Phase 4 Postoperative Pain Clinical Trials

36 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 36 trials

Recruiting
Phase 4

Opioid Free Anesthesia-Analgesia Strategy and Surgical Stress in Elective Open Abdominal Aortic Aneurysm Repair

Opioid UsePostoperative PainAnesthesia+5 more
University of Crete40 enrolled1 locationNCT04894864
Recruiting
Phase 4

Comparison of Intraperitoneal Bupivacaine and Saline Irrigation for Pain Relief After Laparoscopic Cholecystectomy

Postoperative Pain
Wah Medical college , POF hospital106 enrolled1 locationNCT07650760
Recruiting
Phase 4

Intranasal Dexmedetomidine-esketamine Administration and Postoperative Pain in Pediatric Patients

Postoperative PainEsketamineDexmedetomidine+3 more
Peking University First Hospital160 enrolled1 locationNCT07479602
Recruiting
Phase 4

Efficacy of Preventive Ketamine on Postoperative Pain

Postoperative Pain
Ain Shams University90 enrolled1 locationNCT04908579
Recruiting
Phase 4

Efficacy and Safety of Anrikefon for Postoperative Analgesia in Ophthalmic Surgery

Opioid analgesiaPostoperative Pain ManagementOphthalmic Surgery
Zhongshan Ophthalmic Center, Sun Yat-sen University204 enrolled3 locationsNCT07269106
Recruiting
Phase 4

Suprainguinal Fascia Iliaca Block With vs Without Dexmedetomidine

Postoperative Pain Management
Rhode Island Hospital120 enrolled1 locationNCT07316166
Recruiting
Phase 4

Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients

Opioid UsePostoperative PainDepression+2 more
Texas Tech University Health Sciences Center90 enrolled2 locationsNCT06903819
Recruiting
Phase 4

Effect of Intraoperative Morphine on Postoperative Pain After CABG

Postoperative PainPain After SurgeryCardiac Surgery Patient
Istanbul University - Cerrahpasa60 enrolled1 locationNCT07472959
Recruiting
Phase 4

COMFORT Trial: Complex Obstetric Management With Focused Regional Transversus Abdominis Plane Block

cesarean deliveryPostoperative pain controlperioperative pain management+1 more
University of Tennessee120 enrolled1 locationNCT06925152
Recruiting
Phase 4

Determination of the Effective Dose of a Single Intravenous Dose of Tegileridine Fumarate for Postoperative Analgesia After Orthopedic Surgery: A Up-and-Down Sequential Allocation Study

Postoperative Pain
Second Affiliated Hospital, School of Medicine, Zhejiang University180 enrolled1 locationNCT07353996
Recruiting
Phase 4

Efficacy and Safety of Intrathecal Morphine for Postoperative Pain Management Following Planned Caesarean Section

Postoperative PainCaesarean Section
Anne Juul Wikkelsø1,312 enrolled8 locationsNCT06797973
Recruiting
Phase 4

Meloxicam in Mohs Micrographic Surgery

Skin CancerPostoperative Pain, Acute
University of Oklahoma300 enrolled1 locationNCT07200544
Recruiting
Phase 4

Nalbuphine Timing Effects on Hemodynamics and Analgesia in Elderly Patients

Postoperative Pain, AcuteHemodynamicsTotal Knee Arthroplasty (TKA)
Qianfoshan Hospital162 enrolled1 locationNCT07271849
Recruiting
Phase 4

Effect of Lidocaine-Dexmedetomidine on Pain, Inflammation, and Oxidative Stress After Bariatric Surgery.

Postoperative PainPostoperative Adjuvant TreatmentPostoperative Pain Management+4 more
Instituto Mexicano del Seguro Social104 enrolled2 locationsNCT07073846
Recruiting
Phase 4

Paracervical Injection and Opioid Use After Vaginal Hysterectomy for Prolapse

Opioid UsePostoperative PainVaginal Hysterectomy+2 more
University of North Carolina, Chapel Hill56 enrolled1 locationNCT07213635
Not Yet Recruiting
Phase 4

Comparison of oral oxycodone versus sublingual buprenorphine for pain control after pelvic exenteration

Postoperative pain and function
University of Sydney30 enrolled3 locationsACTRN12625000901404
Recruiting
Phase 4

Magnesium and Cramping

Postoperative Pain ManagementHysteroscopyUterine Cramps
Corewell Health East150 enrolled1 locationNCT06745388
Recruiting
Phase 4

QL Block in Laparoscopic Myomectomy

Postoperative PainFibroid Uterus
Joseph Findley MD80 enrolled1 locationNCT05979493
Recruiting
Phase 4

Efficacy and Safety of Liposomal Bupivacaine Injection for Paravertebral Nerve Block in the Treatment of Acute and Chronic Pain After Thoracoscopic Pneumonectomy: A Multicenter, Randomized, Double-blind, Controlled Clinical Trial

Postoperative PainChronic PainAcute Pain
The Second Affiliated Hospital of Chongqing Medical University284 enrolled1 locationNCT06569953
Recruiting
Phase 4

Comparison of Dexmedetomidine + Ketamine for Postoperative Pain in C-Section

Postoperative PainCesarean Section Pain
Fatima Memorial Hospital90 enrolled1 locationNCT07022821