Phase 2 Pleural Mesothelioma Clinical Trials

11 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 111 of 11 trials

Recruiting
Phase 1Phase 2

A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy

MelanomaAdvanced Solid TumorMetastasis+5 more
7 Hills Pharma, LLC126 enrolled5 locationsNCT06362369
Recruiting
Phase 1Phase 2

Dual-Target MSLN/FAP CAR-NK Cells for Pleural and Peritoneal Mesothelioma

Malignant Pleural Mesotheliomas
Beijing Biotech36 enrolled1 locationNCT07510815
Recruiting
Phase 2

Study of Volrustomig as Monotherapy or in Combination With Anti- Cancer Agents in Participants With Advanced/Metastatic Solid Tumors

Sub-study 1 Cervical Cancer (Volrustomig Monotherapy)Sub-study 2 Head and Neck Squamous Cell Carcinoma (Volrustomig Monotherapy)Sub-study 3 Head and Neck Squamous Cell Carcinoma (Volrustomig in Combination With Chemotherapy)+2 more
AstraZeneca257 enrolled59 locationsNCT06535607
Recruiting
Phase 2

Evaluating Ivonescimab as a Potential Treatment for Pleural Mesothelioma Patients Whose Cancer Has Returned After Previous Immunotherapy and Chemotherapy

Pleural Mesotheliomas
Intergroupe Francophone de Cancerologie Thoracique38 enrolled20 locationsNCT06840834
Recruiting
Phase 2

The IMmunotherapy Pleural 5-ALA PDT

Malignant Pleural MesotheliomaMesotheliomas Pleural
University Hospital, Lille20 enrolled1 locationNCT04400539
Recruiting
Phase 2

The Diagnostic Accuracy and Clinical Value of FAPI PET in Pleural Mesothelioma

CancerPleural MesotheliomaPleural Diseases+2 more
Aalborg University Hospital70 enrolled1 locationNCT06790082
Recruiting
Phase 2

Study of Pembrolizumab Plus Chemotherapy With Lenvatinib for Malignant Pleural Mesothelioma

Malignant Pleural Mesothelioma
Hyogo Medical University25 enrolled1 locationNCT06318286
Recruiting
Phase 2

Multicenter Single-Arm Study of Ivonescimab (AK112) Combined with Chemotherapy in Pretreated Pleural Mesothelioma

Pretreated Pleural Mesothelioma
The First Hospital of Jilin University25 enrolled1 locationNCT06875076
Recruiting
Phase 1Phase 2

Integration of the PD-L1 Inhibitor Atezolizumab and WT1/DC Vaccination Into Platinum/Pemetrexed-based First-line Treatment for Epithelioid Malignant Pleural Mesothelioma

Malignant Pleural Mesothelioma
University Hospital, Antwerp15 enrolled3 locationsNCT05765084
Recruiting
Phase 2

Study of Cadonilimab Combined With Bevacizumab and Standard Chemotherapy as First Line Therapy in Unresectable Pleural Mesothelioma

Pleural Mesothelioma
Sun Yat-sen University38 enrolled1 locationNCT05930665
Completed
Phase 2

B2P2M2: Phase II trial of BNC105P as 2nd line chemotherapy for advanced malignant pleural mesothelioma

Advanced malignant pleural mesothelioma
University of Sydney60 enrolled1 locationACTRN12610000093088