Phase 1 Obstructive Sleep Apnea Clinical Trials

11 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 111 of 11 trials

Recruiting
Phase 1Phase 2

Cerebral Blood Flow and Ventilatory Responses During Sleep in Normoxia and Intermittent Hypoxia

Hypoxia, BrainBlood PressureStroke+5 more
University of Calgary12 enrolled1 locationNCT03255408
Recruiting
Phase 1Phase 2

Atomoxetine and DAW2022 on OSA Severity

Obstructive Sleep Apnea
Brigham and Women's Hospital18 enrolled1 locationNCT05350215
Recruiting
Phase 1

Vascular Endothelial Dysfunction in Sleep Apnea

Obstructive Sleep Apnea of Adult
Columbia University110 enrolled1 locationNCT05289063
Recruiting
Phase 1Phase 2

Low-Tech Treatments for Obstructive Sleep Apnea

Traumatic Brain Injury (TBI)Obstructive Sleep Apnea (OSA)
Uniformed Services University of the Health Sciences60 enrolled1 locationNCT07301710
Recruiting
Phase 1Phase 2

Intermittent Hypoxia-initiated Plasticity in Humans: A Multi-pronged Therapeutic Approach to Treat Sleep Apnea and Overlapping Co-morbidities

Obstructive Sleep Apnea
VA Office of Research and Development60 enrolled1 locationNCT05558501
Recruiting
Phase 1Phase 2

DRonabinol Treatment of OSA

Obstructive Sleep Apnea
VA Office of Research and Development120 enrolled1 locationNCT06477952
Recruiting
Phase 1

Exploring the Use of Phototherapy to Improve CPAP Compliance

Obstructive Sleep Apnea
University of Alberta30 enrolled1 locationNCT06960161
Recruiting
Phase 1Phase 2

Trazodone on OSA Endotypes

Obstructive Sleep Apnea
Brigham and Women's Hospital18 enrolled1 locationNCT06286189
Recruiting
Phase 1

Is Obstructive Sleep Apnea Important in the Development of Alzheimer's Disease?

Obstructive Sleep ApneaAlzheimer DiseaseSleep Apnea+1 more
University of California, San Diego260 enrolled1 locationNCT05094271
Recruiting
Phase 1Phase 2

Rescue Pharmacotherapy for OSA

Obstructive Sleep Apnea
Brigham and Women's Hospital70 enrolled1 locationNCT05293600
Recruiting
Phase 1Phase 2

Pharmacological Activation of HMN for OSA Aim 2

Obstructive Sleep Apnea
Brigham and Women's Hospital16 enrolled1 locationNCT03858751