Phase 1 Opioid-use Disorder Clinical Trials

12 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 112 of 12 trials

Recruiting
Phase 1

STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancreatitis

Pancreatic SurgeryChronic PainChronic Pancreatitis+7 more
Indiana University24 enrolled5 locationsNCT05603702
Recruiting
Phase 1

OMAR Opioid Use Disorder

Healthy ControlOpioid-use Disorder
Yale University30 enrolled1 locationNCT05683184
Recruiting
Phase 1Phase 2

Clinical Trials of Multivalent Opioid Vaccine Components

Opioid-use Disorder
New York State Psychiatric Institute45 enrolled2 locationsNCT04458545
Recruiting
Phase 1

A Study to Test Whether BI 1356225 Improves Impulsive Behavior in People With Opioid Use Disorder Who Are Taking Buprenorphine

Opioid-use Disorder
Boehringer Ingelheim60 enrolled5 locationsNCT06628622
Recruiting
Phase 1Phase 2

A Bundled Intervention

Opioid-use DisorderOpioid Overdose
University of Alabama at Birmingham190 enrolled1 locationNCT06593093
Recruiting
Phase 1

Cannabis and Opioid Use Disorder

Opioid-use Disorder
University of Kentucky15 enrolled1 locationNCT05729932
Recruiting
Phase 1

Adjunctive Effects of Psilocybin and a Formulation of Buprenorphine

Opioid-use Disorder
University of Wisconsin, Madison10 enrolled1 locationNCT04161066
Recruiting
Phase 1

Right Tools, Right Time, Right Place: Telehealth for Opioid Use Disorder in Vulnerable Settings

Opioid-use Disorder
Boulder Care250 enrolled1 locationNCT07169409
Recruiting
Phase 1

Combined Guanfacine and Mindfulness Meditation as an Adjunct to Buprenorphine Maintenance in Opioid Use Disorder

MindfulnessOpioid-use DisorderGuanfacine
Rutgers, The State University of New Jersey224 enrolled1 locationNCT06642181
Recruiting
Phase 1

Exploration of Synaptotrophic Effects of Psilocybin in Opioid Use Disorder (OUD)

Opioid-use Disorder
Yale University12 enrolled1 locationNCT06160284
Recruiting
Phase 1

Study to Assess the Use of Tezampanel for Opioid Withdrawal Syndrome in Treatment-Seeking Patients With Opioid Use Disorder

Opioid-use Disorder
Proniras Corporation40 enrolled1 locationNCT06538558
Recruiting
Phase 1Phase 2

Ketamine Assisted Psychotherapy for Opioid Use Disorder

Opioid-use Disorder
University of Utah60 enrolled1 locationNCT04892251