Post-traumatic Osteoarthritis Clinical Trials

8 recruiting

Post-traumatic Osteoarthritis Trials at a Glance

11 actively recruiting trials for post-traumatic osteoarthritis are listed on ClinicalTrialsFinder across 6 cities in 5 countries. The largest study group is Not Applicable with 5 trials, with the heaviest enrollment activity in New York, Chapel Hill, and Lexington. Lead sponsors running post-traumatic osteoarthritis studies include Hospital for Special Surgery, New York, University of North Carolina, Chapel Hill, and DT MedTech, LLC.

Browse post-traumatic osteoarthritis trials by phase

Treatments under study

About Post-traumatic Osteoarthritis Clinical Trials

Looking for clinical trials for Post-traumatic Osteoarthritis? There are currently 8 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Post-traumatic Osteoarthritis trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Post-traumatic Osteoarthritis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 111 of 11 trials

Recruiting
Phase 3

PRP in ACLR to Prevent PTOA

Post-traumatic OsteoarthritisAnterior Cruciate Ligament InjuriesPRP
Hospital for Special Surgery, New York56 enrolled1 locationNCT05412381
Recruiting

Exactech Shoulder Post Market Clinical Follow-up Study

Rheumatoid ArthritisInfectionsAnkylosing Spondylitis+6 more
Exactech20,000 enrolled38 locationsNCT05603728
Recruiting
Phase 4

Concentrated Bone Marrow Aspirate in Revision ACL Reconstruction

Anterior Cruciate Ligament InjuriesACL InjuryPost-Traumatic Osteoarthritis of Knee+1 more
Hospital for Special Surgery, New York40 enrolled2 locationsNCT06311513
Recruiting
Not Applicable

Gait Rehabilitation to Treat FastOA

Knee OsteoarthritisOsteo Arthritis KneePost-traumatic Osteoarthritis+1 more
University of North Carolina, Chapel Hill70 enrolled1 locationNCT05848622
Recruiting
Not Applicable

Vibration and Post-traumatic Osteoarthritis Risk Following ACL Injury

Osteoarthritis, KneePost-traumatic OsteoarthritisQuadriceps Muscle Atrophy+1 more
University of North Carolina, Chapel Hill114 enrolled2 locationsNCT04875052
Recruiting
Early Phase 1

MOntelukast as a Potential CHondroprotective Treatment Following Anterior Cruciate Ligament Reconstruction (MOCHA Trial)

Post-traumatic OsteoarthritisACL InjuryMeniscus Tear
Austin V Stone30 enrolled1 locationNCT04572256
Recruiting
Phase 2

Preventing Injured Knees From osteoArthritis: Severity Outcomes

Osteoarthritis, KneePost-traumatic OsteoarthritisACL Tear
Brigham and Women's Hospital512 enrolled9 locationsNCT06096259
Recruiting

Safety and Performance Assessment of the SYMBOL Range of Medical Devices in Patients Underlying Total Hip Arthroplasty

Avascular Necrosis of the Femoral HeadPost-traumatic OsteoarthritisHip Arthritis+3 more
Dedienne Sante S.A.S.747 enrolled9 locationsNCT05227924
Recruiting
Not Applicable

Post Approval Study2: Hintermann Series H3 Total Ankle Replacement System

Osteoarthritis AnklePost-Traumatic Osteoarthritis of AnkleOsteoarthritis of Ankle Secondary to Inflammatory Arthritis (Disorder)
DT MedTech, LLC232 enrolled10 locationsNCT04770870
Recruiting
Not Applicable

Does Joint Lavage Reduce Intraarticular Inflammation in High-energy Tibial Pilon Fractures?

Tibial FracturesPost-Traumatic Osteoarthritis of AnklePost-traumatic; Arthrosis
United States Naval Medical Center, San Diego40 enrolled1 locationNCT05652881
Recruiting
Not Applicable

An Imaging Framework for Clinically Testing New Treatments to Prevent Post-traumatic OA

Ankle FracturesTraumaOrthopedic Disorder+1 more
J L Marsh20 enrolled1 locationNCT03809520