Non-Cardiac Surgery Clinical Trials

15 recruitingLast updated: June 18, 2026

There are 15 actively recruiting non-cardiac surgery clinical trials across 11 countries. Studies span Not Applicable, Phase 3, Phase 4. Top locations include Ankara, Turkey (Türkiye), Beijing, Beijing Municipality, China, Bern, Switzerland. Updated daily from ClinicalTrials.gov.


Non-Cardiac Surgery Trials at a Glance

15 actively recruiting trials for non-cardiac surgery are listed on ClinicalTrialsFinder across 6 cities in 11 countries. The largest study group is Not Applicable with 7 trials, with the heaviest enrollment activity in Ankara, Beijing, and Bern. Lead sponsors running non-cardiac surgery studies include Beijing Tsinghua Chang Gung Hospital, Centre Hospitalier Universitaire, Amiens, and Ankara City Hospital Bilkent.

Browse non-cardiac surgery trials by phase

Treatments under study

About Non-Cardiac Surgery Clinical Trials

Looking for clinical trials for Non-Cardiac Surgery? There are currently 7 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Non-Cardiac Surgery trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Non-Cardiac Surgery clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 115 of 15 trials

Recruiting
Phase 4

LANdiolol to Avoid TAchycardia in Patients at Risk for Cardiovascular Events Undergoing Major Non-cardiac Surgery

myocardial injury after non-cardiac surgeryAutonomic DysfunctionCardiovascular (CV) Risk+3 more
Insel Gruppe AG, University Hospital Bern114 enrolled1 locationNCT07168421
Recruiting
Not Applicable

Continuous Vital Sign Monitoring Versus Routine Spot-checks in Patients After Non-cardiac Surgery

Non-Cardiac SurgeryPost-operative complicationsAnesthesiology+2 more
Universitätsklinikum Hamburg-Eppendorf264 enrolled1 locationNCT07385092
Recruiting
Not Applicable

Submaximal Cardiopulmonary Exercise Testing for Detection of Myocardial Injury After Noncardiac Surgery

myocardial injury after non-cardiac surgeryPreoperative PeriodSubmaximal Exercise Performance
Yale University61 enrolled1 locationNCT06474754
Recruiting
Phase 3

Noradrenaline Versus Standard Blood Pressure Management for Perioperative Hypotension in Non-cardiac Surgery

Non-Cardiac SurgeryIntraoperative hypotensionBlood Pressure Management
Jagiellonian University750 enrolled5 locationsNCT06885268
Recruiting

Myocardial Injury After Noncardiac Surgery (MINS) in Lumbar Surgery Patients

Non-Cardiac SurgeryAnesthesiaMYOCARD INFARCTUS+1 more
Ankara City Hospital Bilkent180 enrolled1 locationNCT07081009
Recruiting
Phase 3

Lung Ultrasound-guided Hemodynamic Optimization

Non-Cardiac SurgeryLung UltrasoundGoal Directed Therapy
Centre Hospitalier Universitaire, Amiens350 enrolled1 locationNCT05481723
Recruiting
Not Applicable

Individualized Versus Conventional Perioperative Blood Pressure Management

Major non-cardiac surgery
Seoul National University Hospital1,896 enrolled5 locationsNCT06225453
Recruiting

Differential Impact of Pringle and Portal Vein Occlusion on Myocardial Injury After Non-Cardiac Surgeries.

myocardial injury after non-cardiac surgeryIschemia Reperfusion Injury
Beijing Tsinghua Chang Gung Hospital800 enrolled1 locationNCT06895798
Recruiting
Not Applicable

Effect of Low-dose EsketaMine on dElirium in High-risk Elderly Patients uNdergoing elecTive Surgery (ELEMENT)

Non-Cardiac SurgeryPain, PostoperativeCognitive Dysfunction+4 more
Nanfang Hospital, Southern Medical University1,670 enrolled6 locationsNCT06817239
Recruiting
Not Applicable

Non-invasive Measurement of the Hypotension Prediction Index for the Reduction of Intraoperative Hypotension

Intraoperative hypotensionmyocardial injury after non-cardiac surgeryAcute Kidney Injury
University of Giessen150 enrolled1 locationNCT06291714
Recruiting
Not Applicable

A Study of Huperzine A Injection in Reducing Postoperative Delirium in Elderly Patients Undergoing Non-cardiac Surgery

Non-Cardiac SurgeryPost Operative DeliriumDelirium in Old Age+1 more
Second Affiliated Hospital of Wenzhou Medical University40 enrolled1 locationNCT05242419
Recruiting
Not Applicable

The Effects of General Versus Spinal Anesthesia on Postoperative Myocardial Injury

myocardial injury after non-cardiac surgeryHypotension During SurgeryAnesthesia General+1 more
Sisli Hamidiye Etfal Training and Research Hospital100 enrolled1 locationNCT06343259
Recruiting
Phase 3

Managing Delirium with FLUvoxamine treatment in Non-Cardiac Surgical patients: a feasibility trial

Non-Cardiac SurgeryDelirium
Royal Prince Alfred Hosptial46 enrolled2 locationsACTRN12622000862741
Recruiting

Look before you Leap: A randomized controlled trial of the impact on length of hospital stay of ECHOcardiography Goal-directed Ultrasound Informed Decision-making for Elderly patients undergoing emergency noncardiac surgery - The ECHOGUIDE III trial

Patients aged over 65 years unplanned admission to hospital due to acute illness and scheduled for emergency non-cardiac surgery (thoracic, arterial vascular, general including colorectal and hepatobiliary, ear nose throat, faciomaxillary, neurosurgery and major orthopaedic surgery).
Royal Melbourne Hospital350 enrolled2 locationsACTRN12619000116123
Recruiting

Study of risk assessment to reduce complications in patients following non cardiac surgery

Cardiac complications following major non-cardiac surgery
Professor T Marwick600 enrolled1 locationACTRN12607000056493