Phase 2 Neuroblastoma Clinical Trials
41 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 41 trials
Recruiting
Phase 2
Iodine I 131 Metaiodobenzylguanidine in Treating Patients With Recurrent, Progressive, or Refractory Neuroblastoma or Malignant Pheochromocytoma or Paraganglioma
PheochromocytomaNeuroblastoma
Memorial Sloan Kettering Cancer Center200 enrolled1 locationNCT00107289
Recruiting
Phase 2
A Study of a Vaccine in Combination With β-glucan and GM-CSF in People With Neuroblastoma
Neuroblastoma
Memorial Sloan Kettering Cancer Center286 enrolled1 locationNCT04936529
Recruiting
Phase 1Phase 2
Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors
OsteosarcomaEwing SarcomaNeuroblastoma+10 more
University of Florida27 enrolled1 locationNCT06625190
Recruiting
Phase 1Phase 2
Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)
Diffuse Large B Cell LymphomaEwing SarcomaNeuroblastoma+2 more
Merck Sharp & Dohme LLC90 enrolled66 locationsNCT06395103
Recruiting
Phase 2
A Study of a Vaccine in Combination With Beta-glucan in People With Neuroblastoma
NeuroblastomaHigh Risk NeuroblastomaMetastatic Neuroblastoma
Memorial Sloan Kettering Cancer Center94 enrolled7 locationsNCT06057948
Recruiting
Phase 1Phase 2
Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas
OsteosarcomaEwing SarcomaNeuroblastoma+3 more
Milton S. Hershey Medical Center289 enrolled6 locationsNCT06465199
Recruiting
Phase 1Phase 2
Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors
OsteosarcomaEwing SarcomaNeuroblastoma+2 more
Milton S. Hershey Medical Center104 enrolled20 locationsNCT06541262
Recruiting
Phase 2
Tipifarnib and Naxitamab for Relapsed/Refractory Neuroblastoma
Neuroblastoma
Giselle Sholler98 enrolled11 locationsNCT06540963
Recruiting
Phase 1Phase 2
Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors
Ovarian CarcinomaColorectal CarcinomaMelanoma+19 more
Children's Oncology Group147 enrolled21 locationsNCT04851119
Recruiting
Phase 2
Pediatric Precision Laboratory Advanced Neuroblastoma Therapy
Neuroblastoma
Giselle Sholler500 enrolled27 locationsNCT02559778
Recruiting
Phase 2
Naxitamab for High-Risk Neuroblastoma Patients With Primary Refractory Disease or Incomplete Response to Salvage Treatment in Bone and/or Bone Marrow
Neuroblastoma
Y-mAbs Therapeutics122 enrolled26 locationsNCT03363373
Recruiting
Phase 2
A Phase II Study With a Safety Run-In of the Addition of N-803 to a Chemoimmunotherapy Backbone for the Treatment of Patients With Relapsed or Refractory Neuroblastoma
Neuroblastoma Recurrent
St. Jude Children's Research Hospital54 enrolled1 locationNCT07085338
Recruiting
Phase 2
N10: A Study of Reduced Chemotherapy and Monoclonal Antibody (mAb)-Based Therapy in Children With Neuroblastoma
NeuroblastomaHigh Risk NeuroblastomaChildhood Neuroblastoma
Memorial Sloan Kettering Cancer Center45 enrolled1 locationNCT06528496
Recruiting
Phase 1Phase 2
SPEARHEAD-3 Pediatric Study
OsteosarcomaSynovial SarcomaMalignant Peripheral Nerve Sheath Tumor (MPNST)+1 more
USWM CT, LLC20 enrolled10 locationsNCT05642455
Recruiting
Phase 1Phase 2
Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma
Recurrent Malignant Solid NeoplasmRefractory Malignant Solid NeoplasmRecurrent Solid Tumor+19 more
St. Jude Children's Research Hospital90 enrolled10 locationsNCT04901702
Recruiting
Phase 1Phase 2
Apatinib Mesylate Combined With IT Regimen for the Treatment of Recurrent or Refractory Pediatric Neuroblastoma: A Single-arm, Phase I/II，Multi-center, Clinical Study.
Neuroblastoma
Sun Yat-sen University125 enrolled1 locationNCT05027386
Recruiting
Phase 1Phase 2
An Imaging Study of Anti-GD2-800CW in Patients With Neuroblastoma
Neuroblastoma
Princess Maxima Center for Pediatric Oncology22 enrolled1 locationNCT07399821
Recruiting
Phase 2
Eflornithine (DFMO) and Etoposide for Relapsed/Refractory Neuroblastoma
Neuroblastoma
Giselle Sholler131 enrolled31 locationsNCT04301843
Recruiting
Phase 2
Naxitamab Added to Induction for Newly Diagnosed High-Risk Neuroblastoma
Neuroblastoma
Giselle Sholler93 enrolled23 locationsNCT05489887
Recruiting
Phase 2
Neuroblastoma Maintenance Therapy Trial
Neuroblastoma
Giselle Sholler441 enrolled49 locationsNCT02679144