Osteopenia Clinical Trials

24 recruitingLast updated: June 18, 2026

There are 24 actively recruiting osteopenia clinical trials across 15 countries. Studies span Not Applicable, Phase 1, Phase 2, Phase 4. Top locations include Berlin, Germany, Berlin, State of Berlin, Germany, Bispebjerg, Region Sjælland, Denmark. Updated daily from ClinicalTrials.gov.


Osteopenia Trials at a Glance

24 actively recruiting trials for osteopenia are listed on ClinicalTrialsFinder across 6 cities in 15 countries. The largest study group is Not Applicable with 11 trials, with the heaviest enrollment activity in Berlin, Berlin, and Bispebjerg. Lead sponsors running osteopenia studies include POROUS GmbH, Bettina Mittendorfer, and Benha University.

Browse osteopenia trials by phase

Treatments under study

About Osteopenia Clinical Trials

Looking for clinical trials for Osteopenia? There are currently 35 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Osteopenia trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Osteopenia clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 24 trials

Recruiting

Peripheral Mononuclear Cells to Screen, Monitor and Stratify the Population at Risk of Osteoporosis and Fractures

OsteoporosisOsteopeniaOsteoporosis Fracture
Istituto Ortopedico Rizzoli120 enrolled2 locationsNCT06551155
Recruiting

Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD)

Heart FailureSarcopeniaOsteoporosis+11 more
Bettina Mittendorfer100 enrolled1 locationNCT07083557
Recruiting
Phase 1

Veverimer to Decrease Net Acid Excretion and Bone Resorption in Adults With Osteopenia

Osteopenia
Tufts Medical Center60 enrolled1 locationNCT07473713
Recruiting
Phase 2

Resistance Training and Rapamycin to Enhance Bone Formation in Postmenopausal Women

HealthyOsteoporosis RiskOsteopenia
Odense University Hospital148 enrolled2 locationsNCT07191353
Recruiting
Not Applicable

REMS25: Study on the Use of REMS Technology in Diseases Commonly Associated With Reduced Bone Mineral Density (BMD)

NeoplasiaOsteoporosisObesity, Overweight+6 more
Meyer Children's Hospital IRCCS100 enrolled1 locationNCT07412782
Recruiting

A Study Evaluating the Performance of Using AI Software and Chest X-rays to Screen for Osteoporosis as Compared to Standard DXA Scans in Patients 50 Years and Older

Osteoporosis/Osteopenia
Promedius Inc595 enrolled3 locationsNCT07421713
Recruiting
Not Applicable

Impact of Pilates Exercises on Bone Mineral Density in Breast Cancer Survivors Receiving Hormonal Therapy

Breast CancerBreast Cancer SurvivorsAromatase Inhibitors+2 more
Benha University60 enrolled1 locationNCT07334626
Recruiting
Not Applicable

Clinical Study to Estimate Bone Mineral Density With the POROUS Ultrasound Device

HealthyOsteoporosisOsteopenia
POROUS GmbH350 enrolled2 locationsNCT07187518
Recruiting
Not Applicable

Vibration Applications After Total Knee Arthroplasty in Osteopenic Women

OsteopeniaTotal Knee Arthroplasty
Istinye University48 enrolled1 locationNCT06988033
Recruiting
Not Applicable

Profylactic Treatment for Patients in Risk Osteoporosis

Osteopenia or Osteoporosis
Meddoc60 enrolled1 locationNCT05787808
Recruiting
Phase 4

Zoledronic Acid for the Prevention of TDF-sparing ART-induced Bone Mass Density Loss in Treatment-naive HIV Positive Individuals

OsteopeniaHIV Infected Individuals
Hadassah Medical Organization110 enrolled3 locationsNCT06762730
Recruiting
Not Applicable

Clinical Study to Predict the Risk of Bone Fractures With the POROUS Ultrasound Device

HealthyOsteoporosisOsteopenia
POROUS GmbH1,600 enrolled6 locationsNCT06567054
Recruiting
Not Applicable

Effects of High-Intensity Interval Training on Bone Health in Hong Kong Older Women

Osteopenia
Hong Kong Baptist University48 enrolled1 locationNCT06888544
Recruiting
Not Applicable

A Pilot Study of Vitamin K2 (Menaquinone-7, Soloways ™) in Patients With Osteopenia/Osteoporosis Carrying a VDR Gene Variant

OsteoporosisOsteopenia
S.LAB (SOLOWAYS)40 enrolled1 locationNCT06867952
Recruiting
Not Applicable

Functional and Metabolic Effects of Fonte Fausta® Water on Bone and Muscle Health in Osteoporotic Patients

SarcopeniaOsteopenia, Osteoporosis
ANTIMO100 enrolled1 locationNCT06851676
Recruiting
Not Applicable

Effect of Manual Therapy on Low Back Pain in Osteopenic Postmenopausal Women

OsteopeniaLow Back Pain
Cairo University40 enrolled1 locationNCT06671665
Recruiting
Not Applicable

Physical Activity Guarantees Bone Density.

OsteoporosisOsteopenia
Poznan University of Physical Education300 enrolled1 locationNCT06606769
Recruiting

Skeletal Effects of Type 1 Diabetes on Low-Trauma Fracture Risk

Fractures, BoneType 1 DiabetesOsteopenia+1 more
Creighton University80 enrolled1 locationNCT05701254
Recruiting

The Impact of Hormonal Contraceptive Use and Lifestyle Factors on Fracture Risk and Bone Quality in Young Female Adults

Body CompositionPhysical ActivityOsteoporosis+8 more
Bundeswehr University Munich150 enrolled1 locationNCT06608862
Recruiting

The CHILL BONES trial: testing Tai Chi and high intensity resistance and impact training (HiRIT) as therapy for older adults with low bone mass.

Autonomic DysfunctionOsteoporosisFracture+1 more
Griffith University168 enrolled1 locationACTRN12623001209684