Early Phase 1 Rectal Cancer Clinical Trials

10 recruitingEarly Phase 1

What is a Early Phase 1 trial?

Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.

Showing 110 of 10 trials

Recruiting
Early Phase 1

INFINITIVE: ImmuNotherapy For PatIeNts wIth colorecTal LIVer MEtastases

Colorectal Cancer Metastatic
Northwell Health10 enrolled1 locationNCT07172282
Recruiting
Early Phase 1

Pilot Study of an Implantable Microdevice for In Situ Evaluation of Drug Response in Patients With Colorectal Liver Metastasis

Colorectal Cancer Metastatic
Northwell Health10 enrolled2 locationsNCT07193862
Recruiting
Early Phase 1

Universal CAR-T Cells (REVO-UWD-01) for Metastatic Colorectal Cancer

Metastatic Colorectal CancerCRC (Colorectal Cancer)
Wondercel Biotech (ShenZhen)30 enrolled2 locationsNCT06653010
Recruiting
Early Phase 1

COLONYVAQ™, a Quantum-Classical Guided Personalized Neoantigen Vaccine for MSS Stage III Colorectal Cancer

Colorectal Cancer MetastaticColorectal Cancer Stage IIIColorectal Cancer Stage IV
Biogenea Pharmaceuticals Ltd.12 enrolled1 locationNCT07328087
Recruiting
Early Phase 1

An Investigational Scan (64Cu-Labeled M5A Antibody) in Combination With SOC Chemotherapy and Radiotherapy in Locally Advanced Rectal Cancer

Locally Advanced Rectal CarcinomaStage III Rectal Cancer AJCC v8Stage IIIA Rectal Cancer AJCC v8+2 more
City of Hope Medical Center15 enrolled1 locationNCT05245786
Recruiting
Early Phase 1

Active Surveillance and Chemotherapy Before Surgery in Treating Participants With Stage II-III Rectal Cancer

Rectal AdenocarcinomaStage II Rectal Cancer AJCC v8Stage III Rectal Cancer AJCC v8+6 more
M.D. Anderson Cancer Center120 enrolled1 locationNCT03594630
Recruiting
Early Phase 1

Neuroprotective Potential of Cannabidiol (CBD) in Preventing Oxaliplatin (Ox)-Induced Neuropathy

Metastatic Colorectal Cancer (CRC)Oxaliplatin Induced Peripheral Neuropathy in Cancer PatientsPeripheral Neuropathy Due to Chemotherapy
Fox Chase Cancer Center30 enrolled1 locationNCT07167446
Recruiting
Early Phase 1

A Dose-Expansion Trial of Intravenous HNF4α srRNA for Unresectable or Metastatic Colorectal Cancer

Colorectal Cancer MetastaticColorectal Cancer RecurrentColorectal Cancer Stage IV
Shanghai Changzheng Hospital20 enrolled1 locationNCT07050394
Recruiting
Early Phase 1

Autologous CAR-T Cells (WD-01) for Metastatic Colorectal Cancer

Metastatic Colorectal CancerCRC (Colorectal Cancer)
Wondercel Biotech (ShenZhen)30 enrolled2 locationsNCT06675513
Recruiting
Early Phase 1

Chemokine and Co-stimulatory Molecule-modified Mesenchymal Stem Cells for the Treatment of Advanced Colorectal Cancer

Advanced Colorectal Cancer
Shanghai East Hospital30 enrolled1 locationNCT06446050