Posttraumatic Stress Clinical Trials

2 recruiting

Posttraumatic Stress Trials at a Glance

88 actively recruiting trials for posttraumatic stress are listed on ClinicalTrialsFinder across 6 cities in 14 countries. The largest study group is Not Applicable with 57 trials, with the heaviest enrollment activity in Seattle, Stockholm, and Austin. Lead sponsors running posttraumatic stress studies include VA Office of Research and Development, Karolinska Institutet, and Medical University of South Carolina.

Browse posttraumatic stress trials by phase

Treatments under study

About Posttraumatic Stress Clinical Trials

Looking for clinical trials for Posttraumatic Stress? There are currently 2 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Posttraumatic Stress trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Posttraumatic Stress clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 88 trials

Recruiting
Not Applicable

Internet-Delivered Cognitive Behaviour Therapy for PTSD Among Public Safety Personnel

DepressionAnxietyPosttraumatic Stress
University of Regina300 enrolled1 locationNCT04335487
Recruiting
Phase 2

Ketamine, SGB and Combination Treatment for TBI-associated Headache or PTSD

Posttraumatic Stress DisorderPosttraumatic Headache
Northwestern University175 enrolled3 locationsNCT06608277
Recruiting
Phase 2

Integration of Cognitive Processing Therapy and Relapse Prevention for Alcohol Use Disorder and PTSD

Alcohol Use DisorderPosttraumatic Stress Disorder
Texas A&M University200 enrolled2 locationsNCT05959434
Recruiting
Not Applicable

Improving Cognitive Rehabilitation Outcomes

Mild Traumatic Brain InjuryPosttraumatic Stress Disorder
VA Office of Research and Development144 enrolled2 locationsNCT07055633
Recruiting
Not Applicable

Multicenter iTBS Neuromodulation for PTSD Treatment

Posttraumatic Stress Disorder
Second Affiliated Hospital, School of Medicine, Zhejiang University140 enrolled5 locationsNCT06434766
Recruiting
Not Applicable

Brief Behavioral Treatment for Insomnia in Veterans With Posttraumatic Stress Disorder

Insomnia DisorderPosttraumatic Stress Disorder
VA Office of Research and Development200 enrolled1 locationNCT05780177
Recruiting
Not Applicable

Insomnia Treatment and Cardiometabolic Health in Older Adults With Posttraumatic Stress Disorder

InsomniaCardiovascular DiseasesMetabolic Disease+1 more
University of California, Los Angeles167 enrolled1 locationNCT05516277
Recruiting
Not Applicable

Advancing Couple and Family Alcohol Treatment Through Patient-Oriented Research and Mentorship

Alcohol Use DisorderPosttraumatic Stress DisorderCouples
Medical University of South Carolina140 enrolled1 locationNCT05786157
Recruiting
Not Applicable

Mindfulness-based Stress Reduction for PTSD in Road Traffic Accident Victims: A Randomized Controlled Trial

Posttraumatic Stress Disorder (PTSD)
Universiti Sains Malaysia110 enrolled1 locationNCT07521020
Recruiting
Phase 3

Repurposing Low-Dose Clonidine for PTSD in Veterans

SleepPTSDPosttraumatic Stress Disorder
Wake Forest University Health Sciences32 enrolled1 locationNCT04877093
Recruiting
Not Applicable

Biomolecular Characteristics of Reminder-Focused Positive-Psychiatry

Posttraumatic Stress Disorder
University of California, Los Angeles60 enrolled1 locationNCT04529031
Recruiting
Not Applicable

Transdiagnostic Metacognitive Therapy Compared to Disorder-Specific Cognitive-Behavioral Therapy for Anxiety Disorders

Posttraumatic Stress Disorder (PTSD)Generalized Anxiety Disorder (GAD)Social Anxiety Disorder (SAD)
Karolinska Institutet86 enrolled1 locationNCT06937892
Recruiting
Not Applicable

Exploring Efficacy of Multi-Mode Cognitive Processing Therapy (CPT) for PTSD

Posttraumatic Stress Disorder
Far Eastern Memorial Hospital60 enrolled2 locationsNCT07105345
Recruiting
Not Applicable

Family Involvement in Treatment for PTSD (FIT-PTSD): A Brief, Feasible Method for Enhancing Outcomes, Retention, and Engagement

Posttraumatic Stress Disorder
VA Office of Research and Development200 enrolled3 locationsNCT05267665
Recruiting
Not Applicable

CIH Stepped Care for Co-occurring Chronic Pain and PTSD

Chronic PainPosttraumatic Stress Disorder
University of Washington60 enrolled1 locationNCT06219408
Recruiting
Not Applicable

Augmenting Massed Cognitive Processing Therapy (CPT) to Prevent Suicide Risk Among Patients With PTSD

Suicidal IdeationPosttraumatic Stress Disorder (PTSD)Suicide Attempt
Ohio State University190 enrolled1 locationNCT07238192
Recruiting
Not Applicable

Written Exposure Therapy for Veterans With SUD and PTSD

Substance Use DisordersPosttraumatic Stress Disorder
VA Office of Research and Development170 enrolled1 locationNCT05327504
Recruiting
Not Applicable

Efficacy of an EMDR App for PTSD and SUD

Substance Use DisordersPosttraumatic Stress Disorder (PTSD)
Centre for Addiction and Mental Health24 enrolled1 locationNCT07146633
Recruiting
Not Applicable

Trauma BPE Prolonged Exposure Therapy for Injured Individuals Admitted to a Level I Trauma Center

PTSDPosttraumatic Stress DisorderTraumatic Injury
Baylor Research Institute300 enrolled3 locationsNCT06210711
Recruiting
Not Applicable

Enhancing Psychotherapy for Veterans and Service Members With PTSD and Anxiety

Anxiety DisordersPosttraumatic Stress Disorder
Baylor College of Medicine306 enrolled1 locationNCT05843695