Phase 1 Nephropathy Clinical Trials
14 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–14 of 14 trials
Recruiting
Phase 1
A Phase I Clinical Study of Recombinant Humanized Anti-CD20(B-lymphocyte Antigen CD20) Monoclonal Antibody Subcutaneous Injection in the Treatment of Primary Membranous Nephropathy
Primary Membranous Nephropathy
Shanghai Jiaolian Drug Research and Development Co., Ltd52 enrolled6 locationsNCT05668403
Recruiting
Phase 1Phase 2
A Study of MIL116 in Healthy Participants and Patients With IgA Nephropathy.
Immunoglobulin A Nephropathy
Beijing Mabworks Biotech Co., Ltd.130 enrolled1 locationNCT07375758
Recruiting
Phase 1Phase 2
PS-002 for the Treatment of IgA Nephropathy in Adults
Immunoglobulin A (IgA) Nephropathy
Purespring Therapeutics Limited32 enrolled11 locationsNCT07182227
Recruiting
Phase 1
Study of BHV-1400 in IgA Nephropathy
IgA Nephropathy
Biohaven Therapeutics Ltd.20 enrolled12 locationsNCT07054684
Recruiting
Phase 1Phase 2
A Phase 1/2 Study of NKX019 in Subjects With Autoimmune Disease (Ntrust-1)
Lupus NephritisPrimary Membranous Nephropathy
Nkarta, Inc.96 enrolled16 locationsNCT06557265
Recruiting
Phase 1Phase 2
Safety and Efficacy of Allogeneic Umbilical Cord Mesenchymal Stem Cell Therapy in Diabetic Nephropathy Patients: A Clinical Trial
Diabetic Nephropathy Type 2
PT. Prodia Stem Cell Indonesia10 enrolled1 locationNCT07396155
Recruiting
Phase 1
CAR T-cell Therapy Targeting CD19 and BCMA in Patients With B Cell Mediated Autoimmune Disease
IgA Nephropathy (IgAN)Autoimmune DiseasesSystemic Sclerosis (SSc)+3 more
The Children's Hospital of Zhejiang University School of Medicine15 enrolled1 locationNCT07305116
Recruiting
Phase 1
Safety and Efficacy of CD19 Chimeric Antigen Receptor T-Cell (CAR-T) in the Treatment of Refractory Membranous Nephropathy
Refractory Membranous Nephropathy
The First Affiliated Hospital of Air Force Medicial University5 enrolled1 locationNCT07266181
Recruiting
Phase 1
Study of YK012 in Primary Membranous Nephropathy
Primary Membranous Nephropathy
Excyte Biopharma Ltd72 enrolled1 locationNCT06982729
Recruiting
Phase 1
The BCMA/CD19 Dual Targeted CAR-T Cell in Participants With Autoimmune Kidney Diseases
ANCA-associated VasculitisIgG4-Related DiseasesLupus Nephritis+1 more
Nanjing University School of Medicine24 enrolled1 locationNCT06285279
Recruiting
Phase 1
Evaluate The Efficacy, Safety, Pharmacokinetics And Pharmacodynamics Of EVER001
Primary Membranous Nephropathy
Everest Medicines (China) Co.,Ltd.30 enrolled19 locationsNCT05800873
Not Yet Recruiting
Phase 1
A healthy volunteer study to test a new drug, CNT2130
Diabetic Nephropathy
Centaurus Therapeutics Pty Ltd48 enrolled1 locationACTRN12625000446460
Recruiting
Phase 1
A First in Human Study to Evaluate Safety, Tolerability, Pharmacology of HS-10390 in Healthy Subjects
Focal Segmental GlomerulosclerosisIgA Nephropathy
Hansoh BioMedical R&D Company84 enrolled1 locationNCT05942625
Completed
Phase 1
VIS649-102: A study assessing single doses of VIS649, in healthy adults.
Immunoglobulin A Nephropathy
IQVIA RDS Pty Limited48 enrolled1 locationACTRN12620001352998