Phase 2 Myopathy Clinical Trials
32 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 32 trials
Recruiting
Phase 2
A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy
Non-obstructive Hypertrophic Cardiomyopathy
Imbria Pharmaceuticals, Inc.165 enrolled67 locationsNCT07023614
Recruiting
Phase 2Phase 3
RESET-Myositis: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Idiopathic Inflammatory Myopathy or Juvenile Idiopathic Inflammatory Myopathy
DermatomyositisIdiopathic Inflammatory MyopathyAnti-synthetase Syndrome+5 more
Cabaletta Bio74 enrolled35 locationsNCT06154252
Recruiting
Phase 2Phase 3
A Study of the Efficacy and Safety of Danicamtiv in Participants With Symptomatic Genetic and Familial Dilated Cardiomyopathy
Symptomatic Genetic Dilated Cardiomyopathy
Kardigan, Inc.332 enrolled33 locationsNCT07210723
Recruiting
Phase 2
Cyclosporine In Takotsubo Syndrome
Takotsubo Cardiomyopathy
University Hospital Heidelberg204 enrolled24 locationsNCT05946772
Recruiting
Phase 2
Evaluation of the Possible Safety and Efficacy of Dapagliflozin in the Prophylaxis of Doxorubicin-Induced Cardiotoxicity
Breast CancerDoxorubicin Induced Cardiomyopathy
Tanta University46 enrolled1 locationNCT06427226
Recruiting
Phase 1Phase 2
Study of ASP2957 in Male Participants With X-linked Myotubular Myopathy Who Need Ventilators
X-linked Myotubular Myopathy
Astellas Gene Therapies9 enrolled4 locationsNCT07052929
Recruiting
Phase 2Phase 3
A Study to Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM).
PediatricSymptomatic Obstructive Hypertrophic Cardiomyopathy
Cytokinetics55 enrolled38 locationsNCT06412666
Recruiting
Phase 2
Venous Ethanol for Ventricular Tachycardia
Ventricular TachycardiaIschemic Cardiomyopathy
The Methodist Hospital Research Institute156 enrolled1 locationNCT05511246
Recruiting
Phase 2
Administration of Allogeneic-MSC in Patients With Non-Ischemic Dilated Cardiomyopathy
Non-ischemic Dilated Cardiomyopathy
Joshua M Hare136 enrolled4 locationsNCT04476901
Recruiting
Phase 2
Ademetionine in Obstructive Hypertrophic Cardiomyopathy
Obstructive Hypertrophic Cardiomyopathy (oHCM)
China National Center for Cardiovascular Diseases44 enrolled3 locationsNCT07367724
Recruiting
Phase 1Phase 2
Multi-center, Open-label, Single-ascending Dose Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCM
Hypertrophic Cardiomyopathy
Tenaya Therapeutics30 enrolled10 locationsNCT05836259
Recruiting
Phase 2
Targeted Therapy With Glycogen Synthase Kinase-3 Inhibition for Arrhythmogenic Cardiomyopathy
Arrhythmogenic CardiomyopathyArrhythmogenic Right Ventricular Cardiomyopathy
Hamilton Health Sciences Corporation120 enrolled17 locationsNCT06174220
Recruiting
Phase 1Phase 2
Application of [68Ga]Ga-NI-FAPI-04 PET/CT Imaging in Fibroblast Activation Protein Related Diseases
TumorCardiovascular DiseasesPulmonary Fibrosis+3 more
Peking Union Medical College Hospital30 enrolled1 locationNCT07464132
Recruiting
Phase 1Phase 2
ALXN2350 in Adult Participants With BAG3-Associated Dilated Cardiomyopathy
BAG3 Mutation Associated Dilated Cardiomyopathy
Alexion Pharmaceuticals, Inc.6 enrolled7 locationsNCT07218887
Recruiting
Phase 2
PET Myocardial Fatty-acid Metabolic Imaging With XTR003 Injection and 18F-FDG to Assess Myocardial Viability in Ischemic Cardiomyopathy
Heart FailureIschemic Cardiomyopathy
Sinotau Pharmaceutical Group40 enrolled3 locationsNCT07443696
Recruiting
Phase 2
The MIGHT Trial - An Exploratory Clinical Trial of IVIG in Anti-HMGCR Immune Mediated Necrotizing Myopathy
Anti-3-hydroxy-3-methylglutaryl-CoA Reductase (HMGCR) Immune-Mediated Necrotizing Myopathy
University of Alabama at Birmingham12 enrolled5 locationsNCT06599697
Recruiting
Phase 1Phase 2
A Phase I/II Clinical Trial of Intramyocardial Injection of HucMSCs for the Treatment of Chronic Heart Failure
Chronic Heart FailureCoronary Artery Bypass Grafting (CABG)Chronic Ischemic Cardiomyopathy
Tasly Pharmaceutical Group Co., Ltd51 enrolled4 locationsNCT07265349
Recruiting
Phase 2
A Clinical Study to Evaluate the Long-term Safety of HRS-1893 in Hypertrophic Cardiomyopathy
Hypertrophic Cardiomyopathy
Shandong Suncadia Medicine Co., Ltd.300 enrolled1 locationNCT07021963
Recruiting
Phase 1Phase 2
Annatto-derived GG for Statin-associated Myopathy
Myopathy; Primary
Texas Tech University Health Sciences Center95 enrolled1 locationNCT05312424
Recruiting
Phase 2
A Study to Assess TTI-0102 vs Placebo in MELAS Patients
Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-like Episodes (MELAS)MELAS Syndrome
Thiogenesis Therapeutics, Inc.12 enrolled2 locationsNCT06644534