Phase 3 REST Clinical Trials

20 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 120 of 20 trials

Recruiting
Phase 2Phase 3

A Self-Controlled Study on the Treatment of Restless Legs Syndrome in Uremia With Dipyridamole

Restless Leg Syndrome Due to Uraemia
Yunfeng Xia80 enrolled1 locationNCT07199504
Recruiting
Phase 2Phase 3

Resuscitation Enhancement to Avoid Rearrest Through Evidence-based Strategies in Prehospital Post-resuscitation Care

Out of Hospital Cardiac Arrest (OHCA)
Siriraj Hospital318 enrolled1 locationNCT07239908
Recruiting
Phase 3

Study of Placental Vascularization Using Contrast Ultrasound

Fetal Growth Restriction
Central Hospital, Nancy, France30 enrolled1 locationNCT06497959
Recruiting
Phase 2Phase 3

Early Double Sequential Defibrillation in Out of Hospital Cardiac Arrest

sudden deathVentricular FibrillationOut-of-hospital cardiac arrest+3 more
Gabriel Riva916 enrolled14 locationsNCT07174986
Recruiting
Phase 3

The Application of Positive End-Expiratory Pressure in Out-of-Hospital Cardiac Arrest: The Lazarus-PEEP Trial.

Out of Hospital Cardiac Arrest (OHCA)Cardiac Arrest (CA)Positive End-expiratory Pressure (PEEP)+1 more
University Hospital, Ghent132 enrolled7 locationsNCT06939335
Recruiting
Phase 3

Early Amiodarone in Shockable Cardiac Arrest

Cardiac Arrest
Oregon Health and Science University585 enrolled1 locationNCT06680869
Recruiting
Phase 3

Prophylactic Anti-aRrhythmic Therapy With Amiodarone in Critically Ill Patients Admitted for an Out-of-hospital Cardiac Arrest With Initial Shockable Rhythm

Ventricular Arrhythmias and Cardiac Arrest
Versailles Hospital674 enrolled29 locationsNCT06835491
Recruiting
Phase 3

Chronic Hypertension and Acetyl Salicylic Acid in Pregnancy

Pre-EclampsiaIntrauterine Growth RestrictionAspirin+3 more
Centre Hospitalier Intercommunal Creteil500 enrolled20 locationsNCT04356326
Recruiting
Phase 3

The Effect of phoSPHocreatine on mEdical Emergency Team (Met) tREated Patients

Respiratory FailureCardiac FailureCardiac Arrest+7 more
Università Vita-Salute San Raffaele400 enrolled1 locationNCT06503016
Recruiting
Phase 3

Effect and Safety of Flecainide and Metoprolol Versus Metoprolol Alone to Suppress Ventricular Arrhythmias in Arrhythmic Mitral Valve Prolapse

Mitral valve prolapseVentricular Arrhythmias and Cardiac Arrest
Oslo University Hospital50 enrolled1 locationNCT05631730
Recruiting
Phase 2Phase 3

POHCA Resuscitation: Evaluation of IM Epinephrine

Pediatric Out-of-Hospital Cardiac Arrest
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's284 enrolled1 locationNCT05166343
Recruiting
Phase 2Phase 3

Gut Microbiome Profiles in Patients with Chemotherapy-induced Neuropathy in the RCT OzoParQT (NCT06706544).

Chemotherapy-induced Peripheral Neuropathy (CIPN)NumbnessParesthesia+1 more
Bernardino Clavo, MD, PhD42 enrolled1 locationNCT06799351
Recruiting
Phase 2Phase 3

Ozone Treatment in Paresthesia (Numbness, Tingling) Secondary to Chemotherapy-induced Peripheral Neuropathy

Chemotherapy-induced Peripheral Neuropathy (CIPN)NumbnessParesthesia+1 more
Bernardino Clavo, MD, PhD42 enrolled1 locationNCT06706544
Recruiting
Phase 3

The Danish Out-of-Hospital Cardiac Arrest Study

Out-of-hospital cardiac arrestPost Cardiac Arrest Syndrome
Christian Hassager1,000 enrolled5 locationsNCT05895838
Recruiting
Phase 2Phase 3

Surviving PEA in Roanoke (SPEAR) Study

Cardiac ArrestPulseless Electrical Activity
Carol Bernier342 enrolled1 locationNCT05283850
Recruiting
Phase 3

VAsopressin and STeroids in Addition to Adrenaline in Cardiac Arrest - a Randomized Clinical Trial

Cardiac Arrest;In-hospital Cardiac Arrest; Methylprednisolone; Vasopressin; Adrenaline; Randomized Clinical Trial
Tiohundra AB1,276 enrolled2 locationsNCT05139849
Active
Phase 3

A randomised controlled trial of antenatal melatonin supplementation in fetal growth restriction for fetal neuroprotection.

Fetal NeuroprotectionFetal Growth Restriction (FGR)
Monash Health336 enrolled14 locationsACTRN12617001515381
Completed
Phase 2Phase 3

STRIDER (NZAus): A randomised placebo-controlled trial of a new therapy (sildenafil) to help growth in severely growth restricted fetuses at very early gestations.

Severe early onset fetal growth restriction
University of Auckland122 enrolled1 locationACTRN12612000584831
Recruiting
Phase 3

Is 3 minutes of CPR before defibrillation, better than immediate defibrillation, for patients who are found to be in cardiac arrests by paramedics?

Cardiac arrest, ventricular fibrillation
South Australia Ambulance Service300 enrolledACTRN12607000401459
Not Yet Recruiting
Phase 3

Paramedic cooling compared with hospital cooling after resuscitation from cardiac arrest

Out-of-hospital cardiac arrest
Metropolitan Ambulance Service600 enrolled1 locationACTRN12605000179639