Phase 3 RNA Clinical Trials
22 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 22 trials
Recruiting
Phase 3
PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation
InfectionsInjury LegAmputation+6 more
Major Extremity Trauma Research Consortium250 enrolled13 locationsNCT05699174
Recruiting
Phase 3
Suzetrigine in Total Hip Arthroplasty
Total Hip Replacement SurgeryPainPain Management+13 more
Hospital for Special Surgery, New York210 enrolled1 locationNCT07226700
Recruiting
Phase 3
A Study to Evaluate How Pozelimab + Cemdisiran Combination Therapy Works in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) Whose Current Treatment is Not Working Efficiently
Paroxysmal nocturnal hemoglobinuria
Regeneron Pharmaceuticals35 enrolled13 locationsNCT07154745
Recruiting
Phase 3
Feasibility Study of Phase-contrast MRI for Flow in the External Carotid Branches Arteries
Carotid Artery, External
Centre Hospitalier Universitaire, Amiens80 enrolled1 locationNCT02829190
Recruiting
Phase 3
3% Diquafosol Ophthalmic Solution for Active Moderate-to-Severe Vernal Keratoconjunctivitis
Vernal Keratoconjunctivitis
The University of Hong Kong94 enrolled1 locationNCT06903884
Recruiting
Phase 3
Study to Assess the Pharmacokinetics, Safety, and Tolerability of Iptacopan in Pediatric PNH Patients
Paroxysmal Nocturnal Hemoglobinuria, PNH
Novartis Pharmaceuticals12 enrolled13 locationsNCT06934967
Recruiting
Phase 2Phase 3
PRECISION-BP: Precision Chronopharamacotherapy Targeting NP-RAAS-BP Rhythm Axis
ObesityCardiovascular DiseasesHypertension+3 more
University of Alabama at Birmingham160 enrolled1 locationNCT04971720
Recruiting
Phase 3
A Study in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) to Evaluate How Safe Long-term Treatment With Pozelimab + Cemdisiran Combination Therapy is and How Well it Works
Paroxysmal nocturnal hemoglobinuria
Regeneron Pharmaceuticals202 enrolled43 locationsNCT05744921
Recruiting
Phase 3
A Trial of Chinese Traditional Medicine Combining With Intradermal Acupuncture for Treating Precocious Puberty
TreatmentPrecocious PubertyAcupuncture+1 more
Children's Hospital of Fudan University170 enrolled2 locationsNCT06510764
Recruiting
Phase 3
Safest Choice of Antihypertensive Regimen for Postpartum Hypertension
Postpartum ComplicationHigh Blood PressureMaternal Hypertension
Loma Linda University500 enrolled1 locationNCT05551104
Recruiting
Phase 3
KHENERFIN Study: A Trial to Evaluate the Efficacy and Safety of Sonlicromanol in Primary Mitochondrial Diseases
Mitochondrial DiseasesMaternally Inherited Diabetes and Deafness (MIDD)Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-like Episodes (MELAS)+1 more
Khondrion BV220 enrolled10 locationsNCT06451757
Recruiting
Phase 3
Study of Danicopan as Add-on Treatment to Ravulizumab or Eculizumab in Pediatric Participants With PNH Who Have Clinically Significant Extravascular Hemolysis
PNHExtravascular HemolysisParoxysmal nocturnal hemoglobinuria
Alexion Pharmaceuticals, Inc.6 enrolled4 locationsNCT06449001
Recruiting
Phase 3
Omegapres Versus Solifenacin and Mirabegron Combination Therapy in Treatment of Primary MNE
Nocturnal enuresis in children
Mansoura University120 enrolled1 locationNCT07199894
Recruiting
Phase 3
Study of Safety and Efficacy of MY008211A in Patients With Residual Anemia Despite Anti-C5 Antibody Treatment
Paroxysmal nocturnal hemoglobinuria
Wuhan Createrna Science and Technology Co., Ltd20 enrolled1 locationNCT06932471
Recruiting
Phase 3
Study of Safety and Efficacy of MY008211A in Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients Who Are Naive to Complement Inhibitor Therapy
Paroxysmal nocturnal haemoglobinuria (PNH)
Wuhan Createrna Science and Technology Co., Ltd66 enrolled2 locationsNCT06932744
Recruiting
Phase 2Phase 3
Long-term Safety and Tolerability of MY008211A Tablets in Patients With Paroxysmal Nocturnal Hemoglobinuria
Paroxysmal Nocturnal Hemoglobinuria, PNH
Wuhan Createrna Science and Technology Co., Ltd120 enrolled1 locationNCT06933914
Recruiting
Phase 3Phase 4
Azithromycin at birth: Single dose azithromycin shortly before birth - what is the impact on infection rates in high-risk mothers and babies? A randomised controlled trial
infant infectionsmaternal post-natal infections
Menzies School of Health Research1,548 enrolled1 locationACTRN12624000247572
Recruiting
Phase 3
Convalescent Plasma Collection and Treatment in Pediatrics and Adults
COVID19CoronavirusCoronavirus Infection+2 more
West Virginia University240 enrolled1 locationNCT04376034
Completed
Phase 3
Randomized controlled trial of the Effect of intraVenous iron on Anaemia in Malawian Pregnant women
Infant anaemiaMaternal mortalityFatigue+5 more
University of Malawi, College of Medicine862 enrolled1 locationACTRN12618001268235
Recruiting
Phase 3
Patient-controlled analgesia with methoxyflurane (Penthrox inhaler) versus conventional endoscopist-provided sedation for colonoscopy: a randomized multi-centre trial
Alternative Pain relief in patients undergoing colonoscopy
Dr. Nam Q Nguyen300 enrolled3 locationsACTRN12613000709741