rotator cuff injuries Clinical Trials

17 recruitingLast updated: May 11, 2026

There are 17 actively recruiting rotator cuff injuries clinical trials across 13 countries. Studies span Not Applicable, Phase 1, Phase 2. Top locations include Baltimore, Maryland, United States, Ankara, Turkey (Türkiye), Ashland, Wisconsin, United States. Updated daily from ClinicalTrials.gov.


rotator cuff injuries Trials at a Glance

17 actively recruiting trials for rotator cuff injuries are listed on ClinicalTrialsFinder across 6 cities in 13 countries. The largest study group is Not Applicable with 10 trials, with the heaviest enrollment activity in Baltimore, Ankara, and Ashland. Lead sponsors running rotator cuff injuries studies include Hacettepe University, Smith & Nephew, Inc., and Duke University.

Browse rotator cuff injuries trials by phase

Treatments under study

About rotator cuff injuries Clinical Trials

Looking for clinical trials for rotator cuff injuries? There are currently 18 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new rotator cuff injuries trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about rotator cuff injuries clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 117 of 17 trials

Recruiting
Phase 1Phase 2

CBD for Pain Following Orthopedic Shoulder Surgery

Shoulder Osteoarthritisrotator cuff injuries
The Methodist Hospital Research Institute80 enrolled1 locationNCT06381791
Recruiting

Clinical Outcomes of Arthroscopic Surgeries for Shoulder and Knee Sports Injuries

Anterior Cruciate Ligament InjuriesShoulder Dislocation or SubluxationPosterior Cruciate Ligament Tear+3 more
Second Affiliated Hospital, School of Medicine, Zhejiang University500 enrolled1 locationNCT07501013
Recruiting

The Role of Pectoralis Minor Tightness in the Development of Rotator Cuff Tears

Shoulder impingement syndromePectoralis Minor TightnessPectoralis Minor Muscle Tension+1 more
Gazi University90 enrolled1 locationNCT07228936
Recruiting
Not Applicable

Therapeutic Exercise for Rotator Cuff Tendinopathy / Subacromial Pain Syndrome - Outcomes and Mechanisms

Rotator cuff tendinitisSubacromial Pain SyndromeRotator Cuff Tendinosis+1 more
University of Southern California60 enrolled1 locationNCT04923477
Recruiting
Not Applicable

Utility of Intermittent Cryo-Compression Versus Traditional Icing Following Arthroscopic Rotator Cuff Repair

Cryotherapy Effectrotator cuff injuries
Allina Health System100 enrolled1 locationNCT05095909
Recruiting
Not Applicable

Use of the REGENETEN™ Bioinductive Implant System in High Grade Partial-thickness Tears

rotator cuff injuries
Smith & Nephew, Inc.234 enrolled20 locationsNCT05444465
Recruiting
Not Applicable

Safety and Efficacy of Platelet-Rich Plasma Combined With Compound Betamethasone in Arthroscopic Surgery for Rotator Cuff Injury With Shoulder Adhesion: A Prospective, Multicenter, Randomized Controlled Trial

Adhesionsrotator cuff injuries
Second Affiliated Hospital of Nanchang University70 enrolled1 locationNCT07348016
Recruiting
Not Applicable

Effectiveness of Telerehabilitation as an Alternative to Outpatient Physiotherapy in the 1 Month After Arthroscopic Rotator Cuff Repair Surgery

rotator cuff injuries
Istituto Ortopedico Rizzoli46 enrolled2 locationsNCT06744218
Recruiting
Not Applicable

Investigation of the Effects of Kettlebell Training

Shoulder Painrotator cuff injuries
Hacettepe University38 enrolled2 locationsNCT07289893
Recruiting

Evaluating Hemidiaphragmatic Paralysis With Prolonged Neural Blockade From an Interscalene Brachial Plexus Block

Rotator Cuff RepairShoulder PainRotator Cuff Tears+7 more
Duke University60 enrolled1 locationNCT04209504
Recruiting
Not Applicable

Postoperative Rotator Cuff Rehabilitation: Functional, Pain and Sleep Quality

PainSleepRehabilitation+3 more
LAURA CASTILLO VEJAR50 enrolled2 locationsNCT07135375
Recruiting
Not Applicable

Subscap Reverse Shoulder Arthroplasty

Shoulder Injuriesrotator cuff injuries
University of Maryland, Baltimore118 enrolled1 locationNCT05344898
Recruiting
Not Applicable

The Effect of a Custom Pillow on Sleep Quality in Patients With Nonoperative Rotator Cuff Syndrome

rotator cuff injuries
Rhode Island Hospital80 enrolled1 locationNCT05011331
Recruiting
Not Applicable

Slow and Accelerated Rehabilitation Protocols

Rotator Cuff TearsPain, Shoulderrotator cuff injuries
Hacettepe University38 enrolled1 locationNCT05450510
Recruiting

Evaluation Of Outcomes Following Rotator Cuff Repair Using the REGENETEN Bioinductive Implant: A Prospective, Multi-Center Global Registry

rotator cuff injuries
Smith & Nephew, Inc.400 enrolled19 locationsNCT06857084
Recruiting

From Rotator Cuff Repair to Reverse Shoulder Arthroplasty - Clinical and Radiological Results

Rotator Cuff Tear ArthropathyRotator Cuff Tearsrotator cuff injuries
Lovisenberg Diakonale Hospital733 enrolled1 locationNCT06644729
Recruiting

The Western Ontario Rotator Cuff Index Arabic Version

Surveys and Questionnairesrotator cuff injuries
Cairo University400 enrolled1 locationNCT05300607