Phase 2 Opioid-use Disorder Clinical Trials
32 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 32 trials
Recruiting
Phase 2
A Study of Brenipatide in Participants With Opioid Use Disorder
Opioid-use Disorder
Eli Lilly and Company465 enrolled57 locationsNCT07420283
Recruiting
Phase 2
Psilocybin on Brain Mechanisms of Motivation in OUD
Opioid-use Disorder
University of Pennsylvania24 enrolled1 locationNCT06810310
Recruiting
Phase 2
Evaluation of Tirzepatide as an Adjunct to Buprenorphine for the Treatment of Opioid Use Disorder
Opioid-use DisorderOpioid Use Disorder, ModerateOpioid Use Disorder, Severe
T. John Winhusen, PhD310 enrolled9 locationsNCT06651177
Recruiting
Phase 2Phase 3
Efficacy of Buprenorphine and XR-Naltrexone Combination for Relapse Prevention in Opioid Use Disorder
Opioid-use Disorder
New York State Psychiatric Institute180 enrolled2 locationsNCT05011266
Recruiting
Phase 2
Evaluating Buspirone to Treat Opioid Withdrawal
AnxietyOpioid-use DisorderOpioid Withdrawal+1 more
University of Maryland, Baltimore100 enrolled1 locationNCT05511909
Recruiting
Phase 1Phase 2
Clinical Trials of Multivalent Opioid Vaccine Components
Opioid-use Disorder
New York State Psychiatric Institute45 enrolled2 locationsNCT04458545
Recruiting
Phase 2
Extended-release Buprenorphine as a Novel Low-dose Induction Strategy
Opioid-use Disorder
Brigham and Women's Hospital30 enrolled1 locationNCT06441604
Recruiting
Phase 2
Remotely Observed Methadone Evaluation II
Opioid-use Disorder
Sonara Health100 enrolled1 locationNCT06338280
Recruiting
Phase 2
MDMA for Co-occurring PTSD and OUD After Childbirth
Stress Disorders, Post-TraumaticOpioid-use Disorder
University of New Mexico15 enrolled1 locationNCT05219175
Recruiting
Phase 2
Ketamine for Opioid Use Disorder
Opioid-use Disorder
University of Maryland, Baltimore50 enrolled1 locationNCT06943859
Recruiting
Phase 2
E-Cigarettes for Harm Reduction in Smokers With Opioid Use Disorder
Opioid-use DisorderCigarette Smoking
NYU Langone Health302 enrolled2 locationsNCT05722561
Recruiting
Phase 1Phase 2
A Bundled Intervention
Opioid-use DisorderOpioid Overdose
University of Alabama at Birmingham190 enrolled1 locationNCT06593093
Recruiting
Phase 2Phase 3
Divided or Single Exposure (DOSE) Study
Chronic PainOpioid-use DisorderMethadone
University of Maryland, Baltimore150 enrolled1 locationNCT05459402
Recruiting
Phase 2
Psilocybin for Opioid Use Disorder (OUD)
Opioid-use Disorder
NYU Langone Health480 enrolled5 locationsNCT06796062
Recruiting
Phase 2
Combined THC and CBD for OUD and Chronic Pain
Chronic PainOpioid-use Disorder
Yale University147 enrolled1 locationNCT06544291
Recruiting
Phase 2
Wellcome Leap Psilocybin for OUD
Opioid-use Disorder
Anna Rose Childress, Ph.D.36 enrolled1 locationNCT06786325
Recruiting
Phase 2Phase 3
Identifying Optimal Buprenorphine Dosing for Opioid Use Disorder Treatment and Prevention of Overdose
Opioid-use Disorder
Rhode Island Hospital250 enrolled1 locationNCT06316830
Recruiting
Phase 2
Semaglutide for Helping Opioid Recovery
Opioid-use Disorder
Brigham and Women's Hospital46 enrolled1 locationNCT06639464
Recruiting
Phase 2
Assessing a Clinically-meaningful Opioid Withdrawal Phenotype
Opioid-use DisorderOpioid WithdrawalOpioid Craving
University of Maryland, Baltimore60 enrolled1 locationNCT05027919
Recruiting
Phase 2
Rapid Outpatient Low-dose Initiation of Buprenorphine for OUD With Fentanyl Use
Opioid-use Disorder
University of Pennsylvania60 enrolled1 locationNCT06379984