PAP Clinical Trials

1 recruiting

Frequently Asked Questions

Common questions about PAP clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 108 trials

Recruiting
Phase 2

Testing of Bevacizumab, Erlotinib, and Atezolizumab in Combination for Advanced-Stage Kidney Cancer

Stage III Renal Cell Cancer AJCC v8Stage IV Renal Cell Cancer AJCC v8Renal Cell Carcinoma+3 more
National Cancer Institute (NCI)65 enrolled13 locationsNCT04981509
Recruiting
Phase 2

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

Stage IV Renal Cell Cancer AJCC v8Stage IVB Prostate Cancer AJCC v8Large Cell Neuroendocrine Carcinoma+42 more
National Cancer Institute (NCI)314 enrolled576 locationsNCT03866382
Recruiting
Not Applicable

Self-collection for HPV Testing to Improve Cervical Cancer Prevention (SHIP) Trial (LMI-001-A-S01)

Cervical CarcinomaHuman Papillomavirus Infection
National Cancer Institute (NCI)750 enrolled14 locationsNCT06498661
Recruiting

The Role of Circulating Tumour DNA in Head and Neck Cancer

Oropharyngeal Squamous Cell CarcinomaHuman Papillomavirus (HPV)
University of Edinburgh250 enrolled5 locationsNCT05539638
Recruiting

Radiofrequency Ablation for Management of Benign/Indeterminate Thyroid Nodules and Low Risk Papillary Thyroid Cancers

Radiofrequency AblationPapillary Thyroid CancerLow Risk
M.D. Anderson Cancer Center50 enrolled1 locationNCT07140757
Recruiting

Studies on Tumors of the Thyroid

Thyroid CancerPapillary Thyroid CancerFollicular Thyroid Cancer+2 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)2,500 enrolled1 locationNCT00001160
Recruiting
Not Applicable

Point of Care - Triage and Treatment for Cervical Pre-cancer

Cervical Intraepithelial NeoplasiaHuman Papillomavirus InfectionCervical Precancer
Basic Health International, Inc.5,000 enrolled1 locationNCT07461818
Recruiting
Phase 1Phase 2

Palbociclib and Sasanlimab for the Treatment of Advanced Clear Cell Renal Cell Carcinoma (ccRCC) or Papillary Renal Cell Carcinoma (pRCC)

Advanced Clear Cell Renal Carcinoma (Ccrcc)Papillary Renal Cell Carcinoma (Prcc)
National Cancer Institute (NCI)100 enrolled1 locationNCT05665361
Recruiting
Phase 2

A Study of Reduced Radiation Therapy and Standard-of-Care Chemotherapy in People With HPV-Positive Throat Cancer

Oropharyngeal CancerThroat CancerHuman Papilloma Virus+2 more
Memorial Sloan Kettering Cancer Center121 enrolled7 locationsNCT05491512
Recruiting
Phase 2

Neoadjuvant Chemotherapy and Programmed Cell Death Protein 1(PD-1) Inhibition for Head and Neck Cancer Treatment De-escalation (NeoScorch HN)

Head and Neck CancerLaryngeal CancerOral Cavity Cancer+6 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins75 enrolled1 locationNCT07209189
Recruiting

Management of Pancreatic Cystic Lesions Using Artificial Intelligence Based on EUS and Multimodal Data

Intraductal Papillary Mucinous Neoplasm of PancreasPancreatic Cystic LesionMucinous Cystadenoma of Pancreas+3 more
Huazhong University of Science and Technology500 enrolled2 locationsNCT07463872
Recruiting
Phase 1Phase 2

TheraT® Vectors (Vaccines) Combined With Chemotherapy to Treat HPV16 Head and Neck Cancers

Head and Neck CancerHPV Positive Oropharyngeal Squamous Cell CarcinomaHuman Papilloma Virus+1 more
University of Chicago98 enrolled1 locationNCT05108870
Recruiting

Evaluation of 18F-TFB PET/CT Scan in Patients With Differentiated Thyroid Cancer

Thyroid Gland Follicular CarcinomaThyroid Gland Papillary CarcinomaDifferentiated Thyroid Gland Carcinoma
Mayo Clinic24 enrolled1 locationNCT05575440
Recruiting
Phase 1Phase 2

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

Ovarian CarcinomaColorectal CarcinomaMelanoma+19 more
Children's Oncology Group147 enrolled21 locationsNCT04851119
Recruiting

Prospective Assessment of HPV Associated Anogenital Pathology in Female Patients and Female Partners of Patients With Confirmed HPV Associated Oropharyngeal Carcinoma, PAP-OP Study

Oropharyngeal Human Papillomavirus-Positive Squamous Cell Carcinoma
Mayo Clinic154 enrolled1 locationNCT06115772
Recruiting
Phase 4

A Study to Assess the Reduction of Human Papillomavirus (HPV) Viral Infectivity and Transmission in HPV-Positive Women After Vaccination With 9vHPV (RIFT-HPV)

Cervical Intraepithelial Neoplasia Grade I/ II/ III (CIN I/II/III)Human Papillomavirus (HPV) InfectionsHigh-risk HPV+1 more
Miquel Angel Pavon Ribas69 enrolled1 locationNCT05334706
Recruiting
Not Applicable

Secondary Cervical Cancer Prevention of Vulnerable Women With HPV and HIV Co-infection in India

Cervical CancerHuman Papillomavirus (HPV) InfectionHuman Immunodeficiency Virus (HIV) Infection
University of California, Irvine420 enrolled1 locationNCT07209917
Recruiting

Clinicopathologic and Ancillary Testing of Primary Clear Cell Carcinoma of the Cervix

Human Papillomavirus-Independent Cervical Adenocarcinoma, Clear Cell-Type
M.D. Anderson Cancer Center70 enrolled1 locationNCT05046080
Recruiting
Not Applicable

Self-collection for HPV Testing to Improve Cervical Cancer Prevention (SHIP) Trial (LMI-001-A-S04)

Cervical CarcinomaHuman Papillomavirus Infection
National Cancer Institute (NCI)500 enrolled18 locationsNCT07281430
Recruiting

Role of Liquid Biopsies in HPV-associated Cancer Treatment Monitoring

Cervical CancerOropharyngeal CancerCervical Dysplasia+1 more
The Institute of Molecular and Translational Medicine, Czech Republic480 enrolled1 locationNCT05774561