PCI Clinical Trials

30 recruitingLast updated: May 21, 2026

There are 30 actively recruiting pci clinical trials across 18 countries. Studies span Not Applicable, Phase 4, Phase 3. Top locations include Amsterdam, Netherlands, Groningen, Netherlands, Alicante, Alicante, Spain. Updated daily from ClinicalTrials.gov.


PCI Trials at a Glance

30 actively recruiting trials for pci are listed on ClinicalTrialsFinder across 6 cities in 18 countries. The largest study group is Not Applicable with 16 trials, with the heaviest enrollment activity in Amsterdam, Groningen, and Alicante. Lead sponsors running pci studies include Nanjing First Hospital, Nanjing Medical University, Amsterdam UMC, location VUmc, and Albert Schweitzer Ziekenhuis, Netherlands.

Browse pci trials by phase

About PCI Clinical Trials

Looking for clinical trials for PCI? There are currently 4 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new PCI trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about PCI clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 30 trials

Recruiting

OPtimal stEnt Deployment stRategy oF Contemporary sTents - Registry to Evaluate Percutaneous Coronary Intervention Using Bioresorbable Scaffolds With Thinner-strut Construction and Guidance by intracOronary Imaging to REduce Scaffold Failure

Coronary Arterial Disease (CAD)Percutaneous Coronary Intervention (PCI)
Albert Schweitzer Ziekenhuis, Netherlands117 enrolled1 locationNCT06919562
Recruiting
Not Applicable

Standby Cannulated ECMO for High-Risk Percutaneous Coronary Intervention

ECMOHigh-risk PCI
Beijing Anzhen Hospital176 enrolled1 locationNCT06274411
Recruiting
Phase 4

Monotherapy With P2Y12 Inhibitors in Patients With Atrial fIbrillation Undergoing Supraflex Stent Implantation

Atrial Fibrillation (AF)Percutaneous Coronary Intervention (PCI)Oral Anticoagulation+1 more
Insel Gruppe AG, University Hospital Bern3,010 enrolled15 locationsNCT05955365
Recruiting
Not Applicable

Surgical Versus Percutaneous Revascularization in Patients With Reduced Left Ventricular Function (STICH 3.0-NL)

Heart FailureCoronary Artery DiseaseCoronary Artery Disease (CAD)+5 more
University Medical Center Groningen358 enrolled1 locationNCT07269366
Recruiting
Not Applicable

Hybrid Percutaneous Coronary Intervention Combining a Bioresorbable Scaffold With Drug-coated Balloons Versus a Conventional Drug-eluting Stent-based Strategy in Patients With Long and Diffuse Coronary Artery Disease

Coronary Artery DiseasePercutaneous Coronary Intervention (PCI)Diffuse Coronary Artery Disease
University Hospital, Geneva150 enrolled1 locationNCT06710210
Recruiting
Not Applicable

Leave Nothing Behind Study Which Compares DCB With Bail Out BRS Versus BRS Strategy Alone

Percutaneous Coronary Intervention (PCI)Acute Coronary Syndrome (ACS)Drug-coated Balloon+1 more
Ceric Sàrl2,256 enrolled1 locationNCT07038408
Recruiting
Not Applicable

Orbital Atherectomy vs Intravascular Lithotripsy for the Treatment of Calcified Coronary Nodules (ORBIT-SHOCK).

Chronic Coronary SyndromeCoronary Arterial Disease (CAD)Percutaneous Coronary Intervention (PCI)+6 more
Spanish Society of Cardiology50 enrolled6 locationsNCT06736665
Recruiting
Not Applicable

ELEVATE High-Risk PCI Pivotal Study

High-Risk Percutaneous Coronary Intervention (High-risk PCI)
Magenta Medical Ltd.290 enrolled29 locationsNCT07001332
Recruiting

Artificial Intelligence Based Timing, Infarct Size and Outcomes in Acute Coronary Occlusion Myocardial Infarction

Coronary Arterial Disease (CAD)Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI)
Azienda Ospedaliera di Bolzano1,500 enrolled1 locationNCT06910436
Recruiting
Not Applicable

Super High-pressure Balloon Versus Intravascular Lithotripsy to Prepare Severely Calcified Coronary Lesions

Coronary Arterial Disease (CAD)PCICalcified Coronary Lesions
Nanjing First Hospital, Nanjing Medical University78 enrolled3 locationsNCT07093788
Recruiting
Phase 4

Prasugrel Monotherapy Reduced Dose in Acute and Chronic Coronary Syndrome Patients After Percutaneous Coronary Intervention (PROMOTE)

Coronary Arterial Disease (CAD)Percutaneous Coronary Intervention (PCI)
J.P.S Henriques300 enrolled1 locationNCT06916520
Recruiting
Not Applicable

Aerobic Exercise-induced Effect on Endothelial Function in Patients With Ischaemic Heart Disease

Cardiorespiratory FitnessAcute Myocardial InfarctionAngina, Stable+3 more
Instituto de Investigación Sanitaria y Biomédica de Alicante132 enrolled2 locationsNCT06788275
Recruiting

Drug-Coated Balloon Primary PCI in ST-Segment Elevation Myocardial Infarction

Myocardial Infarction (MI)STEMIST Elevation Myocardial Infarction+2 more
Medical University of Vienna300 enrolled1 locationNCT07436429
Recruiting
Not Applicable

Use of Mechanical Left ventricuLar Unloading in Complex Higher-risk Indicated Procedures

High-risk PCICoronary Artery Disease Risk High
Amsterdam UMC, location VUmc98 enrolled8 locationsNCT07380217
Recruiting
Not Applicable

Impact of Pre-Hospital Heparin Loading in STEMI Patients for Primary PCI: The HELP-PCI 2 Trial

ST-elevation Myocardial Infarction (STEMI)Primary PCI
Chen Jing6,294 enrolled1 locationNCT07361783
Recruiting

The 3D Stent Study

Coronary Artery DiseasePercutaneous Coronary Intervention (PCI)
CoreAalst BV200 enrolled4 locationsNCT06898021
Recruiting
Not Applicable

Optimal Strategy to Correct Stent underexpAnsion in Resistant Lesions

Coronary angioplastyCoronary Artery DiseaseCoronary Artery Disease (CAD)+10 more
University Hospital, Clermont-Ferrand80 enrolled2 locationsNCT07316504
Recruiting

Intravascular Imaging-Guided Versus Angiography- Guided PCI in Patients With DES-ISR

In-stent RestenosisPCIIntravascular Imaging Device
Nanjing First Hospital, Nanjing Medical University1,500 enrolled1 locationNCT07297641
Recruiting
Phase 4

Effect of Empagliflozin on Inflammation

InflamationCAD - Coronary Artery DiseasePCI+1 more
Hotel Dieu de France Hospital100 enrolled1 locationNCT07292909
Recruiting
Not Applicable

"Smart Family Doctor" Assisted Comprehensive Management of Secondary Prevention Among Post Coronary Artery Bypass Graft Patients or Post Percutaneous Coronary Intervention Patients

Diabetes MellitusHypertensionHyperlipidemia+2 more
China National Center for Cardiovascular Diseases536 enrolled1 locationNCT06615609