Prostatectomy Clinical Trials

49 recruitingLast updated: June 18, 2026

There are 49 actively recruiting prostatectomy clinical trials across 21 countries. Studies span Not Applicable, Phase 3, Phase 2, Phase 1, Phase 4. Top locations include Houston, Texas, United States, New York, New York, United States, Chicago, Illinois, United States. Updated daily from ClinicalTrials.gov.


Prostatectomy Trials at a Glance

49 actively recruiting trials for prostatectomy are listed on ClinicalTrialsFinder across 6 cities in 21 countries. The largest study group is Not Applicable with 24 trials, with the heaviest enrollment activity in Houston, New York, and Chicago. Lead sponsors running prostatectomy studies include M.D. Anderson Cancer Center, Bartın Unıversity, and Axonics, Inc..

Browse prostatectomy trials by phase

Treatments under study

About Prostatectomy Clinical Trials

Looking for clinical trials for Prostatectomy? There are currently 6 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Prostatectomy trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Prostatectomy clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 49 trials

Recruiting
Phase 3

Radiotherapy After Prostatectomy for Node Positive Prostate Cancer

Androgen Deprivation TherapyProstate Cancer (Post Prostatectomy)Prostate Cancer Non-Metastatic+2 more
Sun Yat-sen University372 enrolled13 locationsNCT07477626
Recruiting
Not Applicable

Sacral Neuromodulation for Male Overactive Bladder (MOAB)

Prostate CancerProstatectomyBenign Prostatic Hyperplasia+3 more
Axonics, Inc.150 enrolled20 locationsNCT06511141
Recruiting
Phase 3

Pivotal Study of Voro Urologic Scaffold

Radical ProstatectomyStress Urinary Incontinence (SUI)
Levee Medical, Inc.266 enrolled19 locationsNCT06873581
Recruiting
Not Applicable

Effects of Rectal Indomethacin Suppository on Postoperative CRBD in Patients Undergoing LRP

Prostate Cancer (Post Prostatectomy)Perioperative AnestheticCatheter-related Bladder Discomfort (CRBD)
Zhejiang University130 enrolled1 locationNCT07607990
Recruiting
Phase 3

Robotic Opioid-free Prostatectomy Enhanced Strategy (ROPES)

Prostate CancerOpioid Consumption, PostoperativeMultimodal Analgesia+2 more
Brigham and Women's Hospital300 enrolled2 locationsNCT07427043
Recruiting
Phase 3

PROSTATE-IQ: Parallel RandOmized STudy of Personalized Apalutamide Treatment and Evaluation to Improve Quality of Life in Post-Operative Radiation With Androgen Axis Suppression. A Phase III Multi-center Study for Men With Detectable PSA After Prostatectomy for Prostate Cancer.

Prostate CancerAndrogen Axis SuppressionProstatectomy
M.D. Anderson Cancer Center120 enrolled5 locationsNCT06274047
Recruiting

EVERiST: Impact of Image Detected Accessory Pudendal Artery on Erection Recovery After Nerve Sparing Prostatectomy

Radical ProstatectomyErectile Dysfunction Following Radical ProstatectomyErectile Dysfunction Due to Arterial Insufficiency+1 more
University College, London40 enrolled1 locationNCT07597798
Recruiting
Phase 1Phase 2

A Pilot Presurgical Trial of REGN5678 (Anti-PSMA x CD28) in Patients With High-risk, Localized Prostate Cancer Followed by Radical Prostatectomy

Prostate CancerRadical Prostatectomy
M.D. Anderson Cancer Center42 enrolled1 locationNCT06085664
Recruiting

Study of the Epidemiological, Clinical, Diagnostic, and Therapeutic Characteristics of Prostate Cancers in Algeria

Prostate CancerProstate Cancer MetastaticProstate Cancer (Adenocarcinoma)+3 more
Société Algérienne de Formation et Recherche en Oncologie2,000 enrolled24 locationsNCT07484971
Recruiting
Phase 3

64Cu-SAR-bisPSMA Positron Emission Tomography: A Phase 3 Study of Participants With Biochemical Recurrence of Prostate Cancer

Prostate CancerCryotherapyProstate Cancer Recurrent+3 more
Clarity Pharmaceuticals Ltd220 enrolled28 locationsNCT06970847
Recruiting
Not Applicable

The Effect of Mobile-Based Perioperative Education on Urinary Incontinence and Erectile Function After Radical Prostatectomy

Prostate Cancer (Post Prostatectomy)Erectile Dysfunction Following Radical ProstatectomyUrinary Incontinence (UI)
Giresun University78 enrolled1 locationNCT07520916
Recruiting

Prognostic Value of Early Postoperative Prostate-Specific Antigen for Oncological Outcomes After Radical Prostatectomy

Prostate Cancer (Adenocarcinoma)Radical ProstatectomyProstate Cancer (Post Prostatectomy)+2 more
Lithuanian University of Health Sciences500 enrolled1 locationNCT07516886
Recruiting

Effect Of Trendelenburg Position And Pneumoperitoneum On Optic Nerve Sheath Diameter In Robot-Assisted Prostatectomy

Robot-assisted Radical ProstatectomyProstate CancerOptic Nerve Sheath Diameter+1 more
Ege University50 enrolled1 locationNCT07491198
Recruiting
Not Applicable

Safety and Tolerability of a Novel Implantable Device for the Treatment of Erectile Dysfunction

Erectile Dysfunction Following Radical Prostatectomy
Comphya Australia20 enrolled4 locationsNCT05650866
Recruiting
Not Applicable

A Study Looking at a New Nerve Surgery to Help Men Regain Erections After Prostate Cancer Surgery

Prostate CancerErectile Dysfunction Following Radical Prostatectomy
Sir Mortimer B. Davis - Jewish General Hospital100 enrolled1 locationNCT07188064
Recruiting

Exploring Clinical Utility of Wearables for the Bladder in Pelvic Health Physical Therapy Clinics

Bladder DysfunctionPostpartum Bladder DysfunctionPost-prostatectomy Bladder Dysfunction
University of California, San Francisco25 enrolled1 locationNCT07451106
Recruiting
Not Applicable

Pre-Operative Nurse-Led Education With Direct Physiotherapy Referral to Reduce Post-Prostatectomy Incontinence

Prostate CancerUrinary IncontinencePostoperative Complications+1 more
Royal College of Surgeons, Ireland80 enrolled1 locationNCT07426861
Recruiting
Not Applicable

Effect of Education to be Provided to Patients to Undergo TURP With Mobile Application on Patient Outcomes

Prostate Cancer (Post Prostatectomy)
Tarsus University68 enrolled1 locationNCT06687538
Recruiting

Salvage Ultrahypofractionated Postoperative External Radiotherapy For Biochemical Recurrence

Prostate Cancer (Post Prostatectomy)
University of Milano Bicocca50 enrolled1 locationNCT06941363
Recruiting
Not Applicable

Efficacy of Low-intensity Shockwave vs Radial Wave for Treatment of Erectile Dysfunction and Pelvic Pain

Erectile DysfunctionErectile Dysfunction Following Radiation TherapyErectile Dysfunction Following Radical Prostatectomy+4 more
The Cleveland Clinic186 enrolled1 locationNCT05868668