Phase 1 Obese Clinical Trials
13 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–13 of 13 trials
Recruiting
Phase 1
A Study of SYNT-101 to Test Safety, Tolerability and Pharmacodynamics of SYNT-101 in Healthy and Overweight Adults
HealthyOverweight and Obese Adults
Syntis Bio64 enrolled1 locationNCT07307274
Recruiting
Phase 1Phase 2
A Study to Evaluate ALN-4324 in Overweight to Obese Healthy Volunteers and in Overweight to Obese Patients With T2DM
Type 2 Diabetes Mellitus (T2DM)Obese or Overweight Healthy Volunteers
Alnylam Pharmaceuticals144 enrolled20 locationsNCT06845202
Recruiting
Phase 1
A Study Looking at How Weekly Injections of Two Hormones - GIP and Amylin - Affect Stomach-related Side Effects in People Who Are Overweight or Obese
OverweightObese
Novo Nordisk A/S100 enrolled1 locationNCT07411560
Recruiting
Phase 1
A 2-part, Phase 1b Clinical Study Designed to Evaluate the Safety, PK, and Efficacy of CRB-913 in Participants With Obesity
Obese But Otherwise Healthy Participants
Corbus Pharmaceuticals Inc.252 enrolled15 locationsNCT07310901
Recruiting
Phase 1
A Single Ascending Dose Study of HM17321 in Healthy Adult Participants
ObesityObese
Hanmi Pharmaceutical Company Limited40 enrolled1 locationNCT07219589
Recruiting
Phase 1Phase 2
Pilot Testing a Novel Approach to Pediatric Obesity Treatment
Obese AdolescentsOverweight Adolescents
Texas Tech University30 enrolled1 locationNCT06755827
Recruiting
Phase 1
Study of ALV-100 to Assess Safety, Tolerability, and PK/PD in Overweight/Obese Participants With or Without T2D
Overweight or Obese AdultsOverweight or Obese, Type 2 Diabetes
Alveus Therapeutics, Inc.180 enrolled1 locationNCT07399678
Recruiting
Phase 1
A Study of XW003 Injection in Chinese Adolescents With Obesity
ObesityObese Adolescents
Hangzhou Sciwind Biosciences Co., Ltd.48 enrolled1 locationNCT07143227
Recruiting
Phase 1
Evaluate LAE102 in Healthy and Overweight/Obese Subjects
Overweight and Obese Volunteers
Laekna Limited160 enrolled1 locationNCT06493084
Recruiting
Phase 1
A Study of BGM0504 Tablets in Healthy and Non-diabetic Overweight or Obese Chinese Subjects
HealthyNon-diabetic Overweight or Obese
BrightGene Bio-Medical Technology Co., Ltd.75 enrolled1 locationNCT07239973
Recruiting
Phase 1
Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of BGM0504 Tablets in Non-diabetic Overweight or Obese Adult Subjects
Non-diabetic Overweight or Obese
BrightGene Bio-Medical Technology Co., Ltd.80 enrolled1 locationNCT07166081
Recruiting
Phase 1Phase 2
A Phase I/IIa Clinical Study to Assess the Single and Multiple Ascending Doses of MDR-001 Tablets in Healthy Participants and Obese/ Overweight Participants
Overweight and Obese Volunteers
MindRank AI Ltd131 enrolled1 locationNCT06778850
Terminated
Phase 1
A Double-Blind, Randomized, Placebo-Controlled Phase I Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Doses of CT-868 in Healthy Overweight/Obese Participants and in Patients with Type 2 Diabetes Mellitus
ObeseType 2 Diabetes Mellitus
Carmot Therapeutics103 enrolled3 locationsACTRN12618001988246