Ovarian Insufficiency Clinical Trials

1 recruiting

Frequently Asked Questions

Common questions about Ovarian Insufficiency clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 117 of 17 trials

Recruiting
Phase 3

Hormone Replacement Therapy in Adolescents With Premature Ovarian Insufficiency

Premature Ovarian Insufficiency
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)185 enrolled1 locationNCT06851754
Recruiting

Identifying Genome Variants in Non-Obstructive Azoospermia (NOA) or Primary Ovarian Insufficiency (POI)

AzoospermiaPrimary Ovarian InsufficiencyOligospermia
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)500 enrolled2 locationsNCT07357701
Recruiting
Not Applicable

Ventricular Repolarization in Patients With Premature Ovarian Insufficiency (QTIOP)

Premature Ovarian Insufficiency
Assistance Publique - Hôpitaux de Paris120 enrolled3 locationsNCT04167033
Recruiting

Microbiome and Premature Ovarian Insufficiency

Reproductive HealthPremature Ovarian Insufficiency
Westlake University40 enrolled2 locationsNCT07275671
Recruiting
Not Applicable

Ovarian Tissue Transplantation

Infertile Females or Females With Ovarian Insufficiency
Abramson Cancer Center at Penn Medicine10 enrolled1 locationNCT01870752
Recruiting
Phase 4

Bleeding Patterns in Sequential and Continuous Progesterone Supplementation in Adolescents With Turner Syndrome

Turner SyndromePrimary Ovarian Insufficiency (Poi)
Children's Mercy Hospital Kansas City40 enrolled1 locationNCT06834594
Recruiting
Phase 1Phase 2

Clinical Study on the Safety and Efficacy of Human Amniotic Mesenchymal Stem Cells in the Treatment of Premature Ovarian Insufficiency

Premature Ovarian Insufficiency
Yan Hongli50 enrolled1 locationNCT07115082
Recruiting
Not Applicable

Treatment of Premature Ovarian Insufficiency Using Bone Marrow Cells

Premature Ovarian Insufficiency
abdulmajeed hammadi10 enrolled1 locationNCT06302543
Recruiting

Clinical Application of Serum Anti-Müllerian Hormone (AMH) Measurements

Polycystic Ovarian SyndromeAnti-Müllerian HormonePremature Ovarian Insufficiency+1 more
Chinese University of Hong Kong300 enrolled1 locationNCT05858307
Recruiting
Not Applicable

Application of Platelet-rich Plasma (PRP) in Reproductive Medicine

Premature Ovarian InsufficiencyIntrauterine Adhesion
The Fourth Affiliated Hospital of Zhejiang University School of Medicine300 enrolled1 locationNCT06645379
Recruiting
Phase 2Phase 3

Autologous Platelet Rich Plasma Intraovarian Infusion for Poor Responders

Infertility, FemaleOvary; AnomalyReproductive Sterility+3 more
Genesis Athens Clinic100 enrolled1 locationNCT05181748
Recruiting

The Correlation Between Ovarian Function and Serum Biomarkers

Premature Ovarian Insufficiency
Shi Yun35 enrolled1 locationNCT06096766
Recruiting

Assessment of Endometrial Thickness Among Adolescent and Young Adult Patients on Estrogen Replacement Therapy Using Daily Oral Micronized Progesterone Versus the Etonogestrel Implant.

Hypogonadotropic HypogonadismPrimary Ovarian InsufficiencyHormone Replacement Therapy
University of Colorado, Denver34 enrolled1 locationNCT06357442
Recruiting
Not Applicable

Application of Autologous Adipose Stromal Vascular Fraction in the Treatment of Premature Ovarian Insufficiency

Premature Ovarian Insufficiency
Rui Yang260 enrolled1 locationNCT06481969
Recruiting

The Bone Metabolism Characteristics of Premature Ovarian Insufficiency

Premature Ovarian InsufficiencyBone Diseases, Metabolic
Shi Yun60 enrolled1 locationNCT06339489
Recruiting

Polycystic Ovary Syndrome, Mitochondrial Dysfunction, Obesity, Insulin Resistance Infertility (POMODORI) Cohort

ObesityInsulin ResistancePolycystic Ovary Syndrome+3 more
Semmelweis University150 enrolled1 locationNCT06167135
Recruiting

Investigation of Copy Number Variations and Genetic Variants in POI

Primary Ovarian Insufficiency
Ospedale Policlinico San Martino100 enrolled1 locationNCT05327283