Early Phase 1 NEC Clinical Trials
19 recruitingEarly Phase 1
What is a Early Phase 1 trial?
Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.
Showing 1–19 of 19 trials
Recruiting
Early Phase 1
Exploratory Clinical Study on the Safety and Efficacy of Anti- CD19/BCMA CAR-NK Cell Injection for the Treatment of Refractory Pediatric Rheumatic Diseases
Systemic Lupus Erythematosus (SLE)Rheumatic DiseasesPediatric Rheumatological Condition (i.e., Arthritis, SLE, Kawasaki's Disaese)+1 more
The Children's Hospital of Zhejiang University School of Medicine36 enrolled1 locationNCT07490041
Recruiting
Early Phase 1
Exploratory Clinical Study of cCTL in Combination With Immunotherapy for Advanced Gynecologic Malignancies
Advanced Gynecological Cancers
Obstetrics & Gynecology Hospital of Fudan University20 enrolled1 locationNCT07434284
Recruiting
Early Phase 1
[177Lu]Lu-AKIR001 First-in-human Study
Thyroid Gland Anaplastic CarcinomaPoorly Differentiated Thyroid CarcinomaCancer Head and Neck+3 more
Karolinska University Hospital15 enrolled1 locationNCT06639191
Recruiting
Early Phase 1
Drug Screening Using Novel IMD in Salivary and Head and Neck Cancers
Head and Neck CancerSquamous Cell Carcinoma of Head and NeckSalivary Gland Cancer+1 more
Brigham and Women's Hospital30 enrolled2 locationsNCT05553782
Recruiting
Early Phase 1
Intraoral Hypothermia Device for Preserving Taste During Radiation
Head and Neck CancerRadiation TherapyTaste Dysfunction
Henry Ford Health System15 enrolled1 locationNCT06579248
Recruiting
Early Phase 1
PET-imaging of Two Vartumabs in Patients With Solid Tumors
Breast CancerBladder CarcinomaEsophageal Carcinoma+11 more
Var2 Pharmaceuticals32 enrolled1 locationNCT06645808
Recruiting
Early Phase 1
Comparison of 89Zr Panitumumab and (18)F-Fluorodeoxyglucose to Identify Head and Neck Squamous Cell Carcinoma
Head and Neck Squamous Cell Carcinoma
University of Alabama at Birmingham14 enrolled1 locationNCT05183048
Recruiting
Early Phase 1
A Study of GC201 TIL in Advanced Gynecologic Tumors (10hospital)
Treatment Side EffectsEffects of ImmunotherapyAdvanced Gynecologic Tumors+1 more
Shanghai Juncell Therapeutics50 enrolled1 locationNCT05098171
Recruiting
Early Phase 1
Comparing an Investigational Scan (F-18 NaF PET/CT) to Standard of Care Imaging (F-18 FDG PET/CT) for Evaluating Vascular Complications in Patients Receiving Radiation Therapy for Head and Neck Cancer
Head and Neck Squamous Cell CarcinomaClinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Stage III Hypopharyngeal Carcinoma AJCC v8+13 more
Emory University20 enrolled1 locationNCT06914999
Recruiting
Early Phase 1
A Phase 0 Multicenter Study of the Pharmacodynamic Effects of Intratumoral Microdose Administration of PBA-0111 in Patients With Solid Tumors
Head and Neck Squamous Cell CarcinomaSoft Tissue Sarcoma Adult
Pure Biologics S.A.12 enrolled1 locationNCT06700070
Recruiting
Early Phase 1
Pembrolizumab, INCB081776, and Radiation Therapy for Head and Neck Squamous Cell Carcinoma
Head and Neck Squamous Cell Carcinoma
University of Wisconsin, Madison12 enrolled1 locationNCT06308913
Recruiting
Early Phase 1
Clinical Study of GT201 in the Treatment of Advanced Gynecological Tumors
Adult Gynecological Tumors
Grit Biotechnology26 enrolled1 locationNCT06834542
Recruiting
Early Phase 1
PBI-MST-01 (NCT04541108) Substudy AZN-05: Intratumoral Microdosing of Rilvegostomig, Volrustomig, Sabestomig, and AZD9592 in HNSCC
Head and Neck Squamous Cell Carcinoma
Presage Biosciences15 enrolled7 locationsNCT06366451
Recruiting
Early Phase 1
PrePhage - Faecal Bacteriophage Transfer for Enhanced Gastrointestinal Tract Maturation in Preterm Infants
Necrotizing EnterocolitisMicrobial Substitution
Rigshospitalet, Denmark20 enrolled1 locationNCT05272579
Recruiting
Early Phase 1
Image-Based, In-Vivo Assessment of Tumor Hypoxia to Guide Hypoxia-Driven Adaptive Radiation Therapy
Head and Neck Squamous Cell CarcinomaBrain Metastases
Vanderbilt-Ingram Cancer Center48 enrolled1 locationNCT05996432
Recruiting
Early Phase 1
Evaluation of the Efficacy and Safety of Methylprednisolone Combined With the JAK Inhibitors in the Treatment of Toxic Epidermal Necrolysis
Toxic Epidermal Necrolysis
Peng Zhang30 enrolled1 locationNCT06119490
Recruiting
Early Phase 1
A Clinical Study on Oncolytic Virus Injection (R130 OV) for the Treatment of Advanced Solid Tumors
Breast CancerSarcomaLung Cancer+7 more
Shanghai Yunying Medical Technology20 enrolled1 locationNCT05961111
Recruiting
Early Phase 1
A Clinical Study on Oncolytic Virus Injection (R130 OV) for the Treatment of Relapsed/Refractory Head and Neck Cancer
Esophageal CancerHead and Neck CancerLaryngeal Cancer+4 more
Shanghai Yunying Medical Technology9 enrolled1 locationNCT05830240
Not Yet Recruiting
Early Phase 1
A Pilot Study of Cetuximab Radiolabelled with Gallium-68, Lutetium-177 or Rhenium-188 as a Novel Radioimmunotherapy for Advanced Head and Neck Cancer: A New Adjunct to Multi-modality Treatment.
Head and Neck Squamous Cell Carcinoma
Dr Timothy Marr30 enrolled1 locationACTRN12614000491662