With Ningmitai Capsules in the Treatment of Benign Prostatic Hyperplasia

Benign Prostatic Hyperplasia With Lower Urinary Tract Symptoms
Xintian Pharmaceutical312 enrolled8 locationsNCT05551221