Heartburn Clinical Trials

7 recruitingLast updated: July 25, 2026

There are 7 actively recruiting heartburn clinical trials across 4 countries. Studies span Not Applicable, Phase 3. Top locations include Houston, Texas, United States, Jacksonville, Florida, United States, Moscow, Russia. Updated daily from ClinicalTrials.gov.


Heartburn Trials at a Glance

7 actively recruiting trials for heartburn are listed on ClinicalTrialsFinder across 6 cities in 4 countries. The largest study group is Not Applicable with 4 trials, with the heaviest enrollment activity in Houston, Jacksonville, and Moscow. Lead sponsors running heartburn studies include M.D. Anderson Cancer Center, Mayo Clinic, and Cellmedis.

Browse heartburn trials by phase

Treatments under study

About Heartburn Clinical Trials

Looking for clinical trials for Heartburn? There are currently 7 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Heartburn trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Heartburn clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 17 of 7 trials

Recruiting
Not Applicable

New Topical tReatment Options for Symptomatic patiEnts With Nonerosive gastroesophageaL Reflux dIsease (The RELIEF Trial)

GERD (Gastroesophageal Reflux Disease)NERDRegurgitation, Gastric+1 more
Cellmedis50 enrolled1 locationNCT07624383
Recruiting
Phase 3

Domperidone in Treating Patients With Gastrointestinal Disorders

Nausea and VomitingGastroparesisDyspepsia+4 more
M.D. Anderson Cancer Center200 enrolled1 locationNCT01696734
Recruiting
Not Applicable

A Clinical Trial of PepZinGI® for Acute Heartburn Relief and Sleep Outcomes

Heartburn
NutriScience Innovations, LLC50 enrolled1 locationNCT07379645
Recruiting
Not Applicable

A Study of Breath Testing for Small Intestinal Bacterial Overgrowth

Gastroesophageal RefluxRegurgitationHeartburn
Mayo Clinic50 enrolled1 locationNCT05976165
Recruiting

A Study of the Safety of Vonoprazan Exposure in Pregnant Women and Their Offspring

Helicobacter Pylori InfectionErosive EsophagitisSymptomatic Non-erosive Gastroesophageal Reflux Disease+1 more
Phathom Pharmaceuticals, Inc.728 enrolled1 locationNCT06660342
Recruiting
Not Applicable

Comparative Pharmacodynamics and Pharmacodynamics Equivalence of Antareit 800 mg/10 ml Oral Suspension and Riopan 800 mg Chewable Tablets in Healthy Volunteers

Acid-dependent Diseases of the Gastrointestinal TractSymptomatic Treatment of Gastric and Duodenal UlcersHeartburn
Valenta Pharm JSC50 enrolled2 locationsNCT06098742
Recruiting

Effect of KFibre in heartburn

Acid Reflux diseaseHeartburn
University of Tasmania40 enrolled1 locationACTRN12619001204134