Phase 3 Opioid-use Disorder Clinical Trials

12 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 112 of 12 trials

Recruiting
Phase 3

Buprenorphine for Individuals in Jail

Opioid-use Disorder
Friends Research Institute, Inc.240 enrolled2 locationsNCT06306443
Recruiting
Phase 3

Standard Versus High Dose ED-Initiated Buprenorphine Induction

Opioid-use Disorder
Yale University360 enrolled5 locationsNCT06494904
Recruiting
Phase 2Phase 3

Efficacy of Buprenorphine and XR-Naltrexone Combination for Relapse Prevention in Opioid Use Disorder

Opioid-use Disorder
New York State Psychiatric Institute180 enrolled2 locationsNCT05011266
Recruiting
Phase 3

Non-invasive Vagal Nerve Stimulation in Opioid Use Disorders UH3

Opioid UseOpioid-use DisorderWithdrawal Symptoms
Emory University103 enrolled6 locationsNCT05834478
Recruiting
Phase 3

Smartphones for Opiate Addiction Recovery

Opioid-use Disorder
NYU Langone Health225 enrolled2 locationsNCT05033028
Recruiting
Phase 2Phase 3

Divided or Single Exposure (DOSE) Study

Chronic PainOpioid-use DisorderMethadone
University of Maryland, Baltimore150 enrolled1 locationNCT05459402
Recruiting
Phase 3

Treating Polysubstance Use Using a Novel Digital Technology

Opioid UseOpioid-use DisorderCocaine Use Disorder+1 more
Friends Research Institute, Inc.240 enrolled5 locationsNCT05766631
Recruiting
Phase 3

High Dose Buprenorphine (BUP) Induction in the Emergency Department (ED)

Opioid-use Disorder
Rutgers, The State University of New Jersey140 enrolled1 locationNCT05589181
Recruiting
Phase 2Phase 3

Identifying Optimal Buprenorphine Dosing for Opioid Use Disorder Treatment and Prevention of Overdose

Opioid-use Disorder
Rhode Island Hospital250 enrolled1 locationNCT06316830
Recruiting
Phase 3

Transdermal Patch for BupRenorphine Induction DurinG PrEgnancy (Patch BRIDGE)

Pregnancy ComplicationsOpioid-use DisorderPregnancy Related+2 more
Washington University School of Medicine40 enrolled1 locationNCT05790252
Recruiting
Phase 2Phase 3

Evaluating Buprenorphine/Naloxone Microdosing vs. Standard Dosing in Emergency Departments

Opioid-use Disorder
University of British Columbia658 enrolled6 locationsNCT04893525
Recruiting
Phase 3

Behavioral Pharmacological Examination of a Novel Buprenorphine Induction Method Among Individuals Who Use Fentanyl

Opioid-use Disorder
Johns Hopkins University25 enrolled1 locationNCT06089707