Phase 2 Pancreatic Adenocarcinoma Clinical Trials

56 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 56 trials

Recruiting
Phase 2

APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation

Pancreatic Acinar Cell CarcinomaResectable Pancreatic CarcinomaResectable Pancreatic Adenocarcinoma+4 more
National Cancer Institute (NCI)152 enrolled453 locationsNCT04858334
Recruiting
Phase 1Phase 2

A Phase 1 Study to Evaluate Safety and Efficacy of XER-001 (Amifostine for Nasoduodenal Delivery) in Combination With Sterotactic Body Radiotherapy for Treatment in Patients With Locally Advanced Pancreatic Cancer.

Locally Advanced Pancreatic AdenocarcinomaLocally Advanced Pancreas CancerLocally Advanced Pancreatic Ductal Adenocarcinoma
Xerient Pharma36 enrolled4 locationsNCT07157033
Recruiting
Phase 2

FAPI-PET Value for the Initial Screening of Pancreatic and Biliary Cancers

CholangiocarcinomaPancreatic Adenocarcinoma
University Hospital, Bordeaux120 enrolled1 locationNCT07478523
Recruiting
Phase 2

Multicenter Trial of ESK981 in Patients With Select Solid Tumors

Pancreatic AdenocarcinomaPancreatic Neuroendocrine TumorGastrointestinal Neuroendocrine Tumor+4 more
University of Michigan Rogel Cancer Center66 enrolled3 locationsNCT05988918
Recruiting
Phase 1Phase 2

Basal-like PDAC Treated With Gemcitabine, Erlotinib, and Nab-paclitaxel

Metastatic Pancreatic CancerPancreatic AdenocarcinomaBasal Cell Neoplasm
UNC Lineberger Comprehensive Cancer Center104 enrolled1 locationNCT06483555
Recruiting
Phase 1Phase 2

Study to Assess GTAEXS617 in Participants With Advanced Solid Tumors

Head and Neck Squamous Cell Carcinoma (HNSCC)Non-small Cell Lung Cancer (NSCLC)Pancreatic Adenocarcinoma+2 more
Exscientia AI Ltd., a wholly owned subsidiary of Recursion Pharmaceuticals, Inc.230 enrolled13 locationsNCT05985655
Recruiting
Phase 2

Evaluating NALIRIFOX vs Modified Gemcitabine, Nab-Paclitaxel and Cisplatin in Patients With Locally Advanced and Metastatic Pancreatic Adenocarcinoma

Locally Advanced Pancreatic AdenocarcinomaMetastatic Pancreatic Adenocarcinoma
Medical University of South Carolina52 enrolled1 locationNCT07076212
Recruiting
Phase 2

Gemcitabine, Cisplatin and Nab-Paclitaxel as Neoadjuvant Treatment for Patients With Resectable or Borderline Resectable Pancreatic Cancer

Stage II Pancreatic Cancer AJCC v8Stage III Pancreatic Cancer AJCC v8Resectable Pancreatic Adenocarcinoma+2 more
Emory University36 enrolled1 locationNCT06423326
Recruiting
Phase 2

A Study of High Dose Radiation Therapy for Locally Advanced Pancreatic Cancer That Responded to Initial Chemotherapy Treatment

Locally Advanced Pancreatic Adenocarcinoma
University Health Network, Toronto43 enrolled2 locationsNCT06453486
Recruiting
Phase 1Phase 2

A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors

Pancreatic AdenocarcinomaGastric or Gastro-esophageal Junction (GEJ) Adenocarcinoma
Astellas Pharma Global Development, Inc.150 enrolled8 locationsNCT07488676
Recruiting
Phase 2

Stereotactic Body Radiotherapy Plus FAK and RAF/MEK Inhibition in Advanced Pancreatic Adenocarcinoma

Pancreatic CancerPancreas CancerPancreatic Adenocarcinoma+1 more
Washington University School of Medicine36 enrolled1 locationNCT07126158
Recruiting
Phase 1Phase 2

Testing the Addition of a New Anti-cancer Drug, M3814 (Peposertib), to the Usual Radiotherapy in Patients With Locally Advanced Pancreatic Cancer

Stage III Pancreatic Cancer AJCC v8Locally Advanced Pancreatic Adenocarcinoma
National Cancer Institute (NCI)92 enrolled44 locationsNCT04172532
Recruiting
Phase 2

A Study of NovoTTF-200T(P) in Combination With Gemcitabine and Nab-Paclitaxel for Resectable Pancreatic Adenocarcinoma

Pancreatic AdenocarcinomaResectable Pancreatic Cancer
Ashish Manne38 enrolled1 locationNCT05624918
Recruiting
Phase 2

Acoustic Cluster Therapy (ACT) With Chemotherapy for the Treatment of Locally Advanced Pancreatic Cancer

Locally Advanced Pancreatic Adenocarcinoma
EXACT Therapeutics AS25 enrolled10 locationsNCT06850623
Recruiting
Phase 2

Neoadjuvant Chemotherapy for Borderline Resectable and Locally Advanced Pancreatic Adenocarcinoma

Pancreas AdenocarcinomaLocally Advanced Pancreatic AdenocarcinomaBorderline Resectable Pancreatic Adenocarcinoma
Wake Forest University Health Sciences64 enrolled1 locationNCT05825066
Recruiting
Phase 1Phase 2

Prehabilitation for EOC, Fallopian Tube, Primary Peritoneal Carcinoma and Pancreatic Cancer w/ NACT

Ovarian CancerPancreatic AdenocarcinomaEpithelial Ovarian Cancer
Case Comprehensive Cancer Center22 enrolled1 locationNCT06412510
Recruiting
Phase 1Phase 2

Panitumumab-IRDye800 in Patients With Pancreatic Cancer Undergoing Surgery

Pancreatic Adenocarcinoma
George Poultsides27 enrolled1 locationNCT03384238
Recruiting
Phase 1Phase 2

Nab-Paclitaxel + Cisplatin + Gemcitabine + TTF in pt. w/ Metastatic PAC

Metastatic Pancreatic CancerPancreas CancerPancreatic Adenocarcinoma+1 more
Mayo Clinic40 enrolled1 locationNCT04605913
Recruiting
Phase 2Phase 3

Risk-adapted Adjuvant Chemotherapy Guided by the Tumour Stage for Operated Pancreatic Adenocarcinoma Following Neoadjuvant Chemotherapy With mFOLFIRINOX

Resected Pancreatic Adenocarcinoma
University Hospital, Rouen390 enrolled1 locationNCT07044453
Recruiting
Phase 1Phase 2

Neoadjuvant Triple Therapy for (Borderline) Resectable Pancreatic Cancer (PREOPANC-5)

Borderline Resectable Pancreatic AdenocarcinomaResectable Pancreatic AdenocarcinomaLocalized Pancreatic Adenocarcinoma
Amsterdam UMC, location VUmc66 enrolled4 locationsNCT06384560