Peritoneal Carcinomatosis Clinical Trials

29 recruiting

Peritoneal Carcinomatosis Trials at a Glance

29 actively recruiting trials for peritoneal carcinomatosis are listed on ClinicalTrialsFinder across 6 cities in 15 countries. The largest study group is Phase 2 with 10 trials, with the heaviest enrollment activity in Orange, Pittsburgh, and Lexington. Lead sponsors running peritoneal carcinomatosis studies include Hospices Civils de Lyon, University of California, Irvine, and Columbia University.

Browse peritoneal carcinomatosis trials by phase

Treatments under study

About Peritoneal Carcinomatosis Clinical Trials

Looking for clinical trials for Peritoneal Carcinomatosis? There are currently 29 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Peritoneal Carcinomatosis trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Peritoneal Carcinomatosis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 29 trials

Recruiting
Phase 1

Individual Response to Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Treatment of Peritoneal Carcinomatosis From Peritoneal Mesothelioma or Atypical Mesothelial Proliferation or From Ovarian, Colorectal, or Appendiceal Histologies

Ovarian CancerPeritoneal CarcinomatosisGastrointestinal Cancer+3 more
National Cancer Institute (NCI)60 enrolled1 locationNCT04847063
Recruiting
Not Applicable

Enhanced Recovery After Surgery (ERAS) in Patients With Peritoneal Carcinomatosis Undergoing Cytoreductive Surgery With or Without Hyperthermic Intraperitoneal Chemotherapy (HIPEC)

Peritoneal Carcinomatosis
Fondazione del Piemonte per l'Oncologia300 enrolled2 locationsNCT07493876
Recruiting
Phase 2

Flat Dose vs. Weight-based IP Chemotherapy for CRS/HIPEC

Peritoneal Carcinomatosis
Prakash Pandalai100 enrolled2 locationsNCT04779554
Recruiting
Phase 2Phase 3

Testing the Addition of Paclitaxel Administered Into the Abdominal Cavity Combined With Chemotherapy for Patients With Gastric Cancer Spread to the Abdominal Cavity

Gastroesophageal Junction AdenocarcinomaPeritoneal CarcinomatosisGastric Adenocarcinoma
ECOG-ACRIN Cancer Research Group148 enrolled10 locationsNCT07001748
Recruiting
Phase 2

A Study of Radspherin® in Patients With Primary Advanced Epithelial Cancer, With Peritoneal Metastasis That Are Homologous Recombination Proficient Scheduled to Undergo Neoadjuvant Chemotherapy and Interval Debulking Surgery

Ovarian CancerPeritoneal Carcinomatosis
Oncoinvent Solutions AS114 enrolled10 locationsNCT06504147
Recruiting
Phase 2

Heated Versus Aerosol-based Laparoscopic Chemotherapy for Cancer That Has Spread to the Peritoneum (Abdominal Lining)

Peritoneal CarcinomatosisAbdominal CancerPeritoneal (Metastatic) Cancer+1 more
Patrick Wagner, MD, FACS200 enrolled1 locationNCT07282834
Recruiting
Early Phase 1

PhI Pilot Study Pafolacianine Inject for Intraoperative Imaging on Outcomes of GI Cancer Peritoneal Carcinomatosis

Peritoneal CarcinomatosisGastrointestinal Cancer
University of California, Irvine10 enrolled1 locationNCT06511037
Recruiting
Not Applicable

Blood Clearance Kinetics of the Nucleosome and CTCF in Peritoneal Metastasis Colorectal Cancer.

Peritoneal CarcinomatosisPeritoneal Metastases From Colorectal Cancer
Hospices Civils de Lyon58 enrolled1 locationNCT06929013
Recruiting
Phase 1

A Study of Mesothelin-Targeted CAR T-Cell Therapy in People With Esophagogastric Cancer

Breast NeoplasmsEsophageal AdenocarcinomaMesothelin Positive+5 more
Memorial Sloan Kettering Cancer Center18 enrolled7 locationsNCT06623396
Recruiting
Not Applicable

Impact of Cardiac Coherence on Anxiety in Patients Operated on for a Peritoneal Carcinosis

Peritoneal CarcinomatosisPseudomyxoma PeritoneiMesothelioma Peritoneum
Institut du Cancer de Montpellier - Val d'Aurelle60 enrolled1 locationNCT04024917
Recruiting
Phase 1

PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric Cancer

Malignant Uterine NeoplasmPeritoneal CarcinomatosisClinical Stage IV Gastric Cancer AJCC v8+24 more
City of Hope Medical Center49 enrolled3 locationsNCT04329494
Recruiting
Phase 2

Phase II Study of the Effects of Laparoscopic Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Patients With Advanced Gastric Cancer

Gastric CancerPeritoneal Carcinomatosis
University of Chicago21 enrolled1 locationNCT04107077
Recruiting
Phase 2

Surgery and Heated Intraperitoneal Chemotherapy for Adrenocortical Carcinoma

Peritoneal CarcinomatosisAdrenocortical Carcinoma
Columbia University30 enrolled1 locationNCT03127774
Recruiting
Not Applicable

Patient Derived Vascularized MicroTumor Model of Gastrointestinal Peritoneal Carcinomatosis

Peritoneal CarcinomatosisGastrointestinal Peritoneal Carcinomatosis
University of California, Irvine20 enrolled1 locationNCT05844865
Recruiting
Phase 1

Intraperitoneal Aerosolized Nanoliposomal Irinotecan (Nal-IRI) in Peritoneal Carcinomatosis From Gastrointestinal Cancer

Peritoneal CarcinomatosisPeritoneal Metastases
University Hospital, Ghent45 enrolled1 locationNCT05277766
Recruiting

Response Prediction of Hyperthermic Intraperitoneal Chemotherapy in Gastro- Intestinal Cancer

Gastric CancerColon CancerPeritoneal Carcinomatosis
Technische Universität Dresden48 enrolled2 locationsNCT05652348
Recruiting
Not Applicable

Ga68-FAPI-46 PET/CT for Preoperative Assessment of Peritoneal Carcinomatosis

CancerPeritoneal Carcinomatosis
Jules Bordet Institute80 enrolled1 locationNCT06061874
Recruiting
Phase 4

Clinical Trial on HIPEC With Mitomycin C in Colon Cancer Peritoneal Metastases (GECOP-MMC)

Colon CancerPeritoneal Carcinomatosis
Hospital Universitario de Fuenlabrada216 enrolled31 locationsNCT05250648
Recruiting
Phase 1

Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) Associated With Systemic Chemotherapy in Women With Advanced Ovarian Cancer

Peritoneal CarcinomatosisMetastatic Ovarian CarcinomaMetastatic Malignant Neoplasm in the Peritoneum+4 more
Hospices Civils de Lyon15 enrolled6 locationsNCT04811703
Recruiting
Phase 2

Technical Feasibility of Modified Early Post-Operative Intraperitoneal Chemotherapy (mEPIC)

Peritoneal CarcinomatosisColorectal Cancer MetastaticAppendiceal Neoplasms
Ciusss de L'Est de l'Île de Montréal25 enrolled1 locationNCT05913674