Phase 1 Pleural Mesothelioma Clinical Trials
10 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–10 of 10 trials
Recruiting
Phase 1
A Study of BMS-986504 With Standard-of-Care Therapy for People With Solid Tumor Cancer
Urothelial CarcinomaDiffuse Pleural MesotheliomaGastroesophageal Carcinoma
Memorial Sloan Kettering Cancer Center60 enrolled7 locationsNCT07532902
Recruiting
Phase 1Phase 2
A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy
MelanomaAdvanced Solid TumorMetastasis+5 more
7 Hills Pharma, LLC126 enrolled5 locationsNCT06362369
Recruiting
Phase 1
A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors
Gastric AdenocarcinomaBladder CancerMesothelioma+7 more
IDEAYA Biosciences260 enrolled10 locationsNCT07277413
Recruiting
Phase 1Phase 2
Dual-Target MSLN/FAP CAR-NK Cells for Pleural and Peritoneal Mesothelioma
Malignant Pleural Mesotheliomas
Beijing Biotech36 enrolled1 locationNCT07510815
Recruiting
Phase 1
A Study of NX-1607 in Adults With Advanced Malignancies
Gastric CancerNon-small Cell Lung Cancer (NSCLC)Head and Neck Squamous Cell Carcinoma+5 more
Nurix Therapeutics, Inc.345 enrolled17 locationsNCT05107674
Recruiting
Phase 1
CT-95 in Advanced Cancers Associated With Mesothelin Expression
Mesothelin-Expressing TumorsEpithelial Ovarian CancerLung Adenocarcinoma Metastatic+7 more
Context Therapeutics Inc.70 enrolled8 locationsNCT06756035
Recruiting
Phase 1
A Study of MT027 in Patients with Pleural Malignant Tumors
Malignant Pleural EffusionAdvanced Malignant Solid TumorPleural Metastases+3 more
Suzhou Maximum Bio-tech Co., Ltd.18 enrolled1 locationNCT06726564
Recruiting
Phase 1Phase 2
Integration of the PD-L1 Inhibitor Atezolizumab and WT1/DC Vaccination Into Platinum/Pemetrexed-based First-line Treatment for Epithelioid Malignant Pleural Mesothelioma
Malignant Pleural Mesothelioma
University Hospital, Antwerp15 enrolled3 locationsNCT05765084
Recruiting
Phase 1
The first testing of TargomiRs in the human setting: dose-finding studies in patients with recurrent malignant pleural mesothelioma and non-small cell lung cancer
Malignant Pleural Mesothelioma
Asbestos Disease Research Institute30 enrolled3 locationsACTRN12614001248651
Completed
Phase 1
CD-40 activating antibody (CP-870,893) in combination with cisplatin and pemetrexed in unresectable malignant mesothelioma: a phase Ib study
unresectable malignant pleural mesothelioma
Sir Charles Gairdner Hospital15 enrolled1 locationACTRN12609000294257