Organ Failure Clinical Trials

20 recruitingLast updated: June 17, 2026

There are 20 actively recruiting organ failure clinical trials across 14 countries. Studies span Not Applicable, Phase 4, Phase 2. Top locations include Beijing, Beijing Municipality, China, Bern, Switzerland, Bologna, Bologna, Italy. Updated daily from ClinicalTrials.gov.


Organ Failure Trials at a Glance

20 actively recruiting trials for organ failure are listed on ClinicalTrialsFinder across 6 cities in 14 countries. The largest study group is Not Applicable with 6 trials, with the heaviest enrollment activity in Beijing, Bern, and Bologna. Lead sponsors running organ failure studies include Auckland City Hospital, China Medical University Hospital, and Assistance Publique - Hôpitaux de Paris.

Browse organ failure trials by phase

Treatments under study

About Organ Failure Clinical Trials

Looking for clinical trials for Organ Failure? There are currently 1 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Organ Failure trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Organ Failure clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 20 trials

Recruiting

ICU Background Early Awareness for Critical deterioratiON

MortalityRespiratory FailureOrgan Failure, Multiple+2 more
ETH Zurich1,962 enrolled1 locationNCT07119411
Recruiting

Heterogeneity of Critical Illness: a Cohort Study

Organ Failure, MultipleCritically Ill
University Medical Center Groningen5,000 enrolled1 locationNCT04502511
Recruiting

Effect of oXiris Hemofilter Use in Septic Shock: A Multicenter Retrospective Cohort Study

SepsisSeptic ShockMultiorgan Failure
Seoul National University Bundang Hospital360 enrolled1 locationNCT07539883
Recruiting
Not Applicable

Evaluating the Utility of RELiZORB™ for Treating Feeding Intolerance in Critically Ill Adults With Multi-Organ Failure

Exocrine Pancreatic InsufficiencyMulti Organ Failure
Inova Health Care Services32 enrolled1 locationNCT05710315
Recruiting
Phase 4

Actualities in Procedural Sedation: Remimazolam

ASA Class III/IV PatientsCOPD III/IVAge 65 and Older+1 more
Iuliu Hatieganu University of Medicine and Pharmacy200 enrolled1 locationNCT07362173
Recruiting

Impact of Metabolite Supplementation to Restore Mitochondrial Dysfunction During Septic Shock: a Preclinical Study

Septic ShockMultiple Organ Failure
University Hospital, Angers55 enrolled1 locationNCT04288635
Recruiting
Phase 2

Senolytics To slOw Progression of Sepsis (STOP-Sepsis) Trial

-Acute infectionSepsisOrgan Failure
University of Minnesota220 enrolled10 locationsNCT05758246
Recruiting
Not Applicable

Impact of Fourier Transform Infrared Spectroscopy (FTIRS) in ICUs

Organ Failure, Multiple
University Hospital, Caen900 enrolled1 locationNCT05872152
Recruiting
Not Applicable

Evaluation of the Efficiency of Intermittent Enteral Nutrition on Multi-organ Failure From Patients With Mechanical Ventilation in Intensive Care Unit

Septic ShockOrgan Failure, MultipleIntermittent Fasting
University Hospital, Rouen174 enrolled1 locationNCT06330610
Recruiting
Phase 4

Rectal Indomethacin as Early Treatment for Acute Pancreatitis (INDOMAP Trial)

ComplicationOrgan Failure, MultipleAcute Pancreatitis+1 more
Peking Union Medical College Hospital1,504 enrolled17 locationsNCT03547232
Recruiting
Not Applicable

Hemoperfusion in Critical Patients With Septic Multiorgan Dysfunction Syndrome.

SepsisHemoperfusionMultiorgan Failure
Hospital Clinic of Barcelona48 enrolled1 locationNCT05044403
Recruiting

High-flow Nasal Oxygenation for Apnoeic Oxygenation During Intubation of the Critically Ill

Respiratory FailureHypoxiaCritical Illness+1 more
Region Stockholm150 enrolled1 locationNCT05883137
Recruiting

Electronic Archive of Internal Medicine for the Treatment of Severe Organ Failure and Liver Transplantation-MITIGO

Organ Failure, MultipleLiver Transplantation
IRCCS Azienda Ospedaliero-Universitaria di Bologna10,000 enrolled1 locationNCT06781502
Recruiting

Retrospective Analysis of Chest X-ray Severity Scoring System of COVID-19 Pneumonia

COVID-19 pneumoniaSepsisPneumonia+2 more
Osijek University Hospital200 enrolled1 locationNCT05181696
Recruiting

Metabolic Reprogramming in Renal Tubular Cells in Acute Kidney Injury Following Severe Trauma

Multi-organ Failure After Severe Trauma
Assistance Publique - Hôpitaux de Paris80 enrolled2 locationsNCT06167512
Recruiting
Not Applicable

The Impact and Effect of Traditional Chinese Medicine Treatment on Organ Failure in Critically Ill Patients

Respiratory FailureOrgan Failure, MultipleIndigestion+2 more
China Medical University Hospital350 enrolled1 locationNCT06452966
Recruiting

Burden, Mortality and Supply Costs in Intensive Care Unit Patients

End of life careMortalityFrailty+4 more
University of Ulm700 enrolled1 locationNCT04094428
Recruiting
Not Applicable

Intermittent ADVOS vs. Hemodialysis in Non-intensive Care Patients With Liver Dysfunction

Liver CirrhosisMulti Organ FailureKidney Failure, Acute+1 more
University Medical Center Mainz14 enrolled1 locationNCT06129617
Recruiting

Acute Cardiac Dysfunction in Critical Illnes

Myocardial InfarctionRight Ventricular DysfunctionMulti Organ Failure+3 more
Sahlgrenska University Hospital592 enrolled1 locationNCT05860504
Recruiting

Mitochondrial function and markers of oxidative stress in patients with organ failure

Organ failure in septic shockOrgan failure in shock without sepsis
Auckland City Hospital45 enrolled1 locationACTRN12612000047897