Phase 2 Myopathy Clinical Trials
39 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 39 trials
Recruiting
Phase 2
Venous Ethanol for Ventricular Tachycardia
Ventricular TachycardiaIschemic Cardiomyopathy
The Methodist Hospital Research Institute156 enrolled1 locationNCT05511246
Recruiting
Phase 2
Study of LX2006 Gene Therapy in Friedreich Ataxia Cardiomyopathy
Friedreich AtaxiaCardiomyopathy, Secondary
Lexeo Therapeutics26 enrolled1 locationNCT07721025
Recruiting
Phase 2Phase 3
RESET-Myositis: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Idiopathic Inflammatory Myopathy or Juvenile Idiopathic Inflammatory Myopathy
DermatomyositisIdiopathic Inflammatory MyopathyAnti-synthetase Syndrome+5 more
Cabaletta Bio74 enrolled35 locationsNCT06154252
Recruiting
Phase 1Phase 2
Study of ASP2957 in Male Participants With X-linked Myotubular Myopathy Who Need Ventilators
X-linked Myotubular Myopathy
Astellas Gene Therapies9 enrolled4 locationsNCT07052929
Recruiting
Phase 2
A Trial to Compare Treatment With Surlorian (ARM210, S48168) to Placebo in Effects on Muscle Strength and Safety in Adults With Autosomal Dominant RYR1-related Myopathy
Autosomal Dominant RYR1-Related Myopathy
RyCarma Therapeutics, Inc.28 enrolled9 locationsNCT07560020
Recruiting
Phase 1Phase 2
Safety and Efficacy of FAP iCDC in End-stage Dilated Cardiomyopathy
Heart FailureDilated Cardiomyopathy (DCM)
Second Affiliated Hospital, School of Medicine, Zhejiang University43 enrolled1 locationNCT06902896
Recruiting
Phase 1Phase 2
An AAV Gene Therapy Trial of AFTX-201 in Adults With BAG3-Associated Dilated Cardiomyopathy (DCM)
Dilated Cardiomyopathy (DCM)BAG3 Mutation Associated Dilated Cardiomyopathy
Affinia Therapeutics22 enrolled3 locationsNCT07426419
Recruiting
Phase 1Phase 2
A Study With NVC-001 in Patients With LMNA-related Dilated Cardiomyopathy (SUNBEAM-LMNA)
LMNA-Related Dilated Cardiomyopathy
Nuevocor Pte. Ltd.21 enrolled6 locationsNCT07606274
Recruiting
Phase 2Phase 3
A Study of the Efficacy and Safety of Danicamtiv in Participants With Symptomatic Genetic and Familial Dilated Cardiomyopathy
Symptomatic Genetic Dilated Cardiomyopathy
Kardigan, Inc.332 enrolled56 locationsNCT07210723
Recruiting
Phase 2
18F-mFBG Imaging for Myocardial Sympathetic Innervation
Heart FailureIschemic CardiomyopathyICD Patients
Innervate Radiopharmaceuticals LLC (Formerly: Illumina Radiopharmaceuticals LLC)20 enrolled1 locationNCT06965621
Recruiting
Phase 2
A Study to Evaluate the Efficacy and Safety of Concomitant Use of Eplontersen and ALXN2220 Compared With Eplontersen and Placebo for Adults Participants With ATTR-CM
Transthyretin Amyloid Cardiomyopathy (ATTR CM)
AstraZeneca326 enrolled78 locationsNCT07608354
Recruiting
Phase 1Phase 2
ALXN2350 in Adult Participants With BAG3-Associated Dilated Cardiomyopathy
BAG3 Mutation Associated Dilated Cardiomyopathy
Alexion Pharmaceuticals, Inc.6 enrolled10 locationsNCT07218887
Recruiting
Phase 2
A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy
Non-obstructive Hypertrophic Cardiomyopathy
Imbria Pharmaceuticals, Inc.165 enrolled67 locationsNCT07023614
Recruiting
Phase 2
Cyclosporine In Takotsubo Syndrome
Takotsubo Cardiomyopathy
University Hospital Heidelberg204 enrolled24 locationsNCT05946772
Recruiting
Phase 2
Evaluation of the Possible Safety and Efficacy of Dapagliflozin in the Prophylaxis of Doxorubicin-Induced Cardiotoxicity
Breast CancerDoxorubicin Induced Cardiomyopathy
Tanta University46 enrolled1 locationNCT06427226
Recruiting
Phase 2Phase 3
A Study to Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM).
PediatricSymptomatic Obstructive Hypertrophic Cardiomyopathy
Cytokinetics55 enrolled38 locationsNCT06412666
Recruiting
Phase 2
Administration of Allogeneic-MSC in Patients With Non-Ischemic Dilated Cardiomyopathy
Non-ischemic Dilated Cardiomyopathy
Joshua M Hare136 enrolled4 locationsNCT04476901
Recruiting
Phase 2
Ademetionine in Obstructive Hypertrophic Cardiomyopathy
Obstructive Hypertrophic Cardiomyopathy (oHCM)
China National Center for Cardiovascular Diseases44 enrolled3 locationsNCT07367724
Recruiting
Phase 1Phase 2
Multi-center, Open-label, Single-ascending Dose Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCM
Hypertrophic Cardiomyopathy
Tenaya Therapeutics30 enrolled10 locationsNCT05836259
Recruiting
Phase 2
Targeted Therapy With Glycogen Synthase Kinase-3 Inhibition for Arrhythmogenic Cardiomyopathy
Arrhythmogenic CardiomyopathyArrhythmogenic Right Ventricular Cardiomyopathy
Hamilton Health Sciences Corporation120 enrolled17 locationsNCT06174220