Phase 2 Rheumatoid Arthritis Clinical Trials
45 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 45 trials
Recruiting
Phase 2
A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis
Rheumatoid Arthritis
AbbVie180 enrolled98 locationsNCT06972446
Recruiting
Phase 1Phase 2
A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2)
Rheumatoid ArthritisIdiopathic Inflammatory MyopathiesSystemic Sclerosis+1 more
Nkarta, Inc.240 enrolled17 locationsNCT06733935
Recruiting
Phase 2
Desloratadine as Adjunct Therapy for Rheumatoid Arthritis
Rheumatoid ArthritisRheumatoid Arthritis (RA)
Horus University60 enrolled1 locationNCT07632872
Recruiting
Phase 2
Effect of Roflumilast as Add-On Therapy in Rheumatoid Arthritis
Rheumatoid ArthritisRheumatoid Arthritis (RA)
Horus University50 enrolled1 locationNCT07632846
Recruiting
Phase 2
A Study to Assess the Efficacy and Safety of RO7790121 in Participants With Moderate to Severe Rheumatoid Arthritis Who Have Not Responded to or Who Cannot Tolerate Tumor Necrosis Factor (TNF) and/or Janus Kinase (JAK Inhibitors)
Rheumatoid Arthritis
Hoffmann-La Roche160 enrolled51 locationsNCT07137598
Recruiting
Phase 1Phase 2
A Study to Assess Safety, Cellular Kinetics and Exploratory Efficacy of Rapcabtagene Autoleucel in Rheumatoid Arthritis and Sjogren's Disease
Rheumatoid Arthritis (RA) and Sjögren's Disease (SjD)
Novartis Pharmaceuticals27 enrolled12 locationsNCT07048197
Recruiting
Phase 2
Phase IIb Clinical Study to Assess the Efficacy and Safety of GenSci120 Injection in Patients With Moderately to Severely Active RA Who Have an Inadequate Response to at Least One DMARD
Rheumatoid Arthritis
Changchun GeneScience Pharmaceutical Co., Ltd.450 enrolled1 locationNCT07423533
Recruiting
Phase 2
AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.
SclerodermaRheumatoid Arthritis (RA)Sjogren Syndrome+6 more
Artiva Biotherapeutics, Inc.90 enrolled52 locationsNCT06991114
Recruiting
Phase 2
A Study With CIT-013 in RA Patients
Rheumatoid Arthritis
Citryll BV88 enrolled24 locationsNCT06567470
Recruiting
Phase 1Phase 2
Controlling Hyperactive Immunity With Long-lived Lymphocytes
Rheumatoid Arthritis (RA)Autoimmune Rheumatologic DiseaseDiffuse Cutaneous Systemic Sclerosis+1 more
Quell Therapeutics Limited16 enrolled6 locationsNCT07473154
Recruiting
Phase 2
Effect of Roflumilast and Desloratadine as Add-On Therapy in Patients With Rheumatoid Arthritis
Rheumatoid Arthritis
Horus University90 enrolled1 locationNCT07566351
Recruiting
Phase 2
A Phase 2 Master Protocol Assessing Inebilizumab and Blinatumomab in Autoimmune Diseases
Systemic Lupus ErythematosusActive Refractory Rheumatoid Arthritis
Amgen220 enrolled54 locationsNCT06570798
Recruiting
Phase 2
A Study of SPY072 in Rheumatic Disease
Rheumatoid ArthritisPsoriatic ArthritisRheumatic Diseases+5 more
Spyre Therapeutics, Inc.285 enrolled64 locationsNCT07148414
Recruiting
Phase 2
A Study to Investigate Efficacy and Safety of AZD1163 in Participants With Rheumatoid Arthritis
Rheumatoid Arthritis
AstraZeneca320 enrolled144 locationsNCT07276581
Recruiting
Phase 2
A Study to Assess the Safety and Efficacy of Different Doses of ELV001 to Treat Active Rheumatoid Arthritis in Patients With an Inadequate Response to Methotrexate and Tumor Necrosis Factor Inhibition (START SYNERGY)
Active Rheumatoid Arthritis
Elevara Medicines Limited180 enrolled29 locationsNCT07409103
Recruiting
Phase 2
A Study Evaluating the Safety and Efficacy of Inhaled AP01 in Participants With Progressive Pulmonary Fibrosis
Progressive Pulmonary FibrosisInterstitial Lung DiseasePulmonary Fibrosis+7 more
Avalyn Pharma Inc.375 enrolled152 locationsNCT06329401
Recruiting
Phase 2
A Study Investigating the Efficacy and Safety of BGB-45035 Versus Placebo in Adults With Moderate to Severe Active Rheumatoid Arthritis
Rheumatoid Arthritis
BeiGene90 enrolled29 locationsNCT07100938
Recruiting
Phase 2
COVID-19 Booster and IIV Schedule in Immunocompromised Hosts
COVID-19Inflammatory Bowel DiseaseRheumatoid Arthritis (RA)+5 more
McGill University Health Centre/Research Institute of the McGill University Health Centre660 enrolled3 locationsNCT06599658
Recruiting
Phase 2
A Phase II Trial of SHR-3045 Injection in Patients With Rheumatoid Arthritis
Moderate to Severe Active Rheumatoid Arthritis
Guangdong Hengrui Pharmaceutical Co., Ltd30 enrolled1 locationNCT07233655
Recruiting
Phase 2
Safety and Efficacy of TollB-001 Tablets in Moderate to Severe Rheumatoid Arthritis
Rheumatoid Arthritis (RA)
Toll Biotech Co. Ltd. (Beijing)24 enrolled6 locationsNCT07408024