Regurgitation Clinical Trials

3 recruiting

Frequently Asked Questions

Common questions about Regurgitation clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 157 trials

Recruiting

TriClip Japan Post-Approval Study

Tricuspid Regurgitation
Abbott Medical Devices250 enrolled1 locationNCT07509658
Recruiting
Not Applicable

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

Mitral Valve Regurgitation
Medtronic Cardiovascular1,056 enrolled85 locationsNCT03242642
Recruiting
Not Applicable

Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial

Tricuspid RegurgitationTricuspid Valve InsufficiencyTricuspid Valve Disease
Edwards Lifesciences870 enrolled79 locationsNCT04097145
Recruiting

Investigation of Gastric Emptying by Gastric Ultrasonography in Diabetic Patients Treated With GLP-1 Receptors

Diabete Type 2RegurgitationPulmonary Aspiration During Anaesthetic Induction
University Hospital, Geneva38 enrolled1 locationNCT07506356
Recruiting
Not Applicable

Safety and Feasibility Study of the MitraFix® Transcatheter Mitral Valve System

Mitral Regurgitation (MR)
Mitrassist Lifesciences Limited Co., Ltd.5 enrolled1 locationNCT07501234
Recruiting
Not Applicable

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With at Least Mild FMR

Heart FailureCardiovascular DiseasesHeart Diseases+3 more
Cardiac Dimensions, Inc.300 enrolled92 locationsNCT03142152
Recruiting
Not Applicable

Clinical Safety and Efficacy of the VDyne Transcatheter Tricuspid Valve Replacement System for the Treatment of Tricuspid Regurgitation ( VISTA-US)

Tricuspid RegurgitationTricuspid Valve DiseaseTricuspid Valvular Disorders
VDyne, Inc.30 enrolled11 locationsNCT05848284
Recruiting
Not Applicable

J-Valve Transfemoral Pivotal Study

Aortic Valve RegurgitationAortic Valve Disease Mixed
JC Medical, Inc., an affiliate of Edwards Lifesciences LLC194 enrolled37 locationsNCT06455787
Recruiting
Not Applicable

Valve Hemodynamic Optimization Based on Doppler-Echocardiography vs Catheterization Measurements Following ViV TAVR

Aortic Valve StenosisAortic Valve RegurgitationProsthesis Failure
Institut universitaire de cardiologie et de pneumologie de Québec, University Laval310 enrolled7 locationsNCT05459233
Recruiting

Berlin Registry of Right Heart Interventions

Tricuspid RegurgitationPulmonary Regurgitation
Charite University, Berlin, Germany200 enrolled1 locationNCT04570163
Recruiting
Not Applicable

Artificial Intelligence in Aortic Regurgitation

Aortic Regurgitation Disease
Chinese University of Hong Kong540 enrolled1 locationNCT07486271
Recruiting
Not Applicable

Efficacy and Safety of Catheter abLation in patiEnts With seVere mitrAl regurgiTation and pErsistent Atrial Fibrillation: a Randomized Controlled Trial

Atrial Fibrillation (AF)Catheter AblationAtrial Functional Mitral Regurgitation
Beijing Anzhen Hospital146 enrolled17 locationsNCT06883864
Recruiting

Abbott Cephea Mitral Valve Disease Registry

Mitral RegurgitationMitral StenosisMitral Valve Disease+4 more
Abbott Medical Devices1,000 enrolled19 locationsNCT07069673
Recruiting

Evaluation of the Impact of Interventional Treatments for Symptomatic, Severe Tricuspid Valve Insufficiency on Renal Integrity and Function, as Well as on Physical Function and Activity in Older Adults.

FrailtyTricuspid RegurgitationCardio-Renal Syndrome+1 more
Robert Bosch Medical Center100 enrolled1 locationNCT07464106
Recruiting

Prospective Evaluation of AI-ECG for SHD Detection

Heart Failure With Preserved Ejection Fraction (HFpEF; Diagnosis)Valvular Heart Disease Stenosis and Regurgitation (Diagnosis)Pulmonary Hypertension (Diagnosis)+1 more
Imperial College London590 enrolled5 locationsNCT07057466
Recruiting
Not Applicable

TTVR Early Feasibility Study

Tricuspid Regurgitation
Medtronic Cardiovascular150 enrolled20 locationsNCT04433065
Recruiting
Phase 4

STrategies for Antithrombotic tReatment Following Transcatheter Edge-to-Edge Repair in Patients Without an Indication for Oral Anticoagulant

Mitral Regurgitation
Chinese Academy of Medical Sciences, Fuwai Hospital1,032 enrolled1 locationNCT07007143
Recruiting
Phase 4

STrategies for Antithrombotic tReatment Following Transcatheter Edge-to-Edge Repair in Patients With an Indication for Oral Anticoagulant

Mitral Regurgitation
Chinese Academy of Medical Sciences, Fuwai Hospital880 enrolled1 locationNCT06901466
Recruiting
Phase 1

A Clinical Study Evaluating the Replacement of the Native Mitral Valve Using the ReValve System

Mitral Regurgitation
ReValve Solutions Inc.20 enrolled3 locationsNCT07450911
Recruiting
Not Applicable

Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds (PRIMARY)

Mitral Valve Regurgitation
Annetine Gelijns450 enrolled61 locationsNCT05051033