Overload Clinical Trials

1 recruiting

About Overload Clinical Trials

Looking for clinical trials for Overload? There are currently 1 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Overload trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Overload clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 28 trials

Recruiting
Not Applicable

ReDS-guided Decongestion Strategy in Patients Hospitalized for Heart Failure

Acute Heart Failure (AHF)Heart Failure (for Example, Fluid Overload)Heart Failure Hospitalization
Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal1,014 enrolled25 locationsNCT07484009
Recruiting

Fully Automated High-Throughput Quantitative MRI of the Liver

HealthyLiver FatIron Overload
University of Wisconsin, Madison200 enrolled1 locationNCT05294471
Recruiting

Concordance and Discordance in the Assessment of Volume Status in Home Dialysis Patients: A Comparison of Modified Medical Research Council Dyspnea Scale, Physical Exam, and Point of Care Ultrasound (POCUS)

Fluid OverloadLung UltrasoundPOCUS+1 more
Indiana University90 enrolled1 locationNCT07178470
Recruiting
Not Applicable

Impact of Dietary Phosphate Excess on Exercise Capacity and Visceral Adiposity

Physical InactivityPhosphate OverloadVisceral Obesity
University of Texas Southwestern Medical Center124 enrolled1 locationNCT05147909
Recruiting

Timing and Dose of Fluid Deresuscitation in Critically Ill Patients

Fluid OverloadCritical Care, Intensive CareDeresuscitation
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)150 enrolled2 locationsNCT07275658
Recruiting
Not Applicable

Early Deresuscitation Strategy Driven by Tissue Perfusion in Renal Replacement Therapy in Patients With Acute Renal Failure

Acute Kidney InjuryFluid Overload
Hospices Civils de Lyon250 enrolled14 locationsNCT05817539
Recruiting
Not Applicable

Blood Pressure Slopes and Ultrafiltration in Hemodialysis Patients

HypertensionEnd Stage Renal DiseaseExtracellular Volume Overload+1 more
VA Office of Research and Development69 enrolled1 locationNCT04163614
Recruiting

Interview Study of Adult and Child Patients and Parents of Children With Swelling Due to Nephrotic Syndrome.

EdemaNephrotic Syndrome in ChildrenMembranous Nephropathy+10 more
University of Michigan150 enrolled1 locationNCT05505500
Recruiting
Not Applicable

Lung Ultrasound-Guided Fluid Deresuscitation in ICU Patients

Mechanical VentilationFluid OverloadDeresuscitation+1 more
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)1,000 enrolled3 locationsNCT05188092
Recruiting
Phase 4

Gator SCALES-WHF: SubCutaneous Administration of Lasix to Eliminate Symptoms of Worsening Heart Failure

Heart FailureVolume Overload
University of Florida100 enrolled1 locationNCT06979726
Recruiting

Timing of Renal Replacement Therapy in the Critically Ill Patients

Acute Kidney InjuryCritical IllnessFluid Overload+2 more
Karolinska University Hospital50,000 enrolled1 locationNCT03629977
Recruiting
Not Applicable

Ultrafiltration Versus IV Diuretics in Worsening Heart Failure

Heart FailureFluid OverloadHeart Failure (for Example, Fluid Overload)
Nuwellis, Inc.372 enrolled17 locationsNCT05318105
Recruiting

Heme and Non-heme Iron Intakes, Gut Microbiota, and Influence on Host Iron Absorption

Iron OverloadAnemia, Iron Deficiency
Cornell University120 enrolled1 locationNCT06146608
Recruiting

Fluid Administration and Fluid Accumulation in the Intensive Care Unit

Fluid OverloadFluid TherapyFluid Accumulation
Nordsjaellands Hospital1,000 enrolled21 locationsNCT06258616
Recruiting
Phase 4

Controlled Fluid Removal in Critical Ill Patients With Fluid Overload in the Intensive Care Unit.

Fluid Overload
Morten H. Bestle1,000 enrolled24 locationsNCT04180397
Recruiting
Not Applicable

Optimization of Fluid Balance Guided by Bioelectrical Impedance Analysis in Patients Undergoing Continuous Renal Replacement Therapy in Critical Care

DiureticsCongestionRRT+4 more
Centre Hospitalier Universitaire, Amiens60 enrolled1 locationNCT06799910
Recruiting
Not Applicable

ULtrafiltration-Rate Induced CArdiac Strain (ULRICA) - Study

Fluid OverloadDialysis; Complications
Umeå University40 enrolled1 locationNCT06153888
Recruiting

Comparing the Diagnostic Sensitivity and Specificity of Pleural Fluid N-Terminal Pro B-type Natriuretic Peptide (NT-proBNP) and Other Biochemical Gradient Criteria in Distinguishing Heart Failure and Non-heart Failure Related Pleural Effusions (CENTRE Study)

Heart FailureMalignant NeoplasmCirrhosis+5 more
Chinese University of Hong Kong120 enrolled1 locationNCT05797649
Recruiting
Not Applicable

Inferior Vena Cava Collapsibility Index Guide for Preoperative Fluid Therapy in Preeclampsia

Pre-EclampsiaHypotensionFluid Overload
Ain Shams University90 enrolled1 locationNCT06539026
Recruiting

Neurodegenerative Diseases Progression Markers (MARKERS-NDD)

Cognitive ImpairmentDementiaMultiple System Atrophy+15 more
Casa di Cura San Raffaele Cassino600 enrolled1 locationNCT06596746